ESICM Talk27 Jun 2023

Results from the TAME trial

International guidelines recommend targeting normocapnia in adults with coma resuscitated after out-of-hospital cardiac arrest. However, normocapnia may be insufficient to restore and maintain adequate cerebral perfusion. Conversely, mild hypercapnia increases cerebral blood flow and may improve neurologic outcomes.

Nevertheless, the most effective Paco2 target in adults with coma resuscitated after out-of-hospital cardiac arrest has not been well studied in randomized trials.

Therefore, the Targeted Therapeutic Mild Hypercapnia After Resuscitated Cardiac Arrest (TAME) trial was conducted to test the hypothesis that targeted mild hypercapnia would improve neurologic outcomes at 6 months as compared with targeted normocapnia in adults with coma who had been resuscitated after out-of-hospital cardiac arrest.

Listen to the podcast for more insight into the hypothesis, methodology and findings from the TAME study.

Original paper: Mild Hypercapnia or Normocapnia after Out-of-Hospital Cardiac Arrest

Speakers

Claudio SANDRONI. Policlinico Universitario Agostino Gemelli, Rome (IT).

Markus SKRIFVARS. University of Helsinki (FI). Chair, ESICM Trauma & Emergency Medicine (TEM) Section.

Chiara ROBBA. University of Genova (IT). ESICM Neuro-Intensive Care (NIC) Section.

Denne episoden er hentet fra en åpen RSS-feed og er ikke publisert av Podme. Den kan derfor inneholde annonser.

Episoder(97)

Large language models in the ICU

Is artificial intelligence about to transform the ICU?In this new episode of the Future of Intensive Care podcast series, we dive into the rapidly evolving world of large language models and their gro...

20 Mai 8min

Advanced Practice in Nursing and Allied Health Professionals

What does advanced practice really look like in the ICU? In this podcast episode, we are joined by two advanced intensive care practitioners who share their roles, career journeys, and impact within t...

13 Mai 43min

Unmet Needs in PICS: Are We Measuring What Matters?

What truly matters in recovery after critical illness? In this episode, we explore the unmet needs in Post-Intensive Care Syndrome (PICS) and question whether current approaches are capturing the outc...

11 Mai 23min

Current state of AI in health and healthcare

Artificial Intelligence (AI) is transforming healthcare—but what does it really mean for the intensive Care Unit (ICU)? In this episode, we are honoured to welcome Prof. Derek Angus, who explores the ...

6 Mai 33min

Healthcare crisis: can innovation be the answer?

Can innovation really transform the future of intensive care?Join the first episode of the ESICM podcast series, The Future of Intensive Care. Prof. Maurizio Cecconi joins Dr Massimiliano Greco to exp...

22 Apr 18min

Redefining Precision Nutrition: Where Science Meets the patient’s bedside

In this episode of the educational podcast, we explore what precision nutrition truly means in intensive care. While the concept is widely discussed in research, many studies remain descriptive or rel...

8 Apr 31min

Why does renal recovery from AKI matter to us intensivists?

Acute Kidney Injury (AKI) is a frequent complication in critically ill patients and is associated with significant morbidity and mortality. However, the clinical relevance of AKI extends well beyond t...

18 Mar 24min