Will Taking GH Before Going To Sleep Suppress Your Natural Production Of GH?
More Plates More Dates13 Feb 2020

Will Taking GH Before Going To Sleep Suppress Your Natural Production Of GH?

At supraphysiological dosages, taking GH before going to sleep makes sense because there is a negative feedback loop on the growth hormone (GH)/insulin-like growth factor I (IGF-1) axis. In this study, IGF-1 was constantly infused, and the effect on endogenous GH secretion was assessed [R]. Overall, GH concentrations were suppressed during the rhIGF-I infusion by 85±3%, mainly by attenuating spontaneous GH pulse amplitude (77±4% suppression). The apparent GH pulse frequency was attenuated from 7.8±0.9 to 4.7±0.6 pulses/24h (P= 0.006). IGF-1 is the primary feedback, and the mechanism is similar to what you see with the HPTA axis. When there is enough Testosterone and Estrogen, your body has this mechanism in place to prevent you from making more. The same thing happens with exogenous GH use. When you administer exogenous GH, IGF-1 elevates. When your body recognizes that IGF-1 is elevated, it starts to suppress GH pulse amplitude in a dose dependent manner. If you are using supraphysiological amounts of GH for bodybuilding purposes, you can assume that your natural secretion is greatly inhibited during sleep as this negative feedback loop will prevent your body from secreting GH in your sleep like it normally would. When endogenous GH production is suppressed, administering exogenous GH at times that lipolysis or muscle growth can be optimized is the most logical approach to injection timing. https://youtu.be/8j9MGfQPeXg If fat loss is the goal, then taking GH in a fasted state prior to fasted cardio would be ideal. There is a ceiling on how much GH is needed to maximize lipolysis, so if your dosage exceeds 2 IU per day, then I would advise splitting up that dose into two (or more if needed) different periods of the day with as much time between them as possible. If muscle growth is the goal, GH should still be administered in a pulsatile fashion to mimic endogenous secretions. Topped out stimulation of autocrine IGF-1 in skeletal muscle can be achieved with fairly low dosages of exogenous GH, and administering a higher dose above and beyond that may just be a waste. This is why it would be wise to split up your daily GH dose into multiple administrations if you are using supraphysiological dosages. Learn more about your ad choices. Visit megaphone.fm/adchoices

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Billionaire Investor Reveals The 3 Most Impactful Books He’s Ever Read – Andrew Wilkinson

Billionaire Investor Reveals The 3 Most Impactful Books He’s Ever Read – Andrew Wilkinson

Andrew’s Website & New Book: https://www.neverenough.com/ Andrew’s Social Media: Twitter: https://x.com/awilkinson YouTube: @NeverEnough2024  Instagram: https://www.instagram.com/awilkinson/ LinkedIn: https://www.linkedin.com/in/awilkinson/ ———————————— 📩 My private email list for written articles, exclusive offers, sales & more: https://bit.ly/2mtASGW ———————————— 🦍 https://gorillamind.com/derek (Innovative Pre-Workout, Nootropic, Performance & Health Supporting Formulations) | code "MPMD" for 10% off ⚡ https://gorillamindenergy.com/ (Gorilla Mind's Nootropic Infused Energy Drinks) 💡 https://intelligent.shop/derek (Intelligent Hair Loss Prevention, Fragrance & Skin Care) | code "MPMD" for 10% off ⚕️ Marek Health - My Preventive Medicine & HRT Platform: https://bit.ly/373k791 🧪 Blood Work: https://bit.ly/2wI3k9J | code "MPMD" for 10% off 🧴 The Best Hair Loss Prevention Shampoo: https://bit.ly/3pXu5UB | code "MPMD" for 10% off 🧴 Intelligent Minoxidil - The Most Effective Product For Hair Growth (Fast-Drying/Non-Oily): https://bit.ly/3owib2i | code "MPMD" for 10% off ⚕️ Pharma Grade Hair Loss Treatments: https://bit.ly/3fG20t2 ———————————— Follow Me On ———————————— INSTAGRAM: https://www.instagram.com/moreplatesmoredates/ TWITTER: https://twitter.com/Derek_Fitness SNAPCHAT: https://www.snapchat.com/add/derek-fit TIKTOK: https://www.tiktok.com/@moreplates FACEBOOK: https://www.facebook.com/moreplates/ ———————————— Subscribe To The More Plates More Dates Podcast ———————————— Spotify: https://open.spotify.com/show/4fCcEMCHgEn57wbGqxKniR Apple Podcasts: https://podcasts.apple.com/us/podcast/more-plates-more-dates/id1424766141 ———————————— Learn more about your ad choices. Visit megaphone.fm/adchoices

24 Nov 20245min

Do You Need DHT To Build Muscle?

Do You Need DHT To Build Muscle?

📌 Check out the full video here: https://youtu.be/eNSx4sV-jys ———————————— 📩 My private email list for written articles, exclusive offers, sales & more: https://bit.ly/2mtASGW ———————————— 🦍 https://gorillamind.com/derek (Innovative Pre-Workout, Nootropic, Performance & Health Supporting Formulations) | code "MPMD" for 10% off ⚡ https://gorillamindenergy.com/ (Gorilla Mind's Nootropic Infused Energy Drinks) 💡 https://intelligent.shop/derek (Intelligent Hair Loss Prevention, Fragrance & Skin Care) | code "MPMD" for 10% off ⚕️ Marek Health - My Preventive Medicine & HRT Platform: https://bit.ly/373k791 🧪 Blood Work: https://bit.ly/2wI3k9J | code "MPMD" for 10% off 🧴 The Best Hair Loss Prevention Shampoo: https://bit.ly/3pXu5UB | code "MPMD" for 10% off 🧴 Intelligent Minoxidil - The Most Effective Product For Hair Growth (Fast-Drying/Non-Oily): https://bit.ly/3owib2i | code "MPMD" for 10% off ⚕️ Pharma Grade Hair Loss Treatments: https://bit.ly/3fG20t2 ———————————— Follow Me On ———————————— INSTAGRAM: https://www.instagram.com/moreplatesmoredates/ TWITTER: https://twitter.com/Derek_Fitness SNAPCHAT: https://www.snapchat.com/add/derek-fit TIKTOK: https://www.tiktok.com/@moreplates FACEBOOK: https://www.facebook.com/moreplates/ ———————————— Subscribe To The More Plates More Dates Podcast ———————————— Apple Podcasts: https://podcasts.apple.com/us/podcast/more-plates-more-dates/id1424766141 Spotify: https://open.spotify.com/show/4fCcEMCHgEn57wbGqxKniR ———————————— Learn more about your ad choices. Visit megaphone.fm/adchoices

23 Nov 20245min

The Truth Is Out!? - Imane Khelif's Leaked Medical Report

The Truth Is Out!? - Imane Khelif's Leaked Medical Report

📩 My private email list for written articles, exclusive offers, sales & more: https://bit.ly/2mtASGW ———————————— 🦍 https://gorillamind.com/derek (Innovative Pre-Workout, Nootropic, Performance & Health Supporting Formulations) | code "MPMD" for 10% off ⚡ https://gorillamindenergy.com/ (Gorilla Mind's Nootropic Infused Energy Drinks) 💡 https://intelligent.shop/derek (Intelligent Hair Loss Prevention, Fragrance & Skin Care) | code "MPMD" for 10% off ⚕️ Marek Health - My Preventive Medicine & HRT Platform: https://bit.ly/373k791 🧪 Blood Work: https://bit.ly/2wI3k9J | code "MPMD" for 10% off 🧴 The Best Hair Loss Prevention Shampoo: https://bit.ly/3pXu5UB | code "MPMD" for 10% off 🧴 Intelligent Minoxidil - The Most Effective Product For Hair Growth (Fast-Drying/Non-Oily): https://bit.ly/3owib2i | code "MPMD" for 10% off ⚕️ Pharma Grade Hair Loss Treatments: https://bit.ly/3fG20t2 ———————————— Follow Me On ———————————— INSTAGRAM: https://www.instagram.com/moreplatesmoredates/ TWITTER: https://twitter.com/Derek_Fitness SNAPCHAT: https://www.snapchat.com/add/derek-fit TIKTOK: https://www.tiktok.com/@moreplates FACEBOOK: https://www.facebook.com/moreplates/ ———————————— Subscribe To The More Plates More Dates Podcast ———————————— Apple Podcasts: https://podcasts.apple.com/us/podcast/more-plates-more-dates/id1424766141 Spotify: https://open.spotify.com/show/4fCcEMCHgEn57wbGqxKniR ———————————— #hormones #olympics #boxing ———————————— Learn more about your ad choices. Visit megaphone.fm/adchoices

21 Nov 202417min

The Reason Why Bodybuilders Are Getting Bubble Gut (Palumboism)

The Reason Why Bodybuilders Are Getting Bubble Gut (Palumboism)

📌 Check out the full podcast here: https://youtu.be/JNpgqpyzW98 ———————————— 📩 My private email list for written articles, exclusive offers, sales & more: https://bit.ly/2mtASGW ———————————— 🦍 https://gorillamind.com/derek (Innovative Pre-Workout, Nootropic, Performance & Health Supporting Formulations) | code "MPMD" for 10% off ⚡ https://gorillamindenergy.com/ (Gorilla Mind's Nootropic Infused Energy Drinks) 💡 https://intelligent.shop/derek (Intelligent Hair Loss Prevention, Fragrance & Skin Care) | code "MPMD" for 10% off ⚕️ Marek Health - My Preventive Medicine & HRT Platform: https://bit.ly/373k791 🧪 Blood Work: https://bit.ly/2wI3k9J | code "MPMD" for 10% off 🧴 The Best Hair Loss Prevention Shampoo: https://bit.ly/3pXu5UB | code "MPMD" for 10% off 🧴 Intelligent Minoxidil - The Most Effective Product For Hair Growth (Fast-Drying/Non-Oily): https://bit.ly/3owib2i | code "MPMD" for 10% off ⚕️ Pharma Grade Hair Loss Treatments: https://bit.ly/3fG20t2 ———————————— Follow Me On ———————————— INSTAGRAM: https://www.instagram.com/moreplatesmoredates/ TWITTER: https://twitter.com/Derek_Fitness SNAPCHAT: https://www.snapchat.com/add/derek-fit TIKTOK: https://www.tiktok.com/@moreplates FACEBOOK: https://www.facebook.com/moreplates/ ———————————— Subscribe To The More Plates More Dates Podcast ———————————— Apple Podcasts: https://podcasts.apple.com/us/podcast/more-plates-more-dates/id1424766141 Spotify: https://open.spotify.com/show/4fCcEMCHgEn57wbGqxKniR ———————————— Learn more about your ad choices. Visit megaphone.fm/adchoices

12 Okt 20245min

Creatine Will RAISE Your Natty Genetic Limit For Muscle Growth!? (nobody talks about this)

Creatine Will RAISE Your Natty Genetic Limit For Muscle Growth!? (nobody talks about this)

📌 Third-Party Tested Micronized Creatine Monohydrate: https://bit.ly/47XyJ8S | code "MPMD" for 10% off ———————————— 📩 My private email list for written articles, exclusive offers, sales & more: https://bit.ly/2mtASGW ———————————— 🦍 https://gorillamind.com/derek (Innovative Pre-Workout, Nootropic, Performance & Health Supporting Formulations) | code "MPMD" for 10% off ⚡ https://gorillamindenergy.com/ (Gorilla Mind's Nootropic Infused Energy Drinks) 💡 https://intelligent.shop/derek (Intelligent Hair Loss Prevention, Fragrance & Skin Care) | code "MPMD" for 10% off ⚕️ Marek Health - My Preventive Medicine & HRT Platform: https://bit.ly/373k791 🧪 Blood Work: https://bit.ly/2wI3k9J | code "MPMD" for 10% off 🧴 The Best Hair Loss Prevention Shampoo: https://bit.ly/3pXu5UB | code "MPMD" for 10% off 🧴 Intelligent Minoxidil - The Most Effective Product For Hair Growth (Fast-Drying/Non-Oily): https://bit.ly/3owib2i | code "MPMD" for 10% off ⚕️ Pharma Grade Hair Loss Treatments: https://bit.ly/3fG20t2 ———————————— Follow Me On ———————————— INSTAGRAM: https://www.instagram.com/moreplatesmoredates/ TWITTER: https://twitter.com/Derek_Fitness SNAPCHAT: https://www.snapchat.com/add/derek-fit TIKTOK: https://www.tiktok.com/@moreplates FACEBOOK: https://www.facebook.com/moreplates/ ———————————— Subscribe To The More Plates More Dates Podcast ———————————— Apple Podcasts: https://podcasts.apple.com/us/podcast/more-plates-more-dates/id1424766141 Spotify: https://open.spotify.com/show/4fCcEMCHgEn57wbGqxKniR ———————————— Learn more about your ad choices. Visit megaphone.fm/adchoices

9 Okt 20244min

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The Ideal Protein Intake For Nattys Vs. Steroid Users

📌 Check out the full podcast here: https://youtu.be/IfRbc1E9boM ———————————— 📩 My private email list for written articles, exclusive offers, sales & more: https://bit.ly/2mtASGW ———————————— 🦍 https://gorillamind.com/derek (Innovative Pre-Workout, Nootropic, Performance & Health Supporting Formulations) | code "MPMD" for 10% off ⚡ https://gorillamindenergy.com/ (Gorilla Mind's Nootropic Infused Energy Drinks) 💡 https://intelligent.shop/derek (Intelligent Hair Loss Prevention, Fragrance & Skin Care) | code "MPMD" for 10% off ⚕️ Marek Health - My Preventive Medicine & HRT Platform: https://bit.ly/373k791 🧪 Blood Work: https://bit.ly/2wI3k9J | code "MPMD" for 10% off 🧴 The Best Hair Loss Prevention Shampoo: https://bit.ly/3pXu5UB | code "MPMD" for 10% off 🧴 Intelligent Minoxidil - The Most Effective Product For Hair Growth (Fast-Drying/Non-Oily): https://bit.ly/3owib2i | code "MPMD" for 10% off ⚕️ Pharma Grade Hair Loss Treatments: https://bit.ly/3fG20t2 ———————————— Follow Me On ———————————— INSTAGRAM: https://www.instagram.com/moreplatesmoredates/ TWITTER: https://twitter.com/Derek_Fitness SNAPCHAT: https://www.snapchat.com/add/derek-fit TIKTOK: https://www.tiktok.com/@moreplates FACEBOOK: https://www.facebook.com/moreplates/ ———————————— Subscribe To The More Plates More Dates Podcast ———————————— Apple Podcasts: https://podcasts.apple.com/us/podcast/more-plates-more-dates/id1424766141 Spotify: https://open.spotify.com/show/4fCcEMCHgEn57wbGqxKniR ———————————— Learn more about your ad choices. Visit megaphone.fm/adchoices

7 Okt 20244min

Going Deep On Hair Loss Prevention Drugs With Peter Attia - From Tame To Nuclear

Going Deep On Hair Loss Prevention Drugs With Peter Attia - From Tame To Nuclear

For those who want to get in front of hair loss with the most efficacious treatment options: 🧴 The Best Hair Loss Prevention Shampoo (mild anti-androgenic properties + is just a good shampoo): https://bit.ly/3pXu5UB 🧴 Intelligent Minoxidil | The Most Effective Product For Hair Growth (Fast-Drying/Non-Oily): https://bit.ly/3owib2i 📌 Intelligent Microneedling Pen (significantly enhances Minoxidil results and recruits growth factors): https://bit.ly/2WVuTKY 📌 Intelligent Derma Roller (cheaper option - manual microneedling roller): https://bit.ly/3Pwyaud ⚕️ Pharma Grade Hair Loss Treatments: https://bit.ly/3fG20t2 ———————————— 📌 Check out the full podcast here: https://youtu.be/JNpgqpyzW98 ———————————— 📩 My private email list for written articles, exclusive offers, sales & more: https://bit.ly/2mtASGW ———————————— 🦍 https://gorillamind.com/derek (Innovative Pre-Workout, Nootropic, Performance & Health Supporting Formulations) | code "MPMD" for 10% off ⚡ https://gorillamindenergy.com/ (Gorilla Mind's Nootropic Infused Energy Drinks) 💡 https://intelligent.shop/derek (Intelligent Hair Loss Prevention, Fragrance & Skin Care) | code "MPMD" for 10% off ⚕️ Marek Health - My Preventive Medicine & HRT Platform: https://bit.ly/373k791 🧪 Blood Work: https://bit.ly/2wI3k9J | code "MPMD" for 10% off 🧴 The Best Hair Loss Prevention Shampoo: https://bit.ly/3pXu5UB | code "MPMD" for 10% off 🧴 Intelligent Minoxidil - The Most Effective Product For Hair Growth (Fast-Drying/Non-Oily): https://bit.ly/3owib2i | code "MPMD" for 10% off ⚕️ Pharma Grade Hair Loss Treatments: https://bit.ly/3fG20t2 ———————————— Follow Me On ———————————— INSTAGRAM: https://www.instagram.com/moreplatesmoredates/ TWITTER: https://twitter.com/Derek_Fitness SNAPCHAT: https://www.snapchat.com/add/derek-fit TIKTOK: https://www.tiktok.com/@moreplates FACEBOOK: https://www.facebook.com/moreplates/ ———————————— Subscribe To The More Plates More Dates Podcast ———————————— Apple Podcasts: https://podcasts.apple.com/us/podcast/more-plates-more-dates/id1424766141 Spotify: https://open.spotify.com/show/4fCcEMCHgEn57wbGqxKniR ———————————— Learn more about your ad choices. Visit megaphone.fm/adchoices

6 Okt 202416min

600 MG+ Caffeine Pre-Workout - One Rep Max Bench Press, Deadlift, And Squat Strength

600 MG+ Caffeine Pre-Workout - One Rep Max Bench Press, Deadlift, And Squat Strength

⚡ Gorilla Mode Lightning High-Stim Pre-Workout: https://gorillamind.com/products/gorilla-mode-lightning | code “MPMD” for 10% off ———————————— 📩 My private email list for written articles, exclusive offers, sales & more: https://bit.ly/2mtASGW ———————————— 🦍 https://gorillamind.com/derek (Innovative Pre-Workout, Nootropic, Performance & Health Supporting Formulations) | code "MPMD" for 10% off ⚡ https://gorillamindenergy.com/ (Gorilla Mind's Nootropic Infused Energy Drinks) 💡 https://intelligent.shop/derek (Intelligent Hair Loss Prevention, Fragrance & Skin Care) | code "MPMD" for 10% off ⚕️ Marek Health - My Preventive Medicine & HRT Platform: https://bit.ly/373k791 🧪 Blood Work: https://bit.ly/2wI3k9J | code "MPMD" for 10% off 🧴 The Best Hair Loss Prevention Shampoo: https://bit.ly/3pXu5UB | code "MPMD" for 10% off 🧴 Intelligent Minoxidil - The Most Effective Product For Hair Growth (Fast-Drying/Non-Oily): https://bit.ly/3owib2i | code "MPMD" for 10% off ⚕️ Pharma Grade Hair Loss Treatments: https://bit.ly/3fG20t2 ———————————— Follow Me On ———————————— INSTAGRAM: https://www.instagram.com/moreplatesmoredates/ TWITTER: https://twitter.com/Derek_Fitness SNAPCHAT: https://www.snapchat.com/add/derek-fit TIKTOK: https://www.tiktok.com/@moreplates FACEBOOK: https://www.facebook.com/moreplates/ ———————————— Subscribe To The More Plates More Dates Podcast ———————————— Apple Podcasts: https://podcasts.apple.com/us/podcast/more-plates-more-dates/id1424766141 Spotify: https://open.spotify.com/show/4fCcEMCHgEn57wbGqxKniR ———————————— Learn more about your ad choices. Visit megaphone.fm/adchoices

6 Okt 20243min

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