How to use biomarkers of infection or sepsis at the bedside
Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. In this context, biomarkers could be considered indicators of either infection or dysregulated host ...
15 Mar 202324min
MIPD of beta-lactam antibiotics and ciprofloxacin in critically ill patients
Individualising drug dosing using model-informed precision dosing (MIPD) of beta-lactam antibiotics and ciprofloxacin has been proposed as an alternative to standard dosing to optimise antibiotic effi...
25 Jan 202317min
Management of severe bronchiolitis in infants <12 months old admitted to paediatric ICU
Bronchiolitis is a common lung infection in young children and infants. Approximately one-tenth of the affected children are admitted, and between 2 and 6% of them present a severe form and are referr...
18 Jan 202313min
Clustering analysis of geriatric and acute characteristics in very old patients on ICU admission
The outcome of very old patients admitted to the intensive care unit (ICU) is determined by both the severity of the acute condition and the age-related decline of resilience to stress. However, that ...
11 Jan 202312min
My evidence-based nutrition protocol
Nutrition is an essential care we provide to critically ill patients aiming to avoid severe muscle wasting and weakness, which correlate with mortality and long-term burdens. Considering that the ICU ...
23 Nov 202222min
Management and outcomes of pregnant women with COVID-19
Pregnant women with COVID-19 are more likely to be admitted to the ICU and require invasive mechanical ventilation or venovenous extracorporeal membrane oxygenation (VV-ECMO). Nevertheless, only a few...
12 Okt 202212min
Evolution of sedation management in the ICU
Intensive care unit (ICU) sedation practices have dramatically changed over the last 20 years. Nowadays, they include light levels of sedation, SAT, and the use of non-benzodiazepines. An overview of ...
14 Sep 202214min
When to initiate RRT?
Acute kidney injury is common in critically ill patients, and 10-15% of ICU patients receive renal replacement therapy (RRT). The timing of therapy initiation is limited by heterogeneity, but until 10...
7 Sep 202246min
