101 | David Baltimore on the Mysteries of Viruses

101 | David Baltimore on the Mysteries of Viruses

I recently saw an estimate that if you took all the novel coronaviruses in the world (the actual viruses, not patients), you could fit them into a bucket no more than a couple of liters in volume. A huge impact has been wrought by a very small amount of stuff. The world of viruses is vast and complicated, and we're still learning some of its basic features. Today's guest David Baltimore won the Nobel Prize in Physiology or Medicine for the discovery that genetic information in viruses could flow from RNA to DNA, establishing an exception to the Central Dogma of Biology. He is the author of the Baltimore Classification scheme for viruses, and has done important research in the role of viruses in diseases from AIDS to cancer. We talk about what viruses are, how they work, and the status of the novel coronavirus we are currently battling. David also has some strong opinions about public health and how we should be preparing for future outbreaks.

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David Baltimore received his Ph.D. in molecular biology from the Rockefeller Institute. He is currently the Robert Andrews Millikan Professor of Biology at Caltech. At age 37 he was awarded the Nobel Prize, which he shared with Howard Temin and Renato Dulbecco. He has served as the President of both Rockefeller University and Caltech, as well as President of the American Association for the Advancement of Science and the Founding Director of the Whitehead Institute for Biomedical Research. Among his other awards are the National Medal of Science and the Warren Alpert Foundation Prize.


Episoder(419)

73 | Grimes (c) on Music, Creativity, and Digital Personae

73 | Grimes (c) on Music, Creativity, and Digital Personae

Changing technologies have always affected how we produce and enjoy art, and music might be the most obvious example. Radio and recordings made it easy for professional music to be widely disseminated...

18 Nov 20191h 18min

72 | César Hidalgo on Information in Societies, Economies, and the Universe

72 | César Hidalgo on Information in Societies, Economies, and the Universe

Maxwell's Demon is a famous thought experiment in which a mischievous imp uses knowledge of the velocities of gas molecules in a box to decrease the entropy of the gas, which could then be used to do ...

11 Nov 20191h 16min

71 | Philip Goff on Consciousness Everywhere

71 | Philip Goff on Consciousness Everywhere

The human brain contains roughly 85 billion neurons, wired together in an extraordinarily complex network of interconnected parts. It's hardly surprising that we don't understand the mind and how it w...

4 Nov 20191h 34min

70 | Katie Mack on How the Universe Will End

70 | Katie Mack on How the Universe Will End

Cosmologists are always talking excitedly about the Big Bang and all the cool stuff that happened in the 14 billion years between then and now. But what about the future? We don't know for sure, but w...

28 Okt 20191h 23min

69 | Cory Doctorow on Technology, Monopoly, and the Future of the Internet

69 | Cory Doctorow on Technology, Monopoly, and the Future of the Internet

Like so many technological innovations, the internet is something that burst on the scene and pervaded human life well before we had time to sit down and think through how something like that should w...

21 Okt 20191h 17min

68 | Melanie Mitchell on Artificial Intelligence and the Challenge of Common Sense

68 | Melanie Mitchell on Artificial Intelligence and the Challenge of Common Sense

Artificial intelligence is better than humans at playing chess or go, but still has trouble holding a conversation or driving a car. A simple way to think about the discrepancy is through the lens of ...

14 Okt 20191h 22min

67 | Kate Jeffery on Entropy, Complexity, and Evolution

67 | Kate Jeffery on Entropy, Complexity, and Evolution

Our observable universe started out in a highly non-generic state, one of very low entropy, and disorderliness has been growing ever since. How, then, can we account for the appearance of complex syst...

7 Okt 20191h 12min

66 | Will Wilkinson on Partisan Polarization and the Urban/Rural Divide

66 | Will Wilkinson on Partisan Polarization and the Urban/Rural Divide

The idea of "red states" and "blue states" burst on the scene during the 2000 U.S. Presidential elections, and has a been a staple of political commentary ever since. But it's become increasingly clea...

30 Sep 20191h 52min

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