Episode 270: 269. What is the Harm in Aspirin?

Episode 270: 269. What is the Harm in Aspirin?

The trial was terminated after 1015 patients with atrial cardiopathy had been randomized to receive either apixaban or aspirin for a mean follow-up of 1.8 years, recurrent stroke rates were identical (40 events per group; 4.4% annualized rate). There were 7 symptomatic intracranial hemorrhages in the aspirin group and none in the apixaban group, though other major hemorrhages occurred at similar rates

Aspirin is not benign and has real risk--

BTW don't give anticoagulation if the patient does not have atrial fib.

https://jamanetwork.com/journals/jama/article-abstract/2814933

Episoder(385)

Episode 326: 325. The Mysterious NNT

Episode 326: 325. The Mysterious NNT

What is a quick and easy way to calculate the NNT

30 Jul 20247min

Episode 325: 324. METHODS MONDAY

Episode 325: 324. METHODS MONDAY

What is the different between Absolute and Relative risk reduction

29 Jul 20248min

Episode 324: 323. Is Calcium Bad For You? Calcium Supplementation? Eating Calcium?

Episode 324: 323. Is Calcium Bad For You? Calcium Supplementation? Eating Calcium?

https://heart.bmj.com/content/108/12/964https://www.ahajournals.org/doi/10.1161/JAHA.116.003815We have a study that says leads to increase all cause death with calcium supplementsWe have a study that ...

26 Jul 202413min

Episode 323: 322. Follow-up to Adolescence after Early Peanut Introduction for Allergy Prevention

Episode 323: 322. Follow-up to Adolescence after Early Peanut Introduction for Allergy Prevention

https://evidence.nejm.org/doi/full/10.1056/EVIDoa2300311Peanut consumption, starting in infancy and continuing to age 5 years, provided lasting tolerance to peanut into adolescence irrespective of sub...

24 Jul 20245min

Episode 322: 321. Long-Term Outcomes in Patients with Low Risk Prostate Cancer

Episode 322: 321. Long-Term Outcomes in Patients with Low Risk Prostate Cancer

https://jamanetwork.com/journals/jama/article-abstract/2819352Conclusions and Relevance  In this study, 10 years after diagnosis, 49% of men remained free of progression or treatment, less than 2% dev...

23 Jul 20246min

Episode 321: 320. What is the Association of Blood Lipids, Lipoproteins, and Apolipoproteins With Risk of Coronary Heart Disease

Episode 321: 320. What is the Association of Blood Lipids, Lipoproteins, and Apolipoproteins With Risk of Coronary Heart Disease

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11179824/This study did something smart in that they broke it down by white black Chinese and then also had 36 lab test they were looking at and they then ...

19 Jul 20248min

Episode 320: 319. President Biden has COVID, Should the First Lady Take Paxlovid?

Episode 320: 319. President Biden has COVID, Should the First Lady Take Paxlovid?

https://www.nejm.org/doi/full/10.1056/NEJMoa2309002In this placebo-controlled trial, postexposure prophylaxis with nirmatrelvir–ritonavir for 5 or 10 days did not significantly reduce the risk of symp...

18 Jul 20248min

Episode 319: 318. Risk of Nonarteritic Anterior Ischemic Optic Neuropathy in Patients Prescribed Semaglutide

Episode 319: 318. Risk of Nonarteritic Anterior Ischemic Optic Neuropathy in Patients Prescribed Semaglutide

Risk of Nonarteritic Anterior Ischemic Optic Neuropathy in Patients Prescribed Semaglutidethis paper out in JAMA makes you think this is an issue but likely just too much noise with only 17 patietns a...

17 Jul 20249min

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