Podcast # 463: Buproprion Overdose

Podcast # 463: Buproprion Overdose

Author: Erik Verzemnieks, MD

Educational Pearls:

  • Buproprion is used as an antidepressant and for smoking cessation
  • Severe buproprion overdoses can cause seizures and lead to cardiac dysrhythmias
  • Benzodiazepines are treatment of choice for seizures
  • Bicarbonate and Interlipid are also possible treatment options with less evidence

References

Stall N, Godwin J, Juurlink D. Bupropion abuse and overdose. CMAJ. 2014 Sep 16;186(13):1015. doi: 10.1503/cmaj.131534. Epub 2014 Apr 28. PubMed PMID: 24778361; PubMed Central PMCID: PMC4162783.

Balit CR, Lynch CN, Isbister GK. Bupropion poisoning: a case series. Med J Aust. 2003 Jan 20;178(2):61-3. PubMed PMID: 12526723.

Bruccoleri RE, Burns MM. A Literature Review of the Use of Sodium Bicarbonate for the Treatment of QRS Widening. J Med Toxicol. 2016 Mar;12(1):121-9. doi: 10.1007/s13181-015-0483-y. Review. PubMed PMID: 26159649; PubMed Central PMCID: PMC4781799.

Episoder(1146)

Podcast 664: Rabies Prophylaxis

Podcast 664: Rabies Prophylaxis

Contributor: Jared Scott, MD Educational Pearls: 1-3 cases of rabies per year in US with 55,000 people per year receiving rabies prophylaxis 90% of rabies cases come from wildlife, most commonly by ...

27 Apr 20215min

Podcast 663:  Down Syndrome

Podcast 663: Down Syndrome

Contributor:  Alicia Oberle, MD Educational Pearls: Down Syndrome with Trisomy 21 have three copies of chromosome 21 Current birth rates are around 1 in 700 births  Average life span 25 years in 1980...

26 Apr 20213min

UnfilterED #13: Dr. Nadia Tremonti

UnfilterED #13: Dr. Nadia Tremonti

This week's episode features a fascinating conversation with Dr. Nadia Tremonti, medical director for the pediatric palliative care program at Children's Hospital of Michigan in Detroit. Dr. Tremonti ...

22 Apr 20211h 3min

Podcast 662: Droperidol for Sedation

Podcast 662: Droperidol for Sedation

Contributor:  Aaron Lessen, MD Educational Pearls: Droperidol for sedation in agitated patients in the emergency department was studied compared to ziprasidone (Geodon) and lorazepam (Ativan) Double-...

21 Apr 20213min

Podcast 661: Scalded Skin Syndrome

Podcast 661: Scalded Skin Syndrome

Contributor:  Ricky Dhaliwal, MD Educational Pearls: Primarily affects children Caused by staph aureus releasing exotoxins that result in erythema and sloughing of the skin Present with significant ...

20 Apr 20212min

Podcast 660: Rhabdomyolysis

Podcast 660: Rhabdomyolysis

Contributor: Ricky Dhaliwal, MD Educational Pearls: Rhabdomyolysis occurs when high levels of myoglobin are released from dying muscle tissue into the blood Severe levels of myoglobin cause renal in...

19 Apr 20215min

Podcast 659: Racial Bias in Pulse Oximetry

Podcast 659: Racial Bias in Pulse Oximetry

Contributor:  Aaron Lessen, MD Educational Pearls: Study in NEJM looked at occult hypoxemia, when oxygen saturation reads at >92% when the actual saturation is Rate of occult hypoxemia was 3 times h...

14 Apr 20213min

Podcast 658: Febrile Seizures

Podcast 658: Febrile Seizures

Contributor: Peter Bakes, MD Educational Pearls: Febrile Seizure clinical criteria 6 months - 5 years of age Rapid rise in temp No preexisting seizure disorder No other explanation for the seizure...

13 Apr 20214min

Populært innen Vitenskap

fastlegen
rekommandert
jss
tingenes-tilstand
rss-rekommandert
villmarksliv
liberal-halvtime
sinnsyn
forskningno
rss-paradigmepodden
fjellsportpodden
nevropodden
rss-nysgjerrige-norge
diagnose
vett-og-vitenskap-med-gaute-einevoll
abid-nadia-skyld-og-skam
tidlose-historier
dekodet-2
smart-forklart
hva-er-greia-med