1005: David Fajgenbaum | Leveraging AI to Cure Rare Diseases

Aimen Dean (@AimenDean) was once one of al-Qaeda’s most respected bomb-makers who swore allegiance to Osama bin Laden himself. He eventually switched sides and spent eight years as an MI6 spy trying t...

28 Jul 20201h 25min

You and the spouse moved in with your father-in-law to emotionally support him when your mother-in-law passed away, but it's difficult to relax or work from home on a foldout bed in the dining room. H...

24 Jul 202047min

Neal Brennan (@nealbrennan) is a comedy writer/producer/director, co-creator of Chappelle's Show, host of the How Neal Feel podcast, and is featured in his own live standup solo show 3 Mics at Netflix...

23 Jul 202054min

Blake Mycoskie (@BlakeMycoskie) is the philanthropic founder of TOMS Shoes, author of Start Something That Matters, and co-founder of wellness subscription box service Madefor (get 20 percent off by u...

21 Jul 202057min

You know that your father, who has a history of cheating on your mother, is currently having an affair with a family "friend." How should you deal with your cheating dad in a way that won't destroy wh...

17 Jul 202043min

Steven Johnson (@stevenbjohnson) is the best-selling author of 11 books on the intersection of science, technology, and personal experience, including Farsighted: How We Make the Decisions That Matter...

16 Jul 20201h 7min

Randolph Nesse (@randynesse) is the founding director of the Center for Evolution Medicine at Arizona State University and author of Good Reasons for Bad Feelings: Insights from the Frontier of Evolut...

14 Jul 20201h 13min

Because of the economic downturn, you're forced to lay off someone who gave up a lot to accept the job on your recommendation. How do you fire someone you care about? We'll tackle this and more here o...

10 Jul 202048min