Role of pre-clinical experimentation in intensive care: from ethical to clinical practice
ESICM Talk23 Mar 2022

Role of pre-clinical experimentation in intensive care: from ethical to clinical practice

Preclinical studies precede most clinical trials. They help identify criteria for evaluating human safety, including signs and symptoms that should be monitored closely during early clinical trials.

The importance of these preclinical studies in intensive care medicine starts from developing new surgical procedures, and hands-on training to new medical devices and prescription drugs.

To have more insights into preclinical research and real examples of translation of such research in clinical practice, we interviewed Dr Marcin Osuchowski, an expert in the field.

Help us review our educational podcasts! Complete this short survey here.

Speakers

Marcin OSUCHOWSKI. Ludwig Boltzmann Institute for Traumatology, The Research Center in Cooperation with AUVA; Deputy Editor-In-Chief of the ESICM ICMx Journal.

Denise BATTAGLINI. Consultant in intensive care at San Martino Policlinico Hospital, Genoa, Italy (IT). ESICM NEXT Committee Member.

Ahmed ZAHER. Oxford University Hospitals (UK). ESICM Next Committee member.

Episoder(91)

End of Life Care concepts in intensive care

End of Life Care concepts in intensive care

End-of-life care is an approach to a terminally ill patient that shifts the focus of care to symptom control, comfort, dignity, quality of life, and quality of dying rather than treatments aimed at cu...

3 Mai 202330min

Machine-learning-derived sepsis bundle of care

Machine-learning-derived sepsis bundle of care

The Surviving Sepsis Campaign (SSC) produces and regularly updates guidelines for managing patients with sepsis and septic shock. However, deviation from guidelines is frequently observed in the inten...

22 Mar 202326min

How to use biomarkers of infection or sepsis at the bedside

How to use biomarkers of infection or sepsis at the bedside

Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. In this context, biomarkers could be considered indicators of either infection or dysregulated host ...

15 Mar 202324min

MIPD of beta-lactam antibiotics and ciprofloxacin in critically ill patients

MIPD of beta-lactam antibiotics and ciprofloxacin in critically ill patients

Individualising drug dosing using model-informed precision dosing (MIPD) of beta-lactam antibiotics and ciprofloxacin has been proposed as an alternative to standard dosing to optimise antibiotic effi...

25 Jan 202317min

Management of severe bronchiolitis in infants <12 months old admitted to paediatric ICU

Management of severe bronchiolitis in infants <12 months old admitted to paediatric ICU

Bronchiolitis is a common lung infection in young children and infants. Approximately one-tenth of the affected children are admitted, and between 2 and 6% of them present a severe form and are referr...

18 Jan 202313min

Clustering analysis of geriatric and acute characteristics in very old patients on ICU admission

Clustering analysis of geriatric and acute characteristics in very old patients on ICU admission

The outcome of very old patients admitted to the intensive care unit (ICU) is determined by both the severity of the acute condition and the age-related decline of resilience to stress. However, that ...

11 Jan 202312min

My evidence-based nutrition protocol

My evidence-based nutrition protocol

Nutrition is an essential care we provide to critically ill patients aiming to avoid severe muscle wasting and weakness, which correlate with mortality and long-term burdens. Considering that the ICU ...

23 Nov 202222min

Management and outcomes of pregnant women with COVID-19

Management and outcomes of pregnant women with COVID-19

Pregnant women with COVID-19 are more likely to be admitted to the ICU and require invasive mechanical ventilation or venovenous extracorporeal membrane oxygenation (VV-ECMO). Nevertheless, only a few...

12 Okt 202212min

Populært innen Business og økonomi

stopp-verden
lydartikler-fra-aftenposten
dine-penger-pengeradet
rss-penger-polser-og-politikk
e24-podden
rss-borsmorgen-okonominyhetene
livet-pa-veien-med-jan-erik-larssen
finansredaksjonen
utbytte
pengepodden-2
pengesnakk
tid-er-penger-en-podcast-med-peter-warren
rss-sunn-okonomi
morgenkaffen-med-finansavisen
lederpodden
lederskap-nhhs-podkast-om-ledelse
rss-politisk-preik
rss-investering-gjort-enkelt
rss-markedspuls-2
rss-andelige-tanker-med-camillo