#125 Longevity Pathways in Humans

#125 Longevity Pathways in Humans

What do the longest living organisms have in common? What regulates aging and longevity in humans? Welcome to the Body Mind Empowerment Podcast I'm your host Siim Land and this episode is the first video lecture from my Metabolic Autophagy Master Class. I'm going to talk about the longevity pathways in humans and other species and how to activate them for anti aging. Hallmarks of aging - 05:15 Free radical theory of aging - 06:48 Are antioxidants effective? - 09:13 Hormesis - 10:10 Longevity pathways in humans - 10:45 Insulin/glucagon (blood sugars) - 12:41 IGF-1 - 13:55 Sirtuins - 17:09 Autophagy + caloric restriction - 18:08 mTOR, AMPK, and autophagy explained - 21:50 FOXO proteins - 23:45 Telomeres - 24:25 Summary and habits to implement - 26:14 And much more... Click Here to Get the Metabolic Autophagy Master Class! Here are the links to the podcast on all platforms Link to the Audio Podcast on iTunes and Stitcher Link to the podcast on Spotify Link to the podcast on CastBox Watch the Biohacking Bootcamp Videos on Patreon If you want to support this podcast, then I'd greatly appreciate if you could join my Patreon community. You'll be able to get access to unique worksheets about Body Mind Empowerment, a lot of exclusive videos about my routines, biohacking workshops, and a privilege for your questions on the next Q&A. Click Here to Support the Show on Patreon! Show Notes Link to Article with Studies My NEW BOOK Metabolic Autophagy Metabolic Autophagy Audiobook Metabolic Autophagy Master Class Get the FULL GUIDE to INTERMITTENT FASTING FREE BOOK Get the Metabolic Autophagy Program Keto Adaptation Manual Book Watch the Biohacking Bootcamp Videos on Patreon Use the Code SIIM for a 10% discount on BluBlox Glasses Use the Code redsiim at Redlightrising.co.uk Body Mind Empowerment Handbook Keto Fit Program Keto // IF Program P.S. The HD video recordings of all the Biohacker Summit Tallinn speeches are now released. Incredible information about optimizing your health and well-being. My own speech talks about doing fasting with training for longevity and muscle growth. Check it out! Stay Empowered Siim

Episoder(491)

#460 50 Minutes of Uncomfortable Truths About Fat Loss & Health No One Tells You

#460 50 Minutes of Uncomfortable Truths About Fat Loss & Health No One Tells You

Join our LONGEVITY and ANTI-AGING Skool Community: https://www.skool.com/youthspan-society-9710/Timestamps:00:00 Intro00:58 How I started writing books04:28 Main keys of fat loss diets09:48 Supplements for fat loss10:33 Effects of diet sodas on fat loss13:48 Metformin effects on longevity17:38 How to optimize sleep23:33 Melatonin supplementation26:30 Calories and energy balance shortcomings30:15 Exercise32:25 Siim’s exercise plan38:45 Top tips for longevity based on research46:30 What’s next for me48:15 Advice for my younger selfCJ's YouTube channel: https://www.youtube.com/@shiftwithcj795 Top 15 supplements to take: https://www.youtube.com/watch?v=jrozJ6oMEjo&ab_channel=SiimLand

6 Jul 50min

#459 Q&A: Collagen vs Glycine, How Much Alcohol is Healthy, How to Improve Kidneys, and Much More

#459 Q&A: Collagen vs Glycine, How Much Alcohol is Healthy, How to Improve Kidneys, and Much More

Get Bon Charge (Code SIIM): https://boncharge.com/siimlandTimestamps:00:00 Can you get benefits of collagen with high dose glycine?02:53 High blood sugar levels and inflammation05:03 Why I eat kiwis before bed05:48 How much alcohol is healthy09:15 Can creatine and glycine increase kidney size10:33 Can a daily sauna be too much13:33 Bon Charge sponsorship14:24 Middle path between a perfect routine and realistic routine18:00 Is whey protein overrated19:54 Is mewing and face massage a scam22:40 My non-negotiable fat sources24:30 How to heal kidneys with high creatinine and low eGFR29:24 How to lose last bit of fat on the belly35:41 Routine for tendon injury recovery38:39 HRT after menopause41:01 Key point for face skin rejuvenationOrder my new book: https://www.amazon.com/dp/B0CW1B2XM1

29 Jun 44min

#458 The Forgotten Role of Creatine and Exercise in Depression - Nicholas Fabiano, MD

#458 The Forgotten Role of Creatine and Exercise in Depression - Nicholas Fabiano, MD

Get Bon Charge (Code SIIM): https://boncharge.com/siimlandTimestamps:00:00 Intro00:45 Creatine and depression benefits07:15 Creatine and inflammation08:20 Traumatic brain injury10:53 Bon Charge sponsorship11:45 Creatine and anxiety13:35 Dietary creatine and depression15:00 Exercise and depression16:35 Why exercise improves depression21:00 Depression analogue to diabetes27:25 Why some people get depression whereas others don’t30:05 Different types of exercise for depression34:10 Exercise dependence43:50 Diet and depression49:10 Microplastics and depression55:00 Saffron and depression58:00 How to mitigate rising depression ratesNicholas Fabiano MD Twitter: https://x.com/NTFabiano

20 Jun 1h 6min

#457 Top Oral Peptides for Tissue Regeneration and Healing

#457 Top Oral Peptides for Tissue Regeneration and Healing

Order my new book: https://www.amazon.com/dp/B0CW1B2XM1Timestamps:00:00 Intro00:35 Peptide regulations in Australia and USA06:35 Peptides for repair and recovery10:35 Why Kyal got into peptides12:55 Oral peptides vs injectable ones19:35 BPC gut repair effects25:35 BPC joint effects27:10 The Wolverine stack for joints32:55 Brain peptides42:35 Creatine45:20 Epitalon48:05 Longevity therapeutics50:40 Effects of mold exposure54:45 Muscle building peptides58:10 Paraxanthine and caffeine01:06:25 MagnesiumCode SIIM for 15% off LVLup oral peptides: https://lvluphealth.com/pages/affiliate/siim-land?ref=SIIMLANDTop 15 Supplements: https://www.youtube.com/watch?v=jrozJ6oMEjo&pp=ygUQc2lpbSBsYW5kIDE1IHN1cA%3D%3D

13 Jun 1h 12min

#456 Q&A at Vitalist Bay About Health and Longevity

#456 Q&A at Vitalist Bay About Health and Longevity

Order my new book: https://www.amazon.com/dp/B0CW1B2XM1Timestamps:00:00 Intro00:18 How long do I want to live01:04 What improved my health the most02:46 Do I have a doctor04:15 Figuring out what's true about health09:18 What people get wrong about creatinine10:35 My predictions for longevity in the next 5-20 years12:38 How much do we spend on health tests a year14:25 What we track most frequently15:58 Experiment that caused my health the most harm21:50 How much healthy food do you need to eat28:31 Nutrition rule of thumb for beginners32:00 Protein and longevity38:05 Nootropics we use

7 Jun 43min

#455 The Optimal Plan to Build Muscle & Lose Fat - Menno Henselmans

#455 The Optimal Plan to Build Muscle & Lose Fat - Menno Henselmans

Order my new book: https://www.amazon.com/dp/B0CW1B2XM1Timestamps:00:00 Intro00:16 Surprising new research about muscle growth03:16 Surprising new research about diets08:16 How you need to train to build muscle18:26 Can you build muscle sprinting20:16 Compound lifts vs machines21:26 Do growth hormone and testosterone increase muscle24:26 Functional movements vs machines27:06 Training frequency30:46 Does cardio hinder muscle growth33:11 Weekly workout plan to follow36:46 Rest intervals between sets40:26 How much protein and fat you need47:01 Calorie surplus vs calorie deficit for muscle growth52:21 How many meals are optimal54:26 Body composition supplementsMenno Henselmans YouTube: https://www.youtube.com/@menno.henselmansMenno Henselmans Instagram: https://www.instagram.com/menno.henselmans/My evidence based longevity routine: https://youtu.be/4xkRcfeGDoo

30 Mai 1h

#454 25 Minutes to Make You Healthier Than 95% of People

#454 25 Minutes to Make You Healthier Than 95% of People

Order my new book: https://www.amazon.com/dp/B0CW1B2XM1Join the next conference in Tallinn, Estonia: https://www.hololifesummit.com/Timestamps:00:00 Longevity Intelligence02:30 Lifestyle risk factors08:19 Longevity Horizon11:13 Genetic risk factors15:55 Biomarkers22:19 SummaryMy evidence based longevity routine: https://youtu.be/4xkRcfeGDoo

25 Mai 24min

#453 Nitric Oxide: The Molecule for Better Blood Flow and Longevity

#453 Nitric Oxide: The Molecule for Better Blood Flow and Longevity

Get Bon Charge Infrared Sauna Blanket (Code SIIM): https://boncharge.com/siimlandTimestamps:00:00 Intro00:23 Why is nitric oxide important04:08 Nitric oxide, blood pressure and erectile dysfunction10:58 Bon Charge sponsorship11:48 How to increase nitric oxide13:53 Effects of microbiome on nitric oxide21:53 Exercise and breathing26:53 Sauna29:30 Supplements that increase nitric oxide36:33 Restart your nitric oxide production39:05 Is nitric oxide harmful in excess48:03 Nitric oxide skin benefits51:03 Household items that reduce nitric oxideDr Nathan Bryan Instagram: https://www.instagram.com/drnathansbryan/

16 Mai 59min

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