Orphan Drugs
99% Invisible14 Nov 2018

Orphan Drugs

We chronicle the epic struggle to get drugs that treat very rare diseases on the market, and the unintended consequence of that fight, which affected the cost of all kinds of drugs. This is a strange story that involves a hit 70s TV show, a fake march on Washington, a courageous advocate, a carnival concessions wholesaler, and a new drug law that helped a lot of people, made drug companies billions of dollars, and opened a whole can of worms.

Adapted from the new podcast An Arm and a Leg by Dan Weissmann

Orphan Drugs

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Episoder(752)

Milk Carton Kids

Milk Carton Kids

On a Sunday morning in 1982, in Des Moines, Iowa, Johnny Gosch left his house to begin his usual paper route. A short time later, his parents were awakened by a phone call–it was a neighbor—their paper hadn’t come. When … Continue reading → Subscribe to SiriusXM Podcasts+ to listen to new episodes of 99% Invisible ad-free and a whole week early. Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

15 Sep 201516min

Reefer Madness

Reefer Madness

There are around 6,000 cargo vessels out on the ocean right now, carrying 20,000,000 shipping containers, which are delivering most of the products you see around you. And among all the containers are a special subset of temperature-controlled units known … Continue reading → Subscribe to SiriusXM Podcasts+ to listen to new episodes of 99% Invisible ad-free and a whole week early. Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

9 Sep 201514min

Bathysphere

Bathysphere

In 1860, a chance find at sea forever changed our understanding of marine habitats, sparking an unprecedented push to explore a new world of possibilities far below the surface of our planet’s oceans. Deep sea life, previously thought possible down … Continue reading → Subscribe to SiriusXM Podcasts+ to listen to new episodes of 99% Invisible ad-free and a whole week early. Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

2 Sep 201521min

The Great Restoration

The Great Restoration

Stirling, Scotland is the home of Stirling Castle, which sits atop a giant crag, or hill, overlooking the whole town of Stirling. There has been a castle on that hill since the 12th century at least, and maybe before, but … Continue reading → Subscribe to SiriusXM Podcasts+ to listen to new episodes of 99% Invisible ad-free and a whole week early. Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

26 Aug 201529min

Lawn Order

Lawn Order

In communities across America, lawns that are brown or overgrown are considered especially heinous. Elite squads of dedicated individuals have been deputized by their local governments or homeowners’ associations to take action against those whose lawns fail to meet community … Continue reading → Subscribe to SiriusXM Podcasts+ to listen to new episodes of 99% Invisible ad-free and a whole week early. Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

19 Aug 201516min

Hard to Love a Brute

Hard to Love a Brute

No matter which James Bond actor is your favorite, it’s undeniable that the Sean Connery films had the best villains. There’s Blofeld, who turned cat-stroking into a thing that super-villains do, and then there’s Goldfinger—Bond’s flashiest nemesis. Fun fact: the … Continue reading → Subscribe to SiriusXM Podcasts+ to listen to new episodes of 99% Invisible ad-free and a whole week early. Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

12 Aug 201516min

The Sunshine Hotel

The Sunshine Hotel

The Bowery, in lower Manhattan, is one of New York’s oldest neighborhoods. It’s been through a lot of iterations. In the 1650s, a handful of freed slaves were the neighborhood’s first residents. At the time, New York was still a … Continue reading → Subscribe to SiriusXM Podcasts+ to listen to new episodes of 99% Invisible ad-free and a whole week early. Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

5 Aug 201526min

From the Sea, Freedom

From the Sea, Freedom

In 1933, delegates from the United States and fourteen other countries met in Montevideo, Uruguay to define what it means to be a state. The resulting treaty from the Montevideo Convention established four basic criteria for statehood—essentially, what is required … Continue reading → Subscribe to SiriusXM Podcasts+ to listen to new episodes of 99% Invisible ad-free and a whole week early. Start a free trial now on Apple Podcasts or by visiting siriusxm.com/podcastsplus. Hosted by Simplecast, an AdsWizz company. See pcm.adswizz.com for information about our collection and use of personal data for advertising.

29 Jul 201518min

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