Episode 376: 387. Methods Monday and an Example of Subgroup Analysis
https://www.nejm.org/doi/full/10.1056/NEJMoa2405923?query=clinical-medicine Mineralocorticoid receptor antagonists have been shown to reduce mortality in patients after myocardial infarction with cong...
17 Mar 20258min
Episode 375: 386. Could half dose anticoagulation be the answer?
Estimated 5-year incidence of recurrent VTE was similar in the reduced-dose and full-dose groups (2.2% and 1.8%). Estimated 5-year bleeding incidence was significantly lower with reduced-dose than wi...
14 Mar 20258min
Episode 374: 385. PRACTICE CHANGER! Male-Partner Treatment to Prevent Recurrence of Bacterial Vaginosis
https://www.nejm.org/doi/full/10.1056/NEJMoa2405404NNT of 4! systemic metronid and topical clinda bid for one week
12 Mar 20256min
Episode 373: 384. Chronic Kidney Disease and Empagliflozin Legacy Effect
What Was Studied?The EMPA-KIDNEY trial followed 6,609 CKD patients at risk of disease progression. Participants were randomly assigned to receive empagliflozin (10 mg daily) or a placebo for a median ...
11 Mar 20259min
Episode 372: 383. What is the GFR at which we stop metforin?
Metformin while not necessarily first line therapy for diabetes depending on the patients co-morbid conditions it is certainly highly ranked on the list of medications! I know often metformin is stopp...
6 Mar 202510min
Episode 371: 382. Is it safe to give the flu and covid vaccine at the same time?
https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2825813Conclusions and Relevance In this randomized clinical trial assessing simultaneous vs sequential administration of mRNA COVID-19 an...
4 Mar 20257min
Episode 370: 381. Relative efficacy of prehabilitation interventions and their components
https://www.bmj.com/content/388/bmj-2024-081164systematic review and meta-analysis on prehabilitation before surgery, published in the BMJ in February 2025.Prehabilitation aims to prepare patients for...
27 Feb 20257min
Episode 369: 380. REPOST mammo part 2
Mammograms
24 Feb 202520min
