#419 Dave Pascoe and Julie Gibson Clark Discuss Their Diet, Supplements and Exercise Routines

Use code SIIM for a 15% discount off Bon Charge: https://boncharge.com/pages/siimlan Timestamps: 00:00 What's the unhealthiest thing in my life 08:00 Bon Charge sponsorship 08:55 How to have good kidney markers 16:18 Does niacinamide inhibit SIRT1 18:55 How to optimize shift work 23:54 What routines to keep when you have a deadline 28:07 Is a hot tub the same as sauna 30:00 Alternatives to olive oil 33:35 Does astaxanthin inhibit exercise benefits Order my new book: https://www.amazon.com/dp/B0CW1B2XM1 Get my free supplement list: https://www.siimland.co/supplement-list

22 Nov 202436min

Order my new book: https://www.amazon.com/dp/B0CW1B2XM1 Timestamps: 00:00 Intro 00:35 Raghav’s new study on epigenetic age 04:25 Biological age explained 10:45 How epigenetics affects aging 12:40 Biological age clocks and biomarkers 21:50 Top performers in lowering epigenetic age 32:20 How chronological age affects biological age 35:20 Gene therapies 40:10 Effect of diet and exercise 45:40 What biomarkers affect biological age 49:45 Organ aging 58:00 Final thoughts Raghav Sehgal Twitter: https://twitter.com/rv_sehgal Raghav Sehgal website: https://www.raghav-sehgal.com/

15 Nov 20241h 5min

Use code SIIM for a 15% discount off Bon Charge: https://boncharge.com/pages/siimland Timestamps: 00:00 Intro 01:30 What are peptides and how are they made 07:20 Safety of peptides 12:52 FDA and peptides 18:45 BPC157 31:10 TB500 37:20 Growth hormone peptides 44:20 Longevity peptides, Epitalon, Melanotan 52:35 Fundamentals of lifestyle 56:45 Preparing for peptide protocols Dr Silvana Laith Instagram: https://www.instagram.com/drsilvanalaith/ Noah Laith Instagram: https://www.instagram.com/thestoicbiohacker/ I Took BPC 157 Peptide for 2 Months and Here's What Happened: https://youtu.be/9qc9dhDDDhc Order my new book: https://www.amazon.com/dp/B0CW1B2XM1

6 Nov 20241h 4min

Hello, this is a casual livestream. The list is based on my opinion Order my new book: https://www.amazon.com/dp/B0CW1B2XM1

3 Nov 202451min

Use code SIIM for a 15% discount off Bon Charge: https://boncharge.com/pages/siimland Timestamps: 00:00 Intro 00:32 Bon Charge Sponsorship 01:20 Declining Heart Disease Rates 05:10 Biggest Risk Factors of Heart Disease 10:15 What Is Heart Disease and Atherosclerosis 13:55 When Does Atherosclerosis Begin 20:55 Biggest Risk Factors of Heart Disease 27:55 Role of Genetics in Heart Disease 31:50 High vs Low Lipids 39:40 Managing Your Risk Trajectory Over Time 45:30 Lp(a) 52:30 ApoB vs Cholesterol 57:20 Does HDL Reduce the Risk of Heart Disease 59:35 Homocysteine 01:02:55 Does Too Much Exercise Cause Atherosclerosis 01:09:55 Practical Steps to Heart Disease Prevention 01:15:30 Detecting Calcium in the Arteries 01:20:35 Calcified Hard Plaques vs Non-Calcified Plaques 01:22:45 At What Calcium Score Can You Get a Heart Attack Dr Paddy Barrett Twitter: https://x.com/paddy_barrett Dr Paddy Barrett Substack: https://paddybarrett.substack.com/

26 Okt 20241h 26min

Order my new book: https://www.amazon.com/dp/B0CW1B2XM1 Timestamps: 00:00 Introduction 00:37 Twenty since Aubrey coined the Longevity Escape Velocity 11:13 When will we reach Longevity Escape Velocity 16:45 Slowing down aging vs regeneration 19:44 What breakthroughs we need for longevity escape velocity 24:00 Seven types of aging damage that needs to be repaired 24:37 Loss of cells and stem cells 33:57 Regenerating limbs and organs 36:10 Mitochondrial free radical theory of aging 41:15 Intracellular and Extracellular waste products 47:15 How far is gene therapy now? 49:15 Death resistant cells 53:52 Do you need long telomeres 57:15 Extracellular matrix stiffening and glycation 01:00:48 Biggest breakthroughs in the next 5 years 01:04:30 What to do to live until the longevity escape velocity The Longevity Escape Velocity Foundation: https://www.levf.org/ Aubrey de Grey Twitter: https://x.com/aubreydegrey

17 Okt 20241h 8min

Order my new book: https://www.amazon.com/dp/B0CW1B2XM1 Timestamps: 00:30 Introduction 00:50 What is cancer 04:30 Does everyone have cancer all the time? 06:30 When does cancer become lethal 11:30 Hallmarks of cancer 21:20 Senescent cells vs cancer cells 25:00 Evolutionary purpose of cancer 27:30 Cancer prevention 30:10 Ultra processed food and cancer risk 35:35 Organic vs non-organic food 38:40 What are carcinogens 45:10 Immune function and cancer 48:15 Meat and cancer 51:20 mTOR and cancer 01:02:20 Glucose, Warburg Effect and cancer 01:07:00 Ketones and cancer 01:11:00 Artificial sweeteners 01:16:40 Environmental toxins Dr Joe Zundell YouTube channel: https://www.youtube.com/@dr.joezundell Dr Joe Zundell Instagram: https://www.instagram.com/dr.joezundell/

13 Okt 20241h 26min

Use code SIIM for a 15% discount off Bon Charge: https://boncharge.com/pages/siimland Timestamps: 00:01 Supplements that are bad for the heart 08:45 Will we see someone live to 125 11:56 Bon Charge sponsorship 12:46 Maltodextrin in protein powder 13:59 Hyaluronic acid supplementation and cancer 15:32 Creatine reduces VO2 max 17:55 Limiting factor in losing visceral fat 20:45 Which disease am I most afraid of 25:13 Weighted stretching for muscle growth 28:00 Protein restriction and lifespan 32:22 How to train with joint pain 35:39 How much NAC for 60+ 37:23 How to stimulate appetite 40:47 What's a good VO2 max for women Order my new book: https://www.amazon.com/dp/B0CW1B2XM1 Get The Longevity Leap Worksheet: https://www.siimland.co/offers/gX7pV7RF

5 Okt 202443min