The Truth About Ketamine: Depression Cure, Health Fad, or Placebo?

The Truth About Ketamine: Depression Cure, Health Fad, or Placebo?

One week ago, Matthew Perry’s autopsy report came back, finding that the ‘Friends’ actor died from the acute effects of ketamine overdose. His death has sharpened focus on the popular and controversial drug. Ketamine has been hailed as a miracle cure for depression and anxiety, criticized as a VC-fueled fad, and investigated as a placebo. But what is ketamine, what is its history, what do we know about how and why it works, and how could it help hundreds of millions of people with depression and anxiety? Today’s guest is Boris Heifets. He is an assistant professor of anesthesiology at Stanford University and the author of a much talked about and utterly fascinating study on ketamine that came up with a brilliant way to test the effects of ketamine. The study's surprising results raise big questions about not only ketamine, but the curative power of belief. If you have questions, observations, or ideas for future episodes, email us at PlainEnglish@Spotify.com. Host: Derek Thompson Guest: Boris Heifets Producer: Devon Baroldi Learn more about your ad choices. Visit podcastchoices.com/adchoices

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Episoder(391)

A Philosopher’s One-Word Theory for Why the World Feels So Weird

A Philosopher’s One-Word Theory for Why the World Feels So Weird

Why does it feel like everything is more divided and exhausting than it used to be? Philosopher Agnes Callard has a surprisingly simple answer: the unicontext. It's her term for what happens when bill...

14 Jul 58min

How Israel Is Transforming American Politics

How Israel Is Transforming American Politics

Peter Beinart joins Derek to unpack a major shift inside the Democratic Party. As Democratic Socialist-backed candidates notch a string of surprising primary victories, one issue has emerged as a defi...

7 Jul 1h 4min

MEGAPOD: The Most Overrated American Who Ever Lived

MEGAPOD: The Most Overrated American Who Ever Lived

To celebrate America's 250th birthday, Derek is joined for a history draft by three of the country's leading historians: Beverly Gage, H.W. (Bill) Brands, and Richard White. The goal isn't to revisit ...

3 Jul 1h 9min

A Surprising Theory About the Future of War

A Surprising Theory About the Future of War

From the bombing campaigns of World War II to the precision strikes of the modern era, for 80 years air power has defined modern warfare. But today, a new technology is changing the battlefield: drone...

30 Jun 56min

SpaceX, AI Bubble Fears, and The Age of the Trillion-Dollar, Zero-Profit Company

SpaceX, AI Bubble Fears, and The Age of the Trillion-Dollar, Zero-Profit Company

For decades, investors valued companies based on a familiar formula: Grow revenue, earn profits, and reward shareholders. But a new era may be beginning - one where trillion-dollar companies can lose ...

26 Jun 53min

The Iran War Is Ending. Everybody Lost.

The Iran War Is Ending. Everybody Lost.

Four months ago, the U.S. and Israel launched a surprise attack on Iran. Supporters predicted a decisive victory that would curb Iran’s nuclear ambitions and reshape the balance of power in the Middle...

23 Jun 56min

The Donald Trump Corruption Scandal Draft

The Donald Trump Corruption Scandal Draft

What is Donald Trump good at? In his second administration, he promised lower prices, stronger manufacturing, and an end to foreign conflicts. Instead, inflation has risen, blue-collar job growth has ...

19 Jun 1h 8min

The Most Exciting Month of Medical Breakthroughs in Years

The Most Exciting Month of Medical Breakthroughs in Years

For years, scientists worried that medical progress was slowing down. Drug development became more expensive than ever with more complex clinical trials, and even then, many new treatments offered onl...

16 Jun 59min

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