Targeting the PI3K/AKT/mTOR Pathway in HR-Positive Metastatic Breast Cancer — Proceedings from the 2026 Annual ONS Congress

Targeting the PI3K/AKT/mTOR Pathway in HR-Positive Metastatic Breast Cancer — Proceedings from the 2026 Annual ONS Congress

Featuring perspectives from Dr Reva Basho, Ms Kelly Fischer, Ms Melissa Rikal and Dr Seth Wander, moderated by Dr Wander, including the following topics:

  • Introduction (00:00)
  • Identification of Appropriate Candidates for Agents Targeting the PI3K/AKT/mTOR Pathway (3:45)
  • Role of Inavolisib in HR-Positive Metastatic Breast Cancer (mBC) (13:00)
  • Strategies to Prevent and Manage Hyperglycemia (27:02)
  • Clinical Utility of Capivasertib for HR-Positive mBC (38:09)
  • Mitigation and Management of Gastrointestinal Adverse Events (51:05)
  • Management of Dermatologic Adverse Events (59:58)
  • Potential Role of Gedatolisib in the Management of HR-Positive mBC (1:08:42)
  • Monitoring and Management of Cytopenias (1:21:23)

CME information and select publications

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Episoder(36)

Non-Small Cell Lung Cancer with a ROS1 Fusion — An Interview with Dr Alexander E Drilon

Non-Small Cell Lung Cancer with a ROS1 Fusion — An Interview with Dr Alexander E Drilon

Featuring an interview with Dr Alexander E Drilon, including the following topics:Overview of targetable biomarkers in lung cancer (0:00)Biomarker testing for genomic alterations in lung cancer (5:24)...

30 Sep 58min

Prostate Cancer — Proceedings from the 2026 Annual ONS Congress

Prostate Cancer — Proceedings from the 2026 Annual ONS Congress

Featuring perspectives from Mr Michael Lai, Dr Scott T Tagawa, Ms Stacy E Walker and Dr Evan Y Yu, moderated by Dr Tagawa, including the following topics:Introduction (0:00)Overview of Prostate Cancer...

31 Aug 1h 28min

Pancreatic Cancer — Proceedings from the 2026 Annual ONS Congress

Pancreatic Cancer — Proceedings from the 2026 Annual ONS Congress

Featuring perspectives from Ms Caroline Kuhlman, Dr Eileen M O'Reilly, Dr Philip A Philip and Ms Amanda K Wagner, moderated by Dr O'Reilly, including the following topics:Introduction (0:00)Clinical P...

24 Aug 1h 28min

Oral Selective Estrogen Receptor Degraders in Breast Cancer — Proceedings from the 2026 Annual ONS Congress

Oral Selective Estrogen Receptor Degraders in Breast Cancer — Proceedings from the 2026 Annual ONS Congress

Featuring perspectives from Ms Blanca Ledezma, Dr Marissa Marti-Smith, Dr Heather McArthur and Dr Ruth M O'Regan, moderated by Dr McArthur, including the following topics:Introduction (0:00)Current Cl...

18 Aug 1h 24min

Relapsed/Refractory Multiple Myeloma — Proceedings from the 2026 Annual ONS Congress

Relapsed/Refractory Multiple Myeloma — Proceedings from the 2026 Annual ONS Congress

Featuring perspectives from Dr Beth Faiman, Dr Natalie S Callander, Dr Hans Lee and Dr Mary Steinbach, moderated by Dr Callander, including the following topics:Introduction (00:00)Role of Chimeric An...

3 Aug 1h 26min

CDK4/6 Inhibitors for Breast Cancer — Proceedings from the 2026 Annual ONS Congress

CDK4/6 Inhibitors for Breast Cancer — Proceedings from the 2026 Annual ONS Congress

Featuring perspectives from Ms Kelly Fischer, Dr Marissa Marti-Smith, Dr Rita Nanda and Dr Ruth M O'Regan, moderated by Dr Nanda, including the following topics:Introduction (00:00)Advent of CDK4/6 In...

29 Jul 1h 29min

Ovarian Cancer — Proceedings from the 2026 Annual ONS Congress

Ovarian Cancer — Proceedings from the 2026 Annual ONS Congress

Featuring perspectives from Dr Bradley J Monk, Dr David M O’Malley, Ms Kathryn M Schlenker and Ms Jaclyn Shaver, moderated by Dr O’Malley, including the following topics: Introduction (00:00)Overview ...

23 Jul 1h 30min

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