Fentanyl, poly-substance use and the US opioid epidemic with Joseph Friedman
Addiction Audio13 Sep 2023

Fentanyl, poly-substance use and the US opioid epidemic with Joseph Friedman

Ben Scher talks to Dr Joseph Friedman about his research on fentanyl overdoses. Joseph explains the four waves of opioid overdoses in the US and how opiate and opioid overdoses have changed.


They discuss how patterns of poly-substance use are different across the US and how the combination of fentanyl and methamphetamines is become more prevalent across states. Along with the challenges of standardising results when coroners’ reports vary across the US.


One of the main takeaways here is just understanding that poly-substance drug overdose is really becoming the norm….The percent of US overdose deaths involving both fentanyl and stimulants in 2010 was 0.6% so one in every 200 overdose deaths and by 2021 it rose to one-third of all [overdose] deaths.


Original article: Charting the Fourth Wave: Geographic, Temporal, Race/Ethnicity, and Demographic Trends in Polysubstance Fentanyl Overdose Deaths in the United States, 2010-2021 by Joseph Friedman and colleagues. Published in Addiction (2023)

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