GLP-1 Medications and the Brain | Mood, Anxiety, Motivation & Dopamine Explained

GLP-1 Medications and the Brain | Mood, Anxiety, Motivation & Dopamine Explained

GLP-1 medications may affect far more than appetite and weight loss.

In this episode, we explore the growing evidence surrounding semaglutide, tirzepatide, and retatrutide and their potential effects on mood, anxiety, dopamine signaling, motivation, and compulsive behavior.

We discuss both the research and the real-world patient reports clinicians are increasingly hearing in practice.

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Episoder(46)

What Is Pinealon? Brain Aging, Neuroprotection, and the Evidence

What Is Pinealon? Brain Aging, Neuroprotection, and the Evidence

Check out The Peptide App here: thepeptide.app/explained What is Pinealon, and does this three-amino-acid peptide really protect the aging brain? Pinealon—also called EDR or Glu-Asp-Arg—is a synthetic...

31 Aug 22min

Khavinson Peptide Bioregulators: What Do They Actually Do?

Khavinson Peptide Bioregulators: What Do They Actually Do?

What are Khavinson peptide bioregulators, and what do they actually do? John Garrett examines the Russian research tradition behind organ-derived peptide complexes and synthetic ultrashort peptides. T...

30 Aug 19min

Did Your GLP-1 Stop Working? Appetite, Receptors and Weight-Loss Plateaus

Did Your GLP-1 Stop Working? Appetite, Receptors and Weight-Loss Plateaus

Does a weight-loss plateau mean your GLP-1 receptors have become desensitized? John separates cellular receptor biology from whole-body weight regulation and compares semaglutide, tirzepatide, and inv...

30 Aug 21min

Should You Be Using Peptides? The Honest Answer

Should You Be Using Peptides? The Honest Answer

Visit Peptide-Solutions.info for more info Check out App.PeptidesExplained.info Should you be using peptides? The honest answer is that not everyone should. Peptides are not a nutritional requirement,...

20 Aug 18min

ARA-290: Can It Repair Small Nerve Fibers?

ARA-290: Can It Repair Small Nerve Fibers?

ARA-290, also called cibinetide, is an investigational 11-amino-acid peptide designed from erythropoietin biology to activate tissue-protective signaling without stimulating red-blood-cell production....

18 Aug 17min

Lipo-C Injections: What Do They Actually Do?

Lipo-C Injections: What Do They Actually Do?

Check out Peptide.Solutions.info/Pathways and submit a request to see what companies I have partnered with to get products. Lipo-C injections are often marketed for fat burning, energy, liver support,...

12 Aug 15min

FOXO4-DRI: Can It Really Remove Senescent Cells and Reverse Aging?

FOXO4-DRI: Can It Really Remove Senescent Cells and Reverse Aging?

FOXO4-DRI has been called a "zombie-cell killer," a senolytic peptide, and even a possible anti-aging breakthrough. The mechanism is fascinating—but the claims have moved much faster than the human ev...

10 Aug 23min

ATX-304: AMPK Activation, Metabolic Demand, and the Limits of "Exercise in a Pill"

ATX-304: AMPK Activation, Metabolic Demand, and the Limits of "Exercise in a Pill"

ATX-304 is often called "exercise in a pill," but it is more accurate to describe it as an investigational oral small molecule that activates AMPK and alters mitochondrial energy demand. John explains...

5 Aug 22min

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