Episode 171: 171.  Diabetes Drugs, Statins and Muscle Pain, Vitamin D and COVID, Acne and Food

Episode 171: 171. Diabetes Drugs, Statins and Muscle Pain, Vitamin D and COVID, Acne and Food

SGLT2 inhibitors and GLP1 agonists administered without metformin compared to other glucose‐lowering drugs in patients with type 2 diabetes mellitus to prevent cardiovascular events: A systematic review - Escobar - 2021 - Diabetic Medicine - Wiley Online Library

Yes these fancy new drugs work with and without metformin but that does not mean these drugs should be first line!!


Effect of a Single High Dose of Vitamin D3 on Hospital Length of Stay in Patients With Moderate to Severe COVID-19: A Randomized Clinical Trial | Complementary and Alternative Medicine | JAMA | JAMA Network


Yep even 200,000IU of vit D does nothing except raise your vit d level.

Diet and acne: review of the evidence from 2009 to 2020 - Dall’Oglio - - International Journal of Dermatology - Wiley Online Library


What you eat does mess with your acne, or at least says this large observational trial.


Statin treatment and muscle symptoms: series of randomised, placebo controlled n-of-1 trials | The BMJ

The muscle aches with statins is a common event that it occurs as frequently with the active drug as it does with placebo

Episoder(385)

15. Clinical Testing

15. Clinical Testing

An overview of a few studies and information regarding inpatient and outpatient testing. "The first principle of solid wisdom is discretion.." --Norman MacDonald. A little discussion on understanding ...

21 Okt 201432min

14. IV Fluids part 2

14. IV Fluids part 2

Bottoms up on the last discussion on fluids and a review of a few of the trials that contribute to the current mindset in EBM. Andrew creates his own "Mike Tyson Theory of fluids" and Joe subscribes t...

3 Okt 201424min

13. IV Fluids part 1

13. IV Fluids part 1

A quick discussion one the topic of which patient to give which fluid. Review of studies from the 90s to 2014 with demographics including pre/post Operative, Septic patient and even Rattus Rattus. (th...

25 Sep 201423min

12. Dexa Scan Part 2

12. Dexa Scan Part 2

Hard topic and difficult discussion continues about reasonable intervention and evaluation of therapy for osteoporosis. Andrew starts right off with his personal recommendation on the screening of low...

10 Sep 20147min

11. The Dexa Scam

11. The Dexa Scam

Hard hitting discussion on the evidence on soft bones and the best screening and treatment options. This episode was broken into two parts because Joe needed to run a full NIH Stroke Scale on Andrew m...

1 Sep 201429min

10. Vitamin D Part 2

10. Vitamin D Part 2

Who and when to test. Dose and frequency along with route of administration of Vitamin D are discussed along with 12 studies of outcomes and complications/benefits of each. Joe discovers Andrew is bel...

13 Aug 201431min

8. Watch Were You Are Putting Your Hands...

8. Watch Were You Are Putting Your Hands...

You might be outside the guidelines soon. Joe and Andrew discuss the newest recommendations from ACP regarding bimanual/pelvic exams. Andrew can't hold it any longer and breaks into song for the first...

6 Jul 201434min

7. Diabetes. It's Not Over Until the Intervals Are Over.

7. Diabetes. It's Not Over Until the Intervals Are Over.

Don't celebrate just yet, the confidence intervals aren't all the way over the line. Andrew gives yet another history lesson on the improvements in Diabetes and runs over some of the recent talk abou...

23 Jun 201430min

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