Lead: Efficacy and safety of pharmacological interventions for the treatment of cocaine use disorder: A systematic review and network meta-analysis Addiction

Lead: Efficacy and safety of pharmacological interventions for the treatment of cocaine use disorder: A systematic review and network meta-analysis Addiction

Efficacy and safety of pharmacological interventions for the treatment of cocaine use disorder: A systematic review and network meta-analysis

Addiction

Cocaine use disorder (CUD) is an increasingly widespread concern worldwide. Various pharmacological treatments have been investigated for CUD, but their efficacy remains unclear, and none have been licensed for treatment. This systematic review and network meta-analysis assessed the comparative effectiveness, safety, and acceptability of pharmacological interventions for the treatment of CUD and prevention of relapse. The authors found no convincing evidence for the effectiveness of any pharmacological treatments for cocaine use disorder.

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Episoder(100)

Lead: 2025 National Survey on Drug Use and Health (NSDUH)

Lead: 2025 National Survey on Drug Use and Health (NSDUH)

2025 National Survey on Drug Use and Health (NSDUH) SAMHSA The 2025 National Survey on Drug Use and Health (NSDUH) shows encouraging trends among adolescents and young adults with broad declines acros...

4 Aug 7min

Lead: Association between GLP-1 receptor agonists and alcohol-related hospitalisations among adults with alcohol use disorder: Multi-target trial emulation study

Lead: Association between GLP-1 receptor agonists and alcohol-related hospitalisations among adults with alcohol use disorder: Multi-target trial emulation study

Association between GLP-1 receptor agonists and alcohol-related hospitalisations among adults with alcohol use disorder: Multi-target trial emulation study BMJ Open This retrospective cohort study usi...

28 Jul 6min

Lead: Trends in alcohol-related deaths in the United States over 55 years: 1968-2023

Lead: Trends in alcohol-related deaths in the United States over 55 years: 1968-2023

Trends in alcohol-related deaths in the United States over 55 years: 1968-2023 Alcohol, Clinical and Experimental Research  This study of alcohol-related mortality trends since 1968 used primarily dea...

21 Jul 6min

Lead: Comparison of buprenorphine treatment by virtual-only vs. traditional clinicians

Lead: Comparison of buprenorphine treatment by virtual-only vs. traditional clinicians

Comparison of buprenorphine treatment by virtual-only vs. traditional clinicians  Journal of Substance Use and Addiction Treatment  Few patients with opioid use disorder (OUD) receive medications for ...

14 Jul 7min

Lead: Adjunctive psychosocial interventions and opioid abstinence among patients receiving buprenorphine: A randomized clinical trial

Lead: Adjunctive psychosocial interventions and opioid abstinence among patients receiving buprenorphine: A randomized clinical trial

Adjunctive psychosocial interventions and opioid abstinence among patients receiving buprenorphine: A randomized clinical trial JAMA Network Open This randomized clinical trial of 340 adults with opio...

7 Jul 7min

Lead: Alcohol intake and health study: No protective effect at low levels, with mortality increasing to 1 in 25 at 14 Drinks per week

Lead: Alcohol intake and health study: No protective effect at low levels, with mortality increasing to 1 in 25 at 14 Drinks per week

Alcohol intake and health study: No protective effect at low levels, with mortality increasing to 1 in 25 at 14 Drinks per week Journal of Studies on Alcohol and Drugs This study used a cause-specific...

30 Jun 6min

Lead: Social media use trajectories and substance use experimentation: A prospective cohort study

Lead: Social media use trajectories and substance use experimentation: A prospective cohort study

Social media use trajectories and substance use experimentation: A prospective cohort study The American Journal of Psychiatry An analysis of data from more than 7,000 adolescents over 5 years found s...

23 Jun 8min

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