On Pharma Trends and Big Company Innovation

with Wei Luo, David Rumsey (@davidrumseymaps), and Hanne Tidnam (@omnivorousread) In this episode, Wei Luo, founding COO of DeepMap -- who build HD maps for autonomous vehicles -- and David Rumsey, fo...

16 Sep 201738min

with Juan Benet and Chris Dixon The story of how innovation happens is a long one — from government funding early basic research, to the heyday of corporate R&D like Bell Labs, to startups as experime...

15 Sep 201721min

with Michael Dearing (@mcgd), Bob Sutton (@work_matters), and Hanne Tidnam (@omnivorousread) Bob Sutton's book The No Asshole Rule was all about how to foster company cultures that don't tolerate assh...

13 Sep 201734min

with Russ Roberts, Noah Smith, and Sonal Chokshi Beyond the overly simplistic framing of trade as “good” or “bad” — by politicians, by Econ 101 — why is the topic of trade (or rather, economies and pe...

10 Sep 201738min

We tend to talk about tech and parenting through devices and artifacts -- screen time, to code or not to code -- but actually, there's a bigger, macro picture at play there: game theory, economic ince...

5 Sep 201729min

with Clayton Christensen, Marc Andreessen, and Steven Levy In business, mistakes of omission may be just as bad as (if not worse than) mistakes of commission -- simply because of the loss in potential...

2 Sep 201737min

"Young hungry and scrappy" is how Hamilton described his country, and it's how many -- including the guests on this episode -- describe startups... or more precisely, the mindset that engineers in sta...

30 Aug 201728min

What is "infrastructure" actually? In the 19th and 20th century, that usually meant the transportation systems supporting roadways, airports, trains... but we don't even really know yet what it might ...

25 Aug 201722min