#458: The Psychedelic News Hour: New Breakthroughs, Compound Comparisons and Warnings (Psilocybin/LSD/Ayahuasca/N,N-DMT/5-MeO-DMT), Treatment of Trauma, Scalable vs. Unscalable Approaches, Making Sense of “Bad” Trips, and Much More

#458: The Psychedelic News Hour: New Breakthroughs, Compound Comparisons and Warnings (Psilocybin/LSD/Ayahuasca/N,N-DMT/5-MeO-DMT), Treatment of Trauma, Scalable vs. Unscalable Approaches, Making Sense of “Bad” Trips, and Much More

Welcome to another episode of The Tim Ferriss Show, where it is normally my job to deconstruct world-class performers of various types, of all ilks.

In this special episode, the tables are turned. Instead of interviewing someone else, I am interviewed by two experts on several topics I’ve both studied and supported, including psychedelic-assisted psychotherapy and what it can do to heal trauma and—broadly speaking—possible futures for mental health. This audio was recorded on a new show, The Psychedelic News Hour, soon to be a podcast, and I’m in conversation with two people: David Rabin, MD, PhD, (@drdavidrabin), a board-certified psychiatrist and neuroscientist, executive director of The Board of Medicine, and co-founder of Apollo Neuroscience, and Molly Maloof, MD, (@drmolly.co), a physician, Stanford lecturer, and ketamine-assisted psychotherapist.

This episode was recorded on Clubhouse, an app still in private beta and defined by their tagline: “Clubhouse is a space for casual, drop-in audio conversations—with friends and other interesting people around the world.”

One final note: I recorded this on my phone, a necessity for using the app, so the audio quality isn’t studio quality, but it was polished as much as possible. Thank you for understanding, and thanks to everyone who joined and asked thoughtful questions.

This episode is brought to you by the book How to Lead by David Rubenstein. David Rubenstein is one of the visionary founders of The Carlyle Group and host of The David Rubenstein Show, where he speaks to leaders from every walk of life about who they are, how they define "success," and what it means to lead. Jeff Bezos, Richard Branson, Warren Buffet, Bill Gates, Ruth Bader Ginsburg, Phil Knight, Oprah — all of them and more — are featured in his new book, titled How to Lead. This comprehensive leadership playbook illustrates the principles and guiding philosophies of the world’s greatest game-changers. In its pages, you can discover the experts’ secrets to being effective and innovative leaders.

Past podcast guest Walter Isaacson had this to say: "Reading this invaluable trove of advice from the greatest leaders of our time is like sitting in an armchair and listening to the masters reveal their secrets.” Pick up a copy of How to Lead: Wisdom from the World’s Greatest CEOs, Founders, and Game Changers by David Rubinstein in hardcover, ebook, or audio anywhere books are sold.

***

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For show notes and past guests, please visit tim.blog/podcast.

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Past guests on The Tim Ferriss Show include Jerry Seinfeld, Hugh Jackman, Dr. Jane Goodall, LeBron James, Kevin Hart, Doris Kearns Goodwin, Jamie Foxx, Matthew McConaughey, Esther Perel, Elizabeth Gilbert, Terry Crews, Sia, Yuval Noah Harari, Malcolm Gladwell, Madeleine Albright, Cheryl Strayed, Jim Collins, Mary Karr, Maria Popova, Sam Harris, Michael Phelps, Bob Iger, Edward Norton, Arnold Schwarzenegger, Neil Strauss, Ken Burns, Maria Sharapova, Marc Andreessen, Neil Gaiman, Neil de Grasse Tyson, Jocko Willink, Daniel Ek, Kelly Slater, Dr. Peter Attia, Seth Godin, Howard Marks, Dr. Brené Brown, Eric Schmidt, Michael Lewis, Joe Gebbia, Michael Pollan, Dr. Jordan Peterson, Vince Vaughn, Brian Koppelman, Ramit Sethi, Dax Shepard, Tony Robbins, Jim Dethmer, Dan Harris, Ray Dalio, Naval Ravikant, Vitalik Buterin, Elizabeth Lesser, Amanda Palmer, Katie Haun, Sir Richard Branson, Chuck Palahniuk, Arianna Huffington, Reid Hoffman, Bill Burr, Whitney Cummings, Rick Rubin, Dr. Vivek Murthy, Darren Aronofsky, and many more.

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Episoder(860)

#832: The Return of The Lion Tracker — Boyd Varty on The Wild Man Within, Nature’s Hidden Wisdom, and How to Feel Fully Alive

#832: The Return of The Lion Tracker — Boyd Varty on The Wild Man Within, Nature’s Hidden Wisdom, and How to Feel Fully Alive

Boyd Varty is the founder of Track Your Life, which offers a limited number of premium retreats in South Africa’s bushveld, and author of one of my favorite books, The Lion Tracker’s Guide to Life. As...

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#831: Frank Miller, Comic Book Legend — Creative Process, The Dark Knight Returns, Sin City, 300, and Much More

#831: Frank Miller, Comic Book Legend — Creative Process, The Dark Knight Returns, Sin City, 300, and Much More

Frank Miller is regarded as one of the most influential and awarded creators. He began his career in comics in the late 1970s, first gaining notoriety as the artist, and later writer, of Daredevil for...

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#830: Nick Kokonas and Richard Thaler, Nobel Prize Laureate — Realistic Economics, Avoiding The Winner’s Curse, Using Temptation Bundling, and Going Against the Establishment

#830: Nick Kokonas and Richard Thaler, Nobel Prize Laureate — Realistic Economics, Avoiding The Winner’s Curse, Using Temptation Bundling, and Going Against the Establishment

Richard H. Thaler is the 2017 recipient of the Nobel Memorial Prize in Economic Sciences for his contributions to behavioral economics and the Charles R. Walgreen Distinguished Service Professor of Be...

10 Okt 20251h 57min

#829: James Nestor — Breathing Protocols to Reboot Your Health, Fix Your Sleep, and Boost Performance

#829: James Nestor — Breathing Protocols to Reboot Your Health, Fix Your Sleep, and Boost Performance

James Nestor is a science journalist and the author of the international bestseller Breath: The New Science of a Lost Art, with more than three million copies sold in 44 languages.This episode is brou...

30 Sep 20251h 50min

#828: David Senra — How Extreme Winners Think and Win: Lessons from 400+ of History’s Greatest Founders and Investors (Including Buffett, Munger, Rockefeller, Jobs, Ovitz, Zell, and Names You Don’t Know But Should)

#828: David Senra — How Extreme Winners Think and Win: Lessons from 400+ of History’s Greatest Founders and Investors (Including Buffett, Munger, Rockefeller, Jobs, Ovitz, Zell, and Names You Don’t Know But Should)

David Senra is the host of the Founders podcast. For the past nine years, David has intensely studied the life and work of hundreds of history’s greatest entrepreneurs. His new podcast, David Senra, s...

24 Sep 20252h 55min

#827: Pablos Holman — One of The Scariest Hackers I’ve Ever Met

#827: Pablos Holman — One of The Scariest Hackers I’ve Ever Met

Pablos Holman is a hacker and inventor and the author of Deep Future: Creating Technology that Matters, the indispensable guide to deep tech. Previously, Pablos worked on spaceships at Blue Origin and...

16 Sep 20252h 31min

#826: Q&A with Tim — Supplements I’m Taking, Austin vs. SF, Training for Mental Performance, Current Go-To AI Tools, Recovering from Surgery, Intermittent Fasting, and More

#826: Q&A with Tim — Supplements I’m Taking, Austin vs. SF, Training for Mental Performance, Current Go-To AI Tools, Recovering from Surgery, Intermittent Fasting, and More

This episode is a solo Q&A session where I answer a bunch of questions. We covered a ton of ground, from personal health protocols to professional frameworks and creative projects. This episode is bro...

9 Sep 20251h 25min

#825: Dr. Dominic D’Agostino — All Things Ketones, How to Protect the Brain and Boost Cognition, Sardine Fasting, Diet Rules, Revisiting Metformin and Melatonin, and More

#825: Dr. Dominic D’Agostino — All Things Ketones, How to Protect the Brain and Boost Cognition, Sardine Fasting, Diet Rules, Revisiting Metformin and Melatonin, and More

Dr. Dominic D’Agostino (@DominicDAgosti2) is a tenured associate professor in the Department of Molecular Pharmacology and Physiology at the University of South Florida Morsani College of Medicine and...

3 Sep 20251h 54min

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