ARDS Phenotyping: from disease understanding to future bedside perspectives
To date, no specific pharmacotherapy has proven effective against acute respiratory distress syndrome ARDS. Results on the research domain have been ineffective in human trials, a gap attributed in pa...
19 Jun 202446min
Mechanical circulatory support for cardiogenic shock: a network meta-analysis of randomized controlled trials and propensity score-matched studies
Cardiogenic shock accounts for up to 5% of acute heart failure presentations and around 14–16% of patients reported in cardiac intensive care datasets. It complicates up to 15% of all myocardial infar...
12 Jun 202441min
Burned out in ICU professionals
Professional burnout has been described by WHO as a syndrome conceptualised as resulting from chronic workplace stress that has not been successfully managed. Intensive care unit (ICU) professionals a...
15 Mai 202413min
Inflammatory subphenotypes in patients at risk of ARDS: evidence from the LIPS-A trial
Acute respiratory distress syndrome (ARDS) remains a life-threatening syndrome, resulting in high morbidity and mortality. In ARDS patients and mechanically ventilated critically ill patients, two dis...
8 Mai 202421min
Brain ultrasound for the general intensivist
Cerebral ultrasound is a developing point-of-care tool for intensivists and emergency physicians, with an important role in diagnosing acute intracranial pathology. The use of transcranial Doppler has...
24 Apr 202416min
Phenotyping and endotyping patients to optimally set nutrition targets
Nutrition plays a vital role in the management of critically ill patients, and a tailored approach based on patient assessment, nutritional requirements, and clinical status is essential for optimisin...
10 Apr 202447min
Uncovering heterogeneity in sepsis: a comparative analysis of subphenotypes
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to an infection. Despite progress in the understanding of sepsis pathophysiology, no specific treatment has proven...
20 Mar 202419min
