The Past, Present, and Future of Epigenetics (Joe Fernandez, founder of Active Motif)

The Past, Present, and Future of Epigenetics (Joe Fernandez, founder of Active Motif)

Joe Fernandez, the founder of Active Motif, has played a significant role in the evolution of the biotechnology industry. He’s seen where the industry has been, and he has a good idea where it’s going.

Prior to founding Active Motif in 1999, Joe was a co-founder of Invitrogen where he helped revolutionize molecular cloning with the TOPO TA kit. Joe’s passion for disrupting established workflows by making them easier and more efficient didn’t stop there. With Active Motif, he launched the first ever ChIP kit in 2003, and the company now offers the most complete portfolio of ChIP kits for different workflows and sample types, the highest quality ChIP-validated antibodies, and the most comprehensive and most cited end-to-end Epigenetic Services.

In this interview, we sat down with Joe to learn how he got started in science, what he’s currently excited about, and what he thinks will be the next big thing in epigenetics research.

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Episoder(167)

Taking ChIP from Yeast to ENCODE to Enable Genome-Wide Regulatory Protein Mapping (Peggy Farnham)

Taking ChIP from Yeast to ENCODE to Enable Genome-Wide Regulatory Protein Mapping (Peggy Farnham)

In this episode of the Epigenetics Podcast, we talked with Peggy Farnham from the Keck School of Medicine at USC about her work on establishing the ChIP Method in mammalian cells. In this episode, we ...

29 Jan 29min

Spatial-Omics and Machine Learning in Muscle Stem Cell Repair (Will Wang)

Spatial-Omics and Machine Learning in Muscle Stem Cell Repair (Will Wang)

In this episode of the Epigenetics Podcast, we talked with Will Wang from Sanford Burnham Prebys about his work on muscle stem cell repair, regeneration, and aging, exploring spatial-omics and machine...

15 Jan 55min

The Future of Protein–DNA Mapping (Mitch Guttman)

The Future of Protein–DNA Mapping (Mitch Guttman)

In this episode of the Epigenetics Podcast, we talked with Mitch Guttman from Caltec about ChIP-DIP (ChIP-Done In Parallel). ChIP-DIP is a newly developed approach for high-resolution protein–DNA inte...

18 Des 20251h 2min

Chromatin Modifiers and Their Roles in Brain Development (Fides Zenk)

Chromatin Modifiers and Their Roles in Brain Development (Fides Zenk)

In this episode of the Epigenetics Podcast, we talked with Fides Zenk from the École polytechnique fédérale de Lausanne about her work on transgenerational inheritance in Drosophila and brain organoid...

4 Des 202528min

Region Capture Micro-C and 3D Genome Structure (Anders Sejr Hansen)

Region Capture Micro-C and 3D Genome Structure (Anders Sejr Hansen)

In this episode of the Epigenetics Podcast, we talked with Anders Sejr Hansen from MIT about his work on the impact of 3D genome structures on gene expression, the roles of proteins like CTCF and cohe...

13 Nov 20251h 3min

Reprogramming Cell Identity through Epigenetic Mechanisms (Vincent Pasque)

Reprogramming Cell Identity through Epigenetic Mechanisms (Vincent Pasque)

In this episode of the Epigenetics Podcast, we talked with Vincent Pasque from KU Leuven about his work on the reprogramming of cell identity through epigenetic mechanisms, particularly during early d...

30 Okt 202540min

The Impact of Chromatin Architecture on Alzheimer's and Parkinson's Disease (Ryan Corces)

The Impact of Chromatin Architecture on Alzheimer's and Parkinson's Disease (Ryan Corces)

In this episode of the Epigenetics Podcast, we talked with Ryan Corces from the Gladstone Institutes about his work on the impact of chromatin architecture on Alzheimer's and Parkinson's Disease. The...

16 Okt 202545min

RNA-Mediated Epigenetic Regulation (Mo Motamedi)

RNA-Mediated Epigenetic Regulation (Mo Motamedi)

In this episode of the Epigenetics Podcast, we talked with Mo Motamedi from the Center for Cancer Research at Massachusetts General Hospital about his work on RNA-mediated epigenetic regulation. The I...

2 Okt 202545min

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