TROP2- and CDH6-Directed ADCs in Gynecologic Cancers — An Interview with Dr Ramez Eskander on Key Presentations from the Society of Gynecologic Oncology 2026 Annual Meeting

TROP2- and CDH6-Directed ADCs in Gynecologic Cancers — An Interview with Dr Ramez Eskander on Key Presentations from the Society of Gynecologic Oncology 2026 Annual Meeting

Featuring an interview with Dr Ramez Eskander, including the following topics:

  • Overview of antibody-drug conjugates (ADCs) and their role in the management of gynecologic cancers; considerations in sequencing (0:00)
  • Choosing between FRɑ- and HER2-directed ADCs for dually eligible patients; role of antigenic target in predicting efficacy benefit of ADCs (7:53)
  • Comparative efficacy and safety of ADCs and conventional chemotherapy (12:58)
  • Current and investigational targets of ADCs in gynecologic cancers (17:14)
  • Current research surrounding raludotatug deruxtecan (R-DXd) and its potential role in clinical practice (21:56)
  • Safety and tolerability profiles of ADCs, including R-DXd, and potential mitigation strategies (27:36)
  • Overview of available TROP2-directed ADCs for gynecologic cancers, including key clinical data (33:34)
  • Evolving use of TROP2-directed ADCs for gynecologic cancers in clinical trials (39:05)
  • Oral mucositis/stomatitis associated with TROP2-directed ADCs and potential mitigation strategies (44:38)

CME information and select publications

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Episoder(48)

For Oncology Nurses: Ovarian Cancer — Proceedings from the 2026 Annual ONS Congress

For Oncology Nurses: Ovarian Cancer — Proceedings from the 2026 Annual ONS Congress

Featuring perspectives from Dr Bradley J Monk, Dr David M O’Malley, Ms Kathryn M Schlenker and Ms Jaclyn Shaver, moderated by Dr O’Malley, including the following topics: Introduction (00:00)Overview ...

23 Jul 1h 30min

Endometrial Cancer — Proceedings from a Session Held in Conjunction with the 2026 ASCO Annual Meeting

Endometrial Cancer — Proceedings from a Session Held in Conjunction with the 2026 ASCO Annual Meeting

Featuring perspectives from Dr Floor J Backes, Dr Brian M Slomovitz and Dr Shannon N Westin, moderated by Dr Westin, including the following topics:Introduction (00:00)Current Up-Front Chemoimmunother...

20 Jul 1h 29min

Ovarian Cancer — Proceedings from a Session Held in Conjunction with the 2026 ASCO Annual Meeting

Ovarian Cancer — Proceedings from a Session Held in Conjunction with the 2026 ASCO Annual Meeting

Featuring perspectives from Dr Ramez N Eskander, Dr Ursula Matulonis, Dr Kathleen N Moore, Dr Alexander B Olawaiye and Dr David M O'Malley, moderated by Dr Moore, including the following topics:Introd...

15 Jul 2h 1min

Endometrial Cancer — Microlearning Activity 2: Proceedings from an Independent Satellite Symposium during the SGO Annual Meeting on Women’s Cancer

Endometrial Cancer — Microlearning Activity 2: Proceedings from an Independent Satellite Symposium during the SGO Annual Meeting on Women’s Cancer

Featuring perspectives from Dr Floor J Backes, Dr Matthew A Powell and Dr Ritu Salani, moderated by Dr Salani, including the following topics:Case: A woman in her late 60s presents with mismatch repai...

12 Jul 15min

Endometrial Cancer — Microlearning Activity 1: Proceedings from an Independent Satellite Symposium during the SGO Annual Meeting on Women’s Cancer

Endometrial Cancer — Microlearning Activity 1: Proceedings from an Independent Satellite Symposium during the SGO Annual Meeting on Women’s Cancer

Featuring perspectives from Dr Floor J Backes, Dr Matthew A Powell and Dr Ritu Salani, moderated by Dr Salani, including the following topics:Case: A woman in her late 70s with de novo metastatic mism...

10 Jul 11min

Endometrial Cancer — An Interview with Dr Floor J Backes

Endometrial Cancer — An Interview with Dr Floor J Backes

Featuring an interview with Dr Floor J Backes, including the following topics:Overview of the treatment landscape of endometrial cancer (00:00)Immunotherapy for advanced endometrial cancer (03:58)Cont...

7 Jul 56min

For Oncology Nurses: Strategies to Safely and Effectively Implement Antibody-Drug Conjugates — Proceedings from the 2026 Annual ONS Congress

For Oncology Nurses: Strategies to Safely and Effectively Implement Antibody-Drug Conjugates — Proceedings from the 2026 Annual ONS Congress

Featuring perspectives from Ms Courtney Arn, Ms Jamie Carroll, Dr Edward B Garon, Dr Heather McArthur and Dr Kathleen N Moore, moderated by Dr Moore, including the following topics:Introduction (0:00)...

6 Jul 1h 28min

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