Podcast 691: TXA in Head Bleeds

Podcast 691: TXA in Head Bleeds

Contributor: Ricky Dhaliwal, MD

Educational Pearls:

  • CRASH 3 Trial looked at over 12,000 patients with traumatic intracranial bleeds, randomizing patients to a therapy with TXA or standard of care without TXA
  • Dosing was 1 gram over 10 min for loading dose and then an infusion of 1 gram over 8 hours
  • Found Improvement in survival and neurologic outcomes when patient received TXA within 3 hours

References

CRASH-3 trial collaborators. Effects of tranexamic acid on death, disability, vascular occlusive events and other morbidities in patients with acute traumatic brain injury (CRASH-3): a randomised, placebo-controlled trial [published correction appears in Lancet. 2019 Nov 9;394(10210):1712]. Lancet. 2019;394(10210):1713-1723. doi:10.1016/S0140-6736(19)32233-0

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Episoder(1146)

On the Streets #5: Trauma during COVID-19

On the Streets #5: Trauma during COVID-19

Jordan sits down to discuss trauma with Dr. Kaysie Banton, the Trauma Services Medical Director at Level 1 Trauma Center Swedish Medical Center in Englewood, Colorado. In this laid back interview, Dr....

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Podcast 564:  Cardiac Ischemia Management Update

Podcast 564: Cardiac Ischemia Management Update

Contributor: Nick Tsipis, MD Educational Pearls: Recent randomized controlled trial compared early intervention (PCI/CABG) to medical management for those diagnosed with moderate to severe cardiac is...

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Podcast 563:  DC ACs

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Contributor: Nick Hatch, MD Educational Pearls: An AC (acromioclavicular joint) separation in the shoulder is a common traumatic injury XRs can help rule out other injuries as well as help with gradi...

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Host: Elizabeth Esty, MD. Smoking is known to increase both susceptibility and severity of all manner of colds and pneumonias, so you'd think the world's 1.1 billion smokers would be at risk in this p...

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Podcast 562:  COVID-19 Occlusions

Podcast 562: COVID-19 Occlusions

Contributor: Nick Tsipis, MD Educational Pearls: Case series reported 5 cases of generally young and healthy patients with COVID-19 who presented to the ER with acute stroke Now several case series s...

12 Mai 20202min

Podcast 561:  Give Bup

Podcast 561: Give Bup

Contributor: Don Stader, MD Educational Pearls: Buprenorphine has been shown to decrease morbidity and mortality in opioid use disorder Buprenorphine used in naloxone-induced withdrawals can displace...

11 Mai 20204min

COVID-19 Digest: Bacille Calmette-Guérin (BCG) Vaccine for Treating COVID-19

COVID-19 Digest: Bacille Calmette-Guérin (BCG) Vaccine for Treating COVID-19

In the US, few people receive vaccination for tuberculosis (TB), a disease that hasn't been a major killer here for many decades. But while we in the US mostly experience TB as a relatively rare but ...

8 Mai 202014min

Podcast 560:  Imaging in a COVID world

Podcast 560: Imaging in a COVID world

Contributor: Don Stader, MD Educational Pearls: COVID-19 commonly appears as a bilateral patchy infiltrate on chest radiograph, but this is a non-specific finding Sensitivities range from 17-70% f...

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