The discovery that led to Covid vaccines

Dr Katalin Karikó grew up in a small town in Hungary with no electricity or running water at home. She overcame great adversity to become a scientist and publish a groundbreaking paper in 2005 showing how the mRNA molecule could be used to protect the human immune system from viruses. But, her findings were initially overlooked and she even lost her job after failing to attract funding. However, she persisted with her research, which laid the scientific groundwork for mRNA vaccines that saved countless lives during the Covid pandemic. She was awarded the Nobel Prize in Physiology or Medicine in 2023. She speaks to Ben Henderson.

Eye-witness accounts brought to life by archive. Witness History is for those fascinated by the past. We take you to the events that have shaped our world through the eyes of the people who were there. For nine minutes every day, we take you back in time and all over the world, to examine wars, coups, scientific discoveries, cultural moments and much more.

Recent episodes explore everything from football in Brazil, the history of the ‘Indian Titanic’ and the invention of air fryers, to Public Enemy’s Fight The Power, subway art and the political crisis in Georgia. We look at the lives of some of the most famous leaders, artists, scientists and personalities in history, including: visionary architect Antoni Gaudi and the design of the Sagrada Familia; Michael Jordan and his bespoke Nike trainers; Princess Diana at the Taj Mahal; and Görel Hanser, manager of legendary Swedish pop band Abba on the influence they’ve had on the music industry. You can learn all about fascinating and surprising stories, such as the time an Iraqi journalist hurled his shoes at the President of the United States in protest of America’s occupation of Iraq; the creation of the Hollywood commercial that changed advertising forever; and the ascent of the first Aboriginal MP.

(Photo: Dr Katalin Karikó. Credit: Janos Kummer/Getty Images)