#226 - How do weight-loss medications affect metabolic health? And will Ozempic and other GLP-1s actually solve the obesity crisis? | Dr. Rob Lustig & Dr. Casey Means

#226 - How do weight-loss medications affect metabolic health? And will Ozempic and other GLP-1s actually solve the obesity crisis? | Dr. Rob Lustig & Dr. Casey Means

Medications, such as Ozempic, Wegovy, and more, have become increasingly popular for weight loss. These drugs are glucagon-like peptide 1 (GLP-1) receptor agonists, and they mimic a hormone that, among other things, tells the brain a person is full so they eat less. But are they safe, and do they help improve metabolic health? Dr. Rob Lustig and Dr. Casey Means discuss these weight-loss drugs and their effects on the body, and why such medications likely won’t solve the obesity crisis, for which the food industry is culpable.


Sign Up to Get Your Free Ultimate Guide to Glucose: https://levels.link/wnl


🎙 What Rob Lustig, MD, & Casey Means, MD, discuss:

(06:10) — The mechanisms of action for weight-loss medications

(09:01) — Dr. Casey Means shares her perception of the popularity of GLP-1 medications

(13:12) — GLP-1 RAs lead to fat loss but also muscle loss

(18:05) — Do GLP-1 RAs improve metabolic health?

(20:43) — Dr. Lustig discusses the high cost of GLP-1 RAs

(27:47) — Dr. Lustig makes the case for fixing the food problem

(35:46) — How can patients use GLP-1 RAs as a jumpstart?

(44:20) — Dr. Lustig shares his concerns about the use of GLP-1 RAs in children

Transcripts & Show Notes

Levels helps you see how food affects your health, empowering you with the tools needed to achieve health goals and improve healthspan. Levels Members gain access to the Levels app and continuous glucose monitors (CGMs), providing real-time feedback on how diet and lifestyle choices impact your metabolic health.

Look for new shows every month on A Whole New Level, where we have in-depth conversations with thought leaders about metabolic health.


🔗 Helpful links:

Watch the conversation: https://youtu.be/AKNnxKAaONc

📲 Connect:

Find us on YouTube: https://youtube.com/levelshealth?sub_confirmation=1

Episoder(291)

#261 - Uric acid-raising foods to avoid for metabolic, gut, and overall health | Dr. David Perlmutter & Dr. Casey Means

#261 - Uric acid-raising foods to avoid for metabolic, gut, and overall health | Dr. David Perlmutter & Dr. Casey Means

High uric acid can cause gout, but it’s also a marker for worsened metabolic health and gut health and a contributor to neurodegenerative diseases, such as Alzheimer’s. Consumption of purines can lead...

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#260 - Why high insulin levels drive fat storage and weight gain and what you can do | Dr. Robert Lustig & Ben Grynol

#260 - Why high insulin levels drive fat storage and weight gain and what you can do | Dr. Robert Lustig & Ben Grynol

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#259 - What being ‘postdiabetic,’ rather than prediabetic, means and how to get there | Eric Edmeades & Ben Grynol

#259 - What being ‘postdiabetic,’ rather than prediabetic, means and how to get there | Eric Edmeades & Ben Grynol

Before someone develops type 2 diabetes, they go through a prediabetic stage. But if someone is reversing their diabetes and is trending toward better glucose levels or even optimal levels, they are p...

4 Jul 20241h 1min

#258 - What are glucose and insulin and why do they matter for health? | Dr. Robert Lustig & Ben Grynol

#258 - What are glucose and insulin and why do they matter for health? | Dr. Robert Lustig & Ben Grynol

Excess glucose from food gets stored as fat. And our insulin response drives that fat storage. The goal is for the pancreas to release less insulin but for the body to have a healthy response to it. D...

20 Jun 202432min

#257 - Join the “Good Energy” Levels book club and take charge of your health | Dr. Casey Means & Dr. Robert Lustig

#257 - Join the “Good Energy” Levels book club and take charge of your health | Dr. Casey Means & Dr. Robert Lustig

Why are we spending more on health care every year, yet people are getting sicker? “Good Energy,” a book by Casey Means, MD, details how you can take your health into your own hands with the power of ...

14 Jun 20241h 4min

#256 - How quickly can you change your metabolic health and how long does it last? | Dr. Robert Lustig & Ben Grynol

#256 - How quickly can you change your metabolic health and how long does it last? | Dr. Robert Lustig & Ben Grynol

About 93% of people in the United States are not metabolically healthy. But metabolic health can be improved quickly and over time with lifestyle changes. Dr. Robert Lustig and Ben Grynol discuss what...

6 Jun 202410min

#255 - Why you might be a lean mass hyper-responder if you go keto but have high cholesterol | Dave Feldman, Dr. Nick Norwitz & Dr. Dominic D’Agostino

#255 - Why you might be a lean mass hyper-responder if you go keto but have high cholesterol | Dave Feldman, Dr. Nick Norwitz & Dr. Dominic D’Agostino

A lean mass hyper-responder is someone with high LDL and HDL cholesterol and low triglycerides. They are often lean and healthy people who present with strange and alarming lipid numbers after going o...

31 Mai 20241h 40min

#254 - The writing of ‘Good Energy,’ your guide to taking charge of your metabolic health | Dr. Casey Means & Mike Haney

#254 - The writing of ‘Good Energy,’ your guide to taking charge of your metabolic health | Dr. Casey Means & Mike Haney

Writing an evidence-based nonfiction book requires time, dedication, and a true passion for the content. Dr. Casey Means and her brother Calley Means joined forces to create their book “Good Energy: T...

14 Mai 20241h 24min

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