Podcast #296: Synthetic Cannabinoids

Podcast #296: Synthetic Cannabinoids

Author: Rachael Duncan, PharmD

Educational Pearls

  • A NEJM study report in July 2016 discussed a situation in New York during which 30 people became "zombie-like" after ingesting synthetic cannabinoids (aka "Spice).
  • The ER managed to coordinate with the CDC to evaluate blood samples from 18 patients who were transported to the hospital.
  • Of those who went to the ER, the mean age was 36.8, many of them were homeless, all of them were male. Mass spectrometry was used to confirm the presence of synthetic cannabinoid in their blood.
  • Compared to normal THC, synthetic cannabinoids have a much lower EC50 and LD50.
  • Spice intoxication presents in a variety of ways -patients may be hyperthermic, combative, delirious and/or seizing.
  • Treatment is supportive, including fluids, cooling, electrolyte management, and sedatives.

References: Adams, A. J., Banister, S. D., Irizarry, L., Trecki, J., Schwartz, M., & Gerona, R. (2017). "Zombie" Outbreak Caused by the Synthetic Cannabinoid AMB-FUBINACA in New York. New England Journal of Medicine, 376(3), 235-242. doi:10.1056/nejmoa1610300

Episoder(1146)

Husband & Wife, Both ER Clinicians, Share Their Experience Having COVID-19

Husband & Wife, Both ER Clinicians, Share Their Experience Having COVID-19

Long time friends of EMM, Aaron and Bree, share their experiences on the frontlines in the ED, coping with COVID, managing anxiety and quarantining with their family.

1 Apr 202036min

COVID-19 Digest: Do NSAIDs Make COVID-19 More Severe? (Recorded 3/30/20, 18:00 MST)

COVID-19 Digest: Do NSAIDs Make COVID-19 More Severe? (Recorded 3/30/20, 18:00 MST)

In the past two weeks, warnings, questions, and misinformation concerning COVID-19 and NSAID use have been spreading...no pun intended..virally. The pace of this evolving pandemic and the equally quic...

31 Mar 202018min

Podcast 552: PE Management and Risk Stratification

Podcast 552: PE Management and Risk Stratification

Contributor: Dylan Luyten, MD Educational Pearls: After you diagnose a pulmonary embolism (PE) via CT or VQ scan, we need to categorize the PE as massive, sub-massive, or just PE to dictate treatment...

30 Mar 20209min

COVID-19 Digest: If You've Had COVID-19, Can You Get it Again? / Convalescent Serum (Recorded 3/26/20, 18:00 MST)

COVID-19 Digest: If You've Had COVID-19, Can You Get it Again? / Convalescent Serum (Recorded 3/26/20, 18:00 MST)

Host: Elizabeth Esty, MD Research By: Elizabeth Esty and Nathan Novotny References: Osumi M. Questions raised over COVID-19 reinfection after Japanese woman develops illness again. The Japan Times. h...

27 Mar 202010min

ER Doc Infected with COVID-19 Shares Experience

ER Doc Infected with COVID-19 Shares Experience

Recorded 3/26/20

27 Mar 202020min

COVID-19: Hydroxychloroquine & Azithromycin / Anosmia / The Aerosolized vs. Droplet Debate (Recorded 3/24/20, 18:00 MST)

COVID-19: Hydroxychloroquine & Azithromycin / Anosmia / The Aerosolized vs. Droplet Debate (Recorded 3/24/20, 18:00 MST)

The circumstances surrounding the COVID-19 virus are quickly evolving and that means that EMM will have to as well. For the foreseeable future, EMM will be releasing COVID-19 updates. In this series, ...

25 Mar 202015min

Podcast 551:  PPIs are Not Benign

Podcast 551: PPIs are Not Benign

Contributor: Don Stader, MD Educational Pearls: PPIs (Proton pump inhibitors) reduce stomach acid levels and are commonly prescribed in patients with GERD or peptic ulcer disease Stopping a PPI after...

23 Mar 20203min

On the Streets #3: COVID-19

On the Streets #3: COVID-19

In this special edition of our On the Streets podcast, we discuss COVID-19 as well as what first responders and emergency providers need to know to keep themselves and their patients safe during this ...

19 Mar 202020min

Populært innen Vitenskap

fastlegen
rekommandert
tingenes-tilstand
jss
rss-rekommandert
liberal-halvtime
villmarksliv
sinnsyn
rss-paradigmepodden
forskningno
fjellsportpodden
nevropodden
rss-nysgjerrige-norge
vett-og-vitenskap-med-gaute-einevoll
diagnose
dekodet-2
smart-forklart
abid-nadia-skyld-og-skam
rss-lundqvist-podden
hva-er-greia-med