#359 Reversing Biological Aging and Extending Lifespan - Matt Kaeberlein PhD

Order my new book: https://www.amazon.com/dp/B0CW1B2XM1 Timestamps: 00:29 Introduction 02:43 Question 1: Death and longevity 11:23 Julie’s advice to Siim 12:58 Meeting likeminded people interested in longevity 17:33 Dave getting stem cells 19:33 Rejuvenation Olympics 22:18 How I share evidence 28:53 Longevity as a sport 40:58 How the Rejuvenation Olympics works 48:28 What’s the best biological age clock 53:58 Telomere length 58:31 How long can we make humans live 01:12:52 Panel about exercise routines 01:19:38 Panel about sleep 01:25:52 Panel about nutrition 01:36:44 Panel about supplements 01:46:44 Best low-hanging fruits Adam the host's channel: https://youtube.com/@nopara73?si=7z6gKAq6s5vZTT_T

22 Sep 20241h 51min

Use code SIIM for a 15% discount off Bon Charge: https://boncharge.com/pages/siimland Timestamps: 00:30 Misconceptions about stem cell therapy 04:20 Different types of stem cells 07:10 Bon Charge sponsorship 07:55 Stem cells and aging 09:00 Studies about stem cell anti-aging effects 13:32 FDA regulations regarding stem cells 25:19 How Joy got into stem cells 36:39 Cost of stem cell therapy 43:40 Process of getting umbilical cord stem cells 49:45 Stem cell procedures 57:55 Finding reliable stem cell clinics 01:02:48 Joy Kong's clinic and content Dr Joy Kong YouTube channel: https://www.youtube.com/@JoyKongMD/featured Order my new book: https://www.amazon.com/dp/B0CW1B2XM1

14 Sep 20241h 7min

Code LEAP for 15% off the Longevity Leap Bundle: https://donotage.org/longevity-leap-bundle Timestamps: 00:29 Leigh’s background 06:44 Health benefits of cold exposure and breathwork 09:44 Mammalian dive reflex 11:45 DoNotAge Longevity Leap supplement bundle 13:20 Benefits of breath holds 16:55 How long can you hold your breath for 20:30 Are there benefits to being able to hold your breath for long 25:56 Hyperventilation vs breath holds 34:46 Breathwork exercises for beginners 40:27 How to breathe correctly 45:00 Nasal breathing vs mouth breathing 52:00 How to breathe during exercise 54:45 Leigh’s new book Leigh Ewin's new book: https://www.leighewin.com/leigh-events/p/re-spiritual-awakening-audiobook-pre-order

7 Sep 20241h 1min

Use code SIIM for a 15% discount off Bon Charge: https://boncharge.com/pages/siimland Timestamps: 00:01 Are Too Many Supplements Bad for Organs 03:46 How to Clear Caffeine From the Body 07:00 When Do I Think Longevity Escape Velocity Will Begin 11:05 Bon Charge Sponsorship 11:49 How to Improve Sleep 14:45 What Biomarker I Want to Improve 19:04 mTOR and Longevity 24:05 How to Increase HRV Besides Exercise 26:25 Do I Have Cheat Meals 27:46 Astaxanthin and Testosterone 29:02 Taking 35 Grams of Glycine Per Day 31:09 Thoughts on Pterostilbene for Longevity 32:25 Essential Supplements for Vegans 34:20 Cancer Prevention 35:42 How to Improve Skin Elasticity 36:43 Does Calorie Restriction Decrease Performance Order my new book: https://www.amazon.com/dp/B0CW1B2XM1 Get The Longevity Leap Worksheet: https://www.siimland.co/offers/gX7pV7RF Join my next retreat at a longevity clinic: https://www.siimland.co/retreat

1 Sep 202440min

Get The Longevity Leap Worksheet: https://www.siimland.co/offers/gX7pV7RF Order my new book: https://www.amazon.com/dp/B0CW1B2XM1 Timestamps 00:12 Alexis' background 03:00 What's available for regeneration currently 04:37 Alexis’ 3 step process for longevity medicine – Phase 1 09:30 The Longevity Leap Worksheet 10:09 Phase 2 - cleanup 12:35 Evidence for chelation therapies 13:58 Effects of senolytics 18:20 Phase 3 - regeneration 19:39 Exosomes and stem cells 28:09 Can exosomes extend lifespan 33:25 Peptides 39:08 Restoring melatonin levels 42:13 How many stem cells do you have 45:05 Why don't we live to 120 51:30 Can you remove plaque from arteries 56:10 What supplements Alexis takes 01:12:00 Diet and exercise 01:17:28 After the 3 phase plan Alexis Ortega MD Instagram: https://www.instagram.com/alexis_ortega_md/

24 Aug 20241h 26min

Get my new book The Longevity Leap: https://www.siimland.co/offers/Mo7aiaAh/ Join our next retreat: https://www.siimland.co/retreat Timestamps: 00:40 Joe's 7th time at the clinic 01:25 Utilization of amino acids 09:00 What tests is Joe doing frequently 10:29 My new book The Longevity Leap 11:08 Joe on taking 150 supplements per day 22:02 Why Joe takes so many supplements 28:42 How genetics affects homocysteine 33:12 How Joe started coaching Liver King 36:47 Does everyone in the modern world need supplements 46:15 Genetics Joe Cohen YouTube channel: https://www.youtube.com/@thejoecohenshow

18 Aug 202448min

Use code SIIM for a 15% discount off Bon Charge: https://boncharge.com/pages/siimland Timestamps: 01:00 Senescent Cells and Aging 09:18 Bon Charge Sponsorship 10:00 Immune System Aging 15:08 What Triggers Cell Senescence 18:50 How to Measure Cell Senescence 22:58 Senolytic Supplements and Drugs 35:50 mTOR, Rapamycin and Senescence 38:25 Aging and Autoimmunity 46:00 Recent Study on IL-11 and Life Extension 55:00 Mice Living Pathogen Free in Labs Matt Kaeberlein Optispan YouTube Channel: https://www.youtube.com/@optispan Get my new book The Longevity Leap: https://www.siimland.co/thelongevityleap

11 Aug 20241h

Use code SIIM for a 15% discount off Bon Charge: https://boncharge.com/pages/siimland Timestamps: 00:01 Recommended supplements for people in their 40s? 08:44 Three simplest ways to increase VO2 max 13:45 What will you do in your 30s that makes the biggest bang for your buck that is not exercise? 16:42 How to decrease stress levels? Any breath method? Supplements to deal with it? 19:57 I supplement with omega 3 high dose but I eat many nuts as well. Is my omega 3 wasted? 22:34 If you don’t have a sauna does a very hot shower bring the same or near benefits? 25:11 Does sex help increase longevity? 27:52 How did you do a fat loss phase? Lower carbs or fat? 30:42 I’d like to gain the weight healthy. Do you have any recommendations for the food, training? 34:16 Are you planning to start taking rapamycin? 36:24 When is your next retreat to India cause we’re coming 37:28 How did you lower your LDL? 38:54 Top 5 things that improved your sleep 42:42 What oil do you use to fry your sweet potato fries? 43:41 Thoughts on astaxanthin? Daily dose? 44:44 Do you take novos core supplement? Pre-order my new book: https://www.siimland.co/offers/Mo7aiaAh Join my next retreat at a longevity clinic: https://www.siimland.co/retreat

3 Aug 202447min