Nature Podcast11 Okt 2023

Gene edits move pig organs closer to human transplantation

In this episode:

00:46 Engineered pig kidneys show transplantation promise

Kidneys from genetically-engineered miniature pigs have been transplanted into non-human primates, in some cases keeping the animals alive for more than a year. Using CRISPR, a team made dozens of edits to the pig genome to prevent the monkeys’ immune system from attacking the organs. They also removed pig retrovirus genes that could represent an infection risk. These steps are necessary if pig organs are to be used in human transplants, something many clinicians and researchers think will be needed to overcome a critical shortage of organs for transplantation.

Research article: Anand et al.

News and Views: Pig-to-primate organ transplants require genetic modifications of donor

Nature News: The most-complex gene edits yet move pig organs closer to human transplant

09:02 Research Highlights

How babies’ nasal immune systems could explain why they tend to have mild cases of COVID-19, and the molecular ‘glue’ that allows 3D printing with challenging materials.

Research Highlight: How the littlest children stop SARS-CoV-2 in its tracks

Research Highlight: 3D printing tackles tricky materials with help from tiny crystals

11:35 Briefing Chat

This time, the discovery that the human brain uses one system for estimating whether a group contains four or fewer items, and a different one for when there are five or more. Plus, we discuss how researchers fixed the Euclid telescope’s wobbles.

Nature News: Your brain finds it easy to size up four objects but not five — here’s why

Nature News: ‘Immense relief’: Universe-mapping Euclid telescope fixes problem that threatened mission

Subscribe to Nature Briefing, an unmissable daily round-up of science news, opinion and analysis free in your inbox every weekday.

Hosted on Acast. See acast.com/privacy for more information.

Denne episoden er hentet fra en åpen RSS-feed og er ikke publisert av Podme. Den kan derfor inneholde annonser.

Episoder(926)

Briefing Chat: The Bunsen burner myth that turns out to be just hot air

Nature staff discuss an AI tool that can assess the impact of nine billion mutations — plus, how the Bunsen burner’s reputation for sterilization may be based on tradition alone.00:21 Deepmind’s new t...

11 Sep 15min

Phone tutoring boosts math scores when schools are forced to close

In this episode:00:46 How telephone teaching could boost education during school shutdownsNature: Pick up the phone! Phone calls with tutors keep kids learning when schools shut down11:42 Research Hig...

9 Sep 21min

Briefing Chat: How 1,000 pairs of buried underpants helped measure soil health

In this episode:00:21 Our picks of this year’s Ig Nobel prizesNature: Buried underpants and a new definition of kissing win 2026 Ig Nobel prizes07:47 Massive xenon experiment detects tantalizing hint ...

4 Sep 12min

Audio long read: Could mending damaged DNA prolong life?

Scientists are amassing evidence that unrepaired or poorly repaired DNA damage underlies many of the hallmarks of ageing. This has led to research into whether boosting DNA repair can keep people heal...

2 Sep 18min

Briefing Chat: How Dolly Parton left her mark on science

In this episode:00:18 Researchers celebrate Dolly Parton's contributions to scienceNature: Dolly Parton dies aged 80 — researchers celebrate her contributions to science08:40 Phase III trial of melano...

28 Aug 14min

Highest-ever ocean temperatures recorded as El Niño intensifies

Why extreme temperatures are expected to weaken ocean carbon sinks — plus, how mitochondrial injections could treat vision loss.00:46 The world’s oceans reach a record temperatureNature: Ocean tempera...

26 Aug 19min

Briefing Chat: New narcolepsy drug could unlock host of novel brain therapies

Nature staff discuss how an FDA-approved drug for narcolepsy could have promise beyond the condition, and the longest-lived human brain organoids yet.00:28 The promise of a new narcolepsy drugNature: ...

21 Aug 12min

A black hole's spin could finally be measured by a high-speed star

Star orbiting close to Sagittarius A* could reveal its spin — plus, how exoskeletons might change the way humans move.00:46 The star that could reveal a black hole’s spinResearch article: Dayem et al....

19 Aug 29min