Opioid agonist treatment, drug related deaths and dynamic models with Matt Hickman
Addiction Audio14 Aug 2022

Opioid agonist treatment, drug related deaths and dynamic models with Matt Hickman

In this episode, Professor Matt Hickman talks about using population modelling to identify the population implications of Opioid Agonist Treatment (OAT). He covers the impact that OAT has on drug-related deaths and other causes of mortality as well as how models can be used to explore what mortality rates would have been without OAT in New South Wales, Australia.


Professor Hickman talks about their findings that, without OAT, the number of overdose deaths would have been 50% higher.


“So, what we were trying to do in this study was to model the counter-factual of how many deaths there would be if there hadn’t been any opioid agonist treatment. In theory the ideal model would be a trial in which you have OAT versus no OAT in a population, now clearly that’s unethical and can’t be done.”


He also talks about how the research team set up a dynamic model that they used to explore the data, matching incarceration and OAT records. They then used those data alongside findings from systematic reviews to model the hypothetical impact of OAT on a real population.


“We’ve done models before, theoretical models which say ‘if we increase the opioid agonist treatment programme and we increase duration at a certain point what impact would that have?’ but that’s rarely based on actual real data. So …there’s modelling and there’s modelling, and this model is based on real empirical data and we think that gives it a bit more credence”.


Original paper here: Modeling the population-level impact of opioid agonist treatment on mortality among people accessing treatment between 2001 and 2020 in New South Wales, Australia by Antoine Chaillon and colleagues. Published in Addiction (2022)

Hosted on Acast. See acast.com/privacy for more information.

Episoder(119)

The future of e-cigarette research with Monserrat Conde

The future of e-cigarette research with Monserrat Conde

In this episode, Dr Chloe Burke talks to Dr Monserrat Conde, a researcher at the Nuffield Department of Primary Care Sciences, University of Oxford, UK. The interview covers a short report on the resu...

13 Mar 15min

Psilocybin's potential in treating methamphetamine use disorder with Jonathan Brett

Psilocybin's potential in treating methamphetamine use disorder with Jonathan Brett

In this episode, Dr Elle Wadsworth talks to Professor Jonathan Brett, a senior consultant at St. Vincent’s Hospital, Sydney, clinical director of the Psychiatry and Non-Prescription Drug and Alcohol U...

6 Mar 19min

Ultra-processed food addiction in older US adults with Lucy Loch

Ultra-processed food addiction in older US adults with Lucy Loch

In this episode, Dr Tsen Vei Lim speaks to Lucy Loch, a doctoral candidate in the Department of Psychology at the University of Michigan, US. The interview covers Lucy’s research article on ultra-proc...

27 Feb 15min

Intersectionality in smoking cessation with Jonathan Bricker

Intersectionality in smoking cessation with Jonathan Bricker

In this episode, Annika Theodoulou speaks to Professor Jonathan Bricker, a Professor of Public Health at the Fred Hutchinson Cancer Research Center and Affiliate Professor of Psychiatry at the Univers...

20 Feb 17min

Estimating risk of cannabis use disorder using standard THC units with Rachel Lees Thorne and Tom Freeman

Estimating risk of cannabis use disorder using standard THC units with Rachel Lees Thorne and Tom Freeman

In this episode, Dr Elle Wadsworth talks to Dr Rachel Lees Thorne, a postdoctoral research associate and Professor Tom Freeman, a professor of psychology, both from the Addiction and Mental Health Gro...

13 Feb 16min

Smoking cessation among adults with substance use problems with Olufemi Erinoso and Jennifer Pearson

Smoking cessation among adults with substance use problems with Olufemi Erinoso and Jennifer Pearson

In this episode, Dr Zoe Swithenbank speaks to Dr Olufemi Erinoso, a postdoctoral fellow at the Massachusetts General Hospital and Dr Jennifer Pearson, an Associate Professor in the School of Public He...

6 Feb 18min

Psilocybin therapy for alcohol use disorder and depression with Amandine Luquiens

Psilocybin therapy for alcohol use disorder and depression with Amandine Luquiens

In this episode, Dr Tsen Vei Lim speaks to Professor Amandine Luquiens, a psychiatrist and addiction specialist at the University of Montpellier and the Addiction Department of Nîmes University Hospit...

30 Jan 15min

Stress and online social networks with Annica Kessling and Elisa Wegmann

Stress and online social networks with Annica Kessling and Elisa Wegmann

In this episode, Dr Tsen Vei Lim speaks to Dr Elisa Wegmann and Annica Kessling, a post-doctoral research fellow and a PhD student at the University of Duisburg-Essen, Germany. The interview covers An...

23 Jan 20min

Populært innen Vitenskap

fastlegen
rekommandert
tingenes-tilstand
sinnsyn
forskningno
rss-rekommandert
liberal-halvtime
smart-forklart
jss
tomprat-med-gunnar-tjomlid
villmarksliv
fjellsportpodden
rss-paradigmepodden
dekodet-2
pod-britannia
psykopoden
rss-overskuddsliv
tidlose-historier
aldring-og-helse-podden
nevropodden