Free Radicals
In Our Time1 Nov 2018

Free Radicals

Melvyn Bragg and guests discuss the properties of atoms or molecules with a single unpaired electron, which tend to be more reactive, keen to seize an electron to make it a pair. In the atmosphere, they are linked to reactions such as rusting. Free radicals came to prominence in the 1950s with the discovery that radiation poisoning operates through free radicals, as it splits water molecules and produces a very reactive hydroxyl radical which damages DNA and other molecules in the cell. There is also an argument that free radicals are a byproduct of normal respiration and over time they cause an accumulation of damage that is effectively the process of ageing. For all their negative associations, free radicals play an important role in signalling and are also linked with driving cell division, both cancer and normal cell division, even if they tend to become damaging when there are too many of them.

With

Nick Lane Professor of Evolutionary Biochemistry at University College London

Anna Croft Associate Professor at the Department of Chemical and Environmental Engineering at the University of Nottingham

And

Mike Murphy Professor of Mitochondrial Redox Biology at Cambridge University

Producer: Simon Tillotson

Episoder(1082)

Politics in the 20th Century

Politics in the 20th Century

Melvyn Bragg talks to Gore Vidal and Alan Clarke about the future of the nation-state; is the concept dead and buried? And what is the relationship between politics and morality - have salaciousness and self-righteousness taken over where seriousness of intent and a strong nerve left off, or was it ever thus? With Gore Vidal, American writer, commentator and author of The Smithsonian Institution; Alan Clarke, historian, politician and author of The Tories: Conservatives and the Nation State, 1922-97.

22 Okt 199828min

War in the 20th Century

War in the 20th Century

In the first programme of a new series examining ideas and events which have shaped thinking in philosophy, religion, science and the arts, Melvyn Bragg and guests discuss warfare and human rights in the 20th century. He talks to Michael Ignatieff about the life of one of the 20th century’s leading philosophers, Isaiah Berlin, and to Sir Michael Howard about the 20th century will be remembered; as a century of progress or as one of the most murderous in history. When we see pictures on television of starving people in war torn areas most of us feel we must ‘do’ something. Where does the feeling that we are in some way responsible for our fellow human beings originate historically? How has technology affected the concept of the Just War? And what are the prospects for world peace as we enter the next century? With Michael Ignatieff, writer, broadcaster and biographer of Isaiah Berlin; Sir Michael Howard, formerly Regius Professor of History, Oxford University and joint editor of the new Oxford History of the Twentieth Century.

15 Okt 199827min

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