Dementia Researcher Blogs30 Apr 2024

Dr Dylan Williams - The Genetic Culprit Behind Alzheimer's

Dr Dylan Williams, narrates his blog written for the Dementia Researcher website.

In this article Dr Dylan Williams shares his research on the significant role of genetic variation, particularly concerning Apolipoprotein E (apoE), in the development of Alzheimer's disease. Dylan explains that specific isoforms of apoE, identified through genetic research, contribute differentially to the risk of developing this neurodegenerative condition. By focusing on the prevalent and impactful ε3 and ε4 isoforms, he underscores their substantial contribution to the disease, potentially accounting for three-quarters of all cases. This insight not only advances our understanding but also opens new avenues for targeted prevention strategies, demonstrating the power of genetic research in addressing complex diseases like Alzheimer's.

Find the original text, and narration here on our website.

https://www.dementiaresearcher.nihr.ac.uk/blog-the-genetic-culprit-behind-alzheimers/

Dr Dylan Williams is a Principle Research Fellow at University College London. By day Dylan is a molecular epidemiologist investigating the causes of neurodegenerative diseases. Outside work, he is dad to two young children, so he no longer have hobbies. However, he does read spent many hours listening to music and creating playlists & trail running (but only if the weather is nice). @dylan_wi11iams

Enjoy listening? We're always looking for new bloggers, drop us a line. http://www.dementiaresearcher.nihr.ac.uk

This podcast is brought to you in association with Alzheimer's Association, Alzheimer's Research UK, Alzheimer's Society and Race Against Dementia, who we thank for their ongoing support.

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