#104: Are Psychedelic Drugs the Next Medical Breakthrough?

#104: Are Psychedelic Drugs the Next Medical Breakthrough?

Martin Polanco (@Martin_Polanco7), M.D., is the founder and program director of Crossroads Treatment Center, based in Rosarito, Mexico. Crossroads specializes in helping patients conquer powerful addictions (heroin, cocaine, etc.) by using the African hallucinogen ibogaine and 5-MeO-DMT, also referred to as “the God molecule.” Martin's areas of expertise also include addiction medicine and therapeutic neurotechnologies. Dan Engle (@drdanengle), M.D., is a psychiatrist and neurologist, who combines functional medicine with integrative psychiatry to enhance regenerative health and peak performance. His prior and relevant experience includes traumatic brain injury (TBI) and working in the Peruvian jungle with plant medicines such as ayahuasca. In this episode, we step outside the lines of traditional medicine to discuss impulse control, introspection, and self-awareness through the use of powerful psychedelic and hallucinogenic agents like iboga, ibogaine and 5-MeO-DMT. We also discuss flotation tanks, which can simulate or even replicate many of the benefits that can result from the use of psychedelic and psychotropic agents. So you don't have to be willing to experiment with these medicines to receive something valuable from this episode. If you are interested in optimizing your psychological performance, emotional control and exploring alternative medicine, then this episode is for you. Enjoy! Show notes and links for this episode can be found at www.fourhourworkweek.com/podcast. This podcast is brought to you by TrunkClub. I hate shopping with a passion. And honestly I’m not good at it, which means I end up looking like I'm colorblind or homeless. Enter TrunkClub, which provides you with your own personal stylist and makes it easier than ever to shop for clothes that look great on your body. Just go to trunkclub.com/tim and answer a few questions, and then you'll be sent a trunk full of awesome clothes. They base this on your sizes, preferences, etc. The trunk is then delivered free of charge both ways, so you only pay for clothes that you keep. If you keep none, it costs you nothing. To get started, check it out at trunkclub.com/tim. This podcast is also brought to you by Vimeo Pro, which is the ideal video hosting platform for entrepreneurs. In fact, a bunch of my start-ups are already using Vimeo Pro. WealthFront uses it to explain how WealthFront works. TaskRabbit uses it to tell the company’s story. There are many other names who you would recognize among their customers (AirBnB, Etsy, etc.) Why do they use it? Vimeo Pro provides enterprise level video hosting for a fraction of the usual cost. Features include: Gorgeous high-quality playback with no ads Up to 20 GB of video storage every week Unlimited plays and views A fully customizable video player, which can include your company logo, custom outro, and more You get all this for just $199 per year (that’s only $17 per/mo.). There are no complicated bandwidth calculations or hidden fees. Try it risk-free for 30 days. Just go to Vimeo.com/business to check it out. If you like it, you can use the promo code “Tim” to get 25% off. This is a special discount just for you guys.

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Episoder(862)

#842: The Story Behind EpiPen, The Rise of Food Allergies, and What Doctors Got Wrong

#842: The Story Behind EpiPen, The Rise of Food Allergies, and What Doctors Got Wrong

This time around, we have an experimental format, featuring the first episode of a brand-new podcast launching next week, Drug Story. I rarely feature episodes from other shows, but I think this one i...

30 Des 202558min

#841: Arthur Brooks — Finding The Meaning of Your Life, The Poet's Protocol, The Holy Half-Hour, and Why Your Suffering is Sacred

#841: Arthur Brooks — Finding The Meaning of Your Life, The Poet's Protocol, The Holy Half-Hour, and Why Your Suffering is Sacred

Arthur C. Brooks is a professor at the Harvard Kennedy School and the Harvard Business School, where he teaches courses on leadership and happiness. His next book, The Meaning of Your Life: Finding Pu...

23 Des 20252h 10min

#840: Bill Gurley — Investing in The AI Era, 10 Days in China, and Important Life Lessons from Bob Dylan, Jerry Seinfeld, MrBeast, and More

#840: Bill Gurley — Investing in The AI Era, 10 Days in China, and Important Life Lessons from Bob Dylan, Jerry Seinfeld, MrBeast, and More

Bill Gurley (@bgurley) is a general partner at Benchmark, a leading venture capital firm in Silicon Valley. His new book is Runnin’ Down a Dream: How to Thrive in a Career You Actually Love.This episo...

17 Des 20252h 10min

#839: Dr. Fei-Fei Li, The Godmother of AI — Asking Audacious Questions, Civilizational Technology, and Finding Your North Star

#839: Dr. Fei-Fei Li, The Godmother of AI — Asking Audacious Questions, Civilizational Technology, and Finding Your North Star

Dr. Fei-Fei Li (@drfeifei) is the inaugural Sequoia Professor in the Computer Science Department at Stanford University, a founding co-director of Stanford’s Human-Centered AI Institute, and the co-fo...

9 Des 20251h 18min

#838: The Random Show — The 2–2–2 Rule, The Future of AI, Bioelectric Medicine, Surviving Modern Dating, The Promises of DORAs for Alzheimer’s, and Wisdom from Anthony de Mello

#838: The Random Show — The 2–2–2 Rule, The Future of AI, Bioelectric Medicine, Surviving Modern Dating, The Promises of DORAs for Alzheimer’s, and Wisdom from Anthony de Mello

Welcome to another wide-ranging "Random Show" episode that I recorded with my close friend Kevin Rose (digg.com)!This episode is brought to you by:Qlosi prescription eye drop used to treat age-related...

3 Des 20251h 51min

#837: How to Simplify Your Life in 2026 — New Tips from Derek Sivers, Seth Godin, and Martha Beck

#837: How to Simplify Your Life in 2026 — New Tips from Derek Sivers, Seth Godin, and Martha Beck

As we head into the new year, many of us feel like we’re drowning in invisible complexity. So I wanted to hit pause and ask a simple question: What are 1-3 decisions that could dramatically simplify m...

26 Nov 202532min

#836: The 4-Hour Workweek Principles — 13 Mistakes to Avoid, The Art of Mini-Retirements, and Navigating the Dizziness of Freedom

#836: The 4-Hour Workweek Principles — 13 Mistakes to Avoid, The Art of Mini-Retirements, and Navigating the Dizziness of Freedom

This time around, we have a bit of a different format, featuring the book that started it all for me, The 4-Hour Workweek. Readers and listeners often ask me what I would change or update, but an equa...

19 Nov 20251h 37min

#835: Ben Patrick (KneesOverToesGuy) — 20-Minute Workouts That Produce Wild Results, From Chronic Knee Pain to Dunking Basketballs, Lessons from Charles Poliquin, Bulletproofing the Lower Body, and More

#835: Ben Patrick (KneesOverToesGuy) — 20-Minute Workouts That Produce Wild Results, From Chronic Knee Pain to Dunking Basketballs, Lessons from Charles Poliquin, Bulletproofing the Lower Body, and More

Ben Patrick, better known as “Kneesovertoesguy” (@kneesovertoesguy), is the founder of Athletic Truth Group (ATG), an online and brick-and-mortar training system rooted in rehabilitative strength and ...

12 Nov 20251h 37min

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