Podcast #395:  Aspirin for everyone!

Podcast #395: Aspirin for everyone!

Author: Aaron Lessen, MD

Educational Pearls:

  • In patients without indications for aspirin, three recent studies looked at prevention of several end points in the elderly
  • These showed no benefit in preventing cardiovascular events (stroke, MI, hear failure), disability, or death in elderly
  • These studies also demonstrated higher mortality and increased bleeding risk in patients who were taking aspirin without clear indications

Editor's note: the increased all cause mortality is intriguing - but attributed to an increase in cancer mortality. Unclear why but will be important to see if this trend is seen in other studies.

References:

McNeil JJ, Woods RL, Nelson MR, et al., on behalf of the ASPREE Investigator Group. Effect of Aspirin on Disability-free Survival in the Healthy Elderly. N Engl J Med. 2018 Oct 18;379(16):1499-1508. doi: 10.1056/NEJMoa1800722. Epub 2018 Sep 16. PubMed PMID: 30221596.

McNeil JJ, Woods RL, Nelson MR, et al., on behalf of the ASPREE Investigator Group. Effect of Aspirin on Cardiovascular Events and Bleeding in the Healthy Elderly. N Engl J Med. 2018 Oct 18;379(16):1509-1518. doi: 10.1056/NEJMoa1805819. Epub 2018 Sep 16. PubMed PMID: 30221597.

McNeil JJ, Woods RL, Nelson MR, et al., on behalf of the ASPREE Investigator Group. Effect of Aspirin on All-Cause Mortality in the Healthy Elderly. N Engl J Med. 2018 Oct 18;379(16):1519-1528. doi: 10.1056/NEJMoa1803955. Epub 2018 Sep 16. PubMed PMID: 30221595.

Summary by Travis Barlock, MS4 | Edited by Erik Verzemnieks, MD



Episoder(1147)

Podcast #257: Strangulation

Podcast #257: Strangulation

Educational Pearls Strangulation is common in cases of domestic violence and sexual assault, and it is associated with higher mortality People who have been strangled have a higher rate of stroke due...

4 Okt 20174min

Podcast #256: Fentanyl Ingestion

Podcast #256: Fentanyl Ingestion

Authors: Don Stader, M.D & Rachael Duncan, PharmD BCPS BCCCP Educational Pearls Fentanyl patches may be abused in many ways, including changing the patches more frequently, chewing them, extracting t...

2 Okt 20175min

Deep Dive #6: Bacteriuria and the Elderly

Deep Dive #6: Bacteriuria and the Elderly

Author: Heidi Wald, MD, MSPH Associate Professor of Medicine - University of Colorado School of Medicine, Physician Advisor - Colorado Hospital Association Dr. Heidi Wald explains common misconceptio...

25 Sep 201729min

Podcast #255: Posterior Vitreous Detachment

Podcast #255: Posterior Vitreous Detachment

Author: Erik Verzemnieks, M.D. Educational Pearls Posterior vitreous detachment is the tearing of the lining in the back of of the eye. Patients often present with loss of vision and floaters. Diagno...

22 Sep 20171min

Podcast #254: Myths About Antibiotic Course Length

Podcast #254: Myths About Antibiotic Course Length

Author: Chris Holmes, M.D. Educational Pearls There's little/no data about the necessary length of an antibiotic course, nor has it proven that stopping a course of antibiotics early selects for the ...

20 Sep 20174min

Podcast #253: Total Eclipse of the Eye - Solar Retinopathy

Podcast #253: Total Eclipse of the Eye - Solar Retinopathy

Author: Nick Hatch, M.D. Educational Pearls Photic or solar retinitis occurs when you stare at the sun. The refractive power of the lens of the eye concentrates the light of the sun on the retina, st...

18 Sep 20173min

Podcast #252: Mandible Fractures

Podcast #252: Mandible Fractures

Author: Sam Killian, M.D. Educational Pearls The tongue blade test is done for mandible fractures, which make up 40-60% of facial fractures. The test is done by having the patient bite down on a tong...

15 Sep 20174min

Podcast #251: Cyanide Poisoning

Podcast #251: Cyanide Poisoning

Author: Rachel Beham, PharmD, Advanced Clinical Pharmacist – Emergency Medicine Educational Pearls Cyanide poisoning is suspected in patients who present with lactic acidosis after being trapped arou...

13 Sep 20174min

Populært innen Vitenskap

fastlegen
rekommandert
tingenes-tilstand
rss-rekommandert
jss
liberal-halvtime
villmarksliv
rss-paradigmepodden
forskningno
sinnsyn
fjellsportpodden
pod-britannia
nevropodden
rss-nysgjerrige-norge
tidlose-historier
hva-er-greia-med
diagnose
rss-overskuddsliv
smart-forklart
rss-lundqvist-podden