Effect of therapeutic drug monitoring-based dose optimisation of piperacillin/tazobactam in sepsis patients
Growing evidence suggests that insufficient antibiotic exposure (defined as failure to achieve the pharmacokinetic/pharmacodynamic (PK/PD) target to kill or inhibit the growth of a pathogen) is associ...
2 Mar 202229min
Current practice and evolving concepts in septic shock resuscitation
Clinical and pathophysiological understanding of septic shock has progressed exponentially in the previous decades, translating into a steady decrease in septic shock-related morbidity and mortality. ...
16 Feb 202222min
Non-invasive respiratory support following extubation in critically ill adults
Clinicians use noninvasive respiratory support interventions in the post-extubation period to mitigate the risk of extubation failure. These interventions [noninvasive positive pressure ventilation (N...
2 Feb 202230min
Challenges of renal transplant patients in intensive care
Kidney transplantation is the most common solid organ transplant performed worldwide. New advances in transplant medicine have expanded the indications for kidney transplantation, and nowadays, many k...
28 Jan 202227min
Practicalities of Neuromonitoring
Neuromonitoring is considered a crucial and fundamental process to monitor patients in critical care settings. In this podcast, ESICM NEXT member Denise Battagliani interviews Chiara Robba on the ulti...
21 Jan 202213min
Dexamethasone 12 mg versus 6 mg for patients with COVID-19 and severe hypoxaemia
Systemic corticosteroids decrease mortality in critically ill patients with COVID-19, and the World Health Organization, therefore, recommends dexamethasone 6 mg daily for up to 10 days for patients w...
19 Jan 202214min
Extracorporeal cardiopulmonary resuscitation in adults: evidence and implications
Attempts at improving cardiac arrest outcomes have increasingly included extracorporeal techniques to re-establish circulation. In particular, the application of veno-arterial extracorporeal membrane ...
12 Jan 202216min
Effect of adjunctive vitamin C, glucocorticoids, and vitamin B1 on longer-term mortality in adults with sepsis or septic shock
Metabolic resuscitation is an adjunctive therapy for sepsis and septic shock, which consists of a combination of vitamin C, glucocorticoids, and vitamin B1 or their components. Recently, there has bee...
5 Jan 202212min
