Episode 171: 171.  Diabetes Drugs, Statins and Muscle Pain, Vitamin D and COVID, Acne and Food

Episode 171: 171. Diabetes Drugs, Statins and Muscle Pain, Vitamin D and COVID, Acne and Food

SGLT2 inhibitors and GLP1 agonists administered without metformin compared to other glucose‐lowering drugs in patients with type 2 diabetes mellitus to prevent cardiovascular events: A systematic review - Escobar - 2021 - Diabetic Medicine - Wiley Online Library

Yes these fancy new drugs work with and without metformin but that does not mean these drugs should be first line!!


Effect of a Single High Dose of Vitamin D3 on Hospital Length of Stay in Patients With Moderate to Severe COVID-19: A Randomized Clinical Trial | Complementary and Alternative Medicine | JAMA | JAMA Network


Yep even 200,000IU of vit D does nothing except raise your vit d level.

Diet and acne: review of the evidence from 2009 to 2020 - Dall’Oglio - - International Journal of Dermatology - Wiley Online Library


What you eat does mess with your acne, or at least says this large observational trial.


Statin treatment and muscle symptoms: series of randomised, placebo controlled n-of-1 trials | The BMJ

The muscle aches with statins is a common event that it occurs as frequently with the active drug as it does with placebo

Episoder(385)

Episode 222: 222. Ablation for AFIB in patients with HFrEF

Episode 222: 222. Ablation for AFIB in patients with HFrEF

Consider ablation in patients who have an EF < 35% and atrial fibrillation the NNT for all cause mortality was 7 at 18 months https://www.nejm.org/doi/full/10.1056/NEJMoa2306037

19 Jan 20244min

Episode 221: 221. Nurse Led Sleep Restriction IMPROVES Insomnia

Episode 221: 221. Nurse Led Sleep Restriction IMPROVES Insomnia

Sleep restriction therapy led by nurses with only 4 hours of education significantly improved patients insomnia at 6 months. More info HERE ___>https://thrive.kaiserpermanente.org/care-near-you/northe...

18 Jan 20246min

Episode 220: 220. Semaglutide at 1yr Gives Small Improvement in Questionnaire for those with HFpEF

Episode 220: 220. Semaglutide at 1yr Gives Small Improvement in Questionnaire for those with HFpEF

Kansas City Cardiomyopathy Questionnaire clinical summary score was improved by 7.8 in those individuals with HFpEF that took semaglutide for one year compared to those that took placebo. This is a sm...

17 Jan 20245min

Episode 219: 219. Oral Iron better with vitamin C  on an empty stomach

Episode 219: 219. Oral Iron better with vitamin C on an empty stomach

When taking Ferrous Fumarate a little bit of vitamin C or an 8 ounce glass of orange juice with an otherwise empty stomach will improve the absorption- this absorption is decreased with food and coffe...

16 Jan 20245min

Episode 218: 218. Semaglutide and CAD But No Diabetes - Decrease Event$$$$$$

Episode 218: 218. Semaglutide and CAD But No Diabetes - Decrease Event$$$$$$

https://www.nejm.org/doi/full/10.1056/NEJMoa2307563Semaglutide and CAD but no diabetes decreases events NNT of 66 at 40 months but a predicted price tag of 3.5 million dollars.

12 Jan 20247min

Episode 217: 217. Olanzapine 2.5mg for weight gain with advance cancer

Episode 217: 217. Olanzapine 2.5mg for weight gain with advance cancer

Olanzapine 2.5mg for weight gain with advance cancer NNT of 50 for >5% weight gainhttps://pubmed.ncbi.nlm.nih.gov/36977285/

11 Jan 20245min

Episode 216: 216. AFIB- RATE or ABLATE-- New guidelines

Episode 216: 216. AFIB- RATE or ABLATE-- New guidelines

ACC/AHA just came out with new guidelines on AFIB if you need some light reading material! (big take home rhythm not rate, and not equal, read below for more information) A HUGE piece of new is that n...

27 Des 20239min

Episode 215: 215. Enteric coated or uncoated aspirin, which is better or safer?

Episode 215: 215. Enteric coated or uncoated aspirin, which is better or safer?

Effectiveness and Safety of Enteric-Coated vs Uncoated Aspirin in Patients With Cardiovascular Disease: A Secondary Analysis of the ADAPTABLE Randomized Clinical Trial | Clinical Pharmacy and Pharmaco...

20 Des 20234min

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