Podcast 783: LAD Occlusion & Troponin

Podcast 783: LAD Occlusion & Troponin

Contributor: Jared Scott, MD

Educational Pearls:

  • A study randomized 34 healthy patient to have their left anterior descending artery (LAD) occluded by balloon for 0, 15, 30, or 90 seconds
  • Subsequently, cardiac troponins (cTns) and Copeptin were measured every 15 minutes for 3 hours, then every 30 minutes for the next 3 hours
  • 5 conclusions were drawn:
    • Copeptin is not a useful marker of cardiac ischemia
    • cTn may be detected after only 30 seconds of ischemia
    • cTn may be detected in a little as 15 minutes after ischemic event
    • After only 90 seconds of ischemia, cTn levels met threshold for MI
    • Troponin I is a better marker than troponin T as it rises faster and reaches a higher peak
  • Patients very recent or very brief ischemic events may have elevated troponin in the ED

References

Árnadóttir Á, Pedersen S, Bo Hasselbalch R, et al. Temporal Release of High-Sensitivity Cardiac Troponin T and I and Copeptin After Brief Induced Coronary Artery Balloon Occlusion in Humans [published correction appears in Circulation. 2021 Jun 22;143(25):e1116]. Circulation. 2021;143(11):1095-1104. doi:10.1161/CIRCULATIONAHA.120.046574

Summarized by Kirsten Hughes, MS4 | Edited by John Spartz, MD, MPH & Erik Verzemnieks, MD

The Emergency Medical Minute is excited to announce that we are now offering AMA PRA Category 1 credits™ via online course modules. To access these and for more information, visit our website at https://emergencymedicalminute.org/cme-courses/ and create an account.

Donate to EMM today!



Episoder(1145)

Pharmacy Phriday #6: Tik Tok Benadryl Challenge and Diphenhydramine Toxicity

Pharmacy Phriday #6: Tik Tok Benadryl Challenge and Diphenhydramine Toxicity

Contributor: Ruben Marrero-Vasquez, PharmD Educational Pearls: ACEP and FDA have both issued warnings about the viral Tik Tok Benadryl (diphenhydramine) challenge where individuals voluntarily overdo...

1 Jan 20216min

Mental Health Monthly #6: Suicide Assessment

Mental Health Monthly #6: Suicide Assessment

EMM is excited to welcome back the hosts of Millennial Mental Health Channel podcast to explain the key points of a robust suicide assessment in the ED. Dr. Justin Romano is a third year psychiatry re...

30 Des 202016min

Podcast 626: Updated Gonorrhea Treatment

Podcast 626: Updated Gonorrhea Treatment

Educational Pearls: The CDC has made new formal recommendations for treating Gonorrhea due to increasing resistance to Rocephin and Azithromycin. New recommendations: Confirmed gonorrhea: Ceftriaxo...

29 Des 20204min

Podcast 625: High Altitude Cerebral Edema (HACE)

Podcast 625: High Altitude Cerebral Edema (HACE)

Contributor: Tom Seibert, MD Educational Pearls: High altitude cerebral edema (HACE) is the end stage of acute mountain sickness and is diagnosed when patients develop neurologic dysfunction, ataxia,...

28 Des 20202min

Podcast 624: Timing and Tips on Sepsis

Podcast 624: Timing and Tips on Sepsis

Contributor: Don Stader, MD Educational Pearls: Time can be an important factor in outcomes regarding sepsis including mortality Emphasis has grown on early administration of antibiotics and IV fluid...

22 Des 20203min

Podcast 623: Acute Mountain Sickness

Podcast 623: Acute Mountain Sickness

Contributor: Tom Seibert, MD Educational Pearls: Acute Mountain sickness (AMS) can cause headache along with fatigue, nausea, vomiting, insomnia Typically occurs above 6500 feet (not 65,000) in eleva...

21 Des 20204min

Podcast 622: High Altitude Pulmonary Edema (HAPE)

Podcast 622: High Altitude Pulmonary Edema (HAPE)

Contributor: Thomas Seibert, MD Educational Pearls: High Altitude Pulmonary Edema (HAPE) typically occurs 2-4 days after arriving at elevation Symptoms include: Fatigue Dyspnea Cough Treatment in...

15 Des 20204min

Podcast 621: Pediatric Psychosis

Podcast 621: Pediatric Psychosis

Contributor: Aaron Lessen, MD Educational Pearls: Schizophrenia typically doesn't present until age 13 and has a prodrome Prodrome includes months of gradual changes in behavior, starting with negati...

14 Des 20203min

Populært innen Vitenskap

fastlegen
tingenes-tilstand
rekommandert
jss
rss-nysgjerrige-norge
rss-rekommandert
sinnsyn
forskningno
rss-paradigmepodden
villmarksliv
vett-og-vitenskap-med-gaute-einevoll
fjellsportpodden
nordnorsk-historie
smart-forklart
rss-overskuddsliv
diagnose
abid-nadia-skyld-og-skam
aldring-og-helse-podden
pod-britannia
tidlose-historier