Episode 289: 288. An RCT for Time Restricted Eating!

Episode 289: 288. An RCT for Time Restricted Eating!

41 adults (mean age, 59) with obesity (mean weight, 99 kg) and prediabetes or diet-controlled diabetes – everyone got the same diet. Same micro- and macronutrient composition; same calorie amounts

Food was prepared in a study kitchen and consumed onsite or taken home.

Key difference

The intervention group was instructed to eat between 8 a.m. and 6 p.m. and to consume 80% of calories by 1 p.m. The control group was instructed to eat between 8 a.m. and midnight, with 55% of calories after 5 p.m.


Weight loss in the two groups was similar at 12 weeks (about 2.4 kg).

3 months—and no difference—


https://www.acpjournals.org/doi/10.7326/M23-3132

Episoder(387)

Episode 296: 295. What is the Best Blood Pressure In the Nursing Home?

Episode 296: 295. What is the Best Blood Pressure In the Nursing Home?

In a retrospective cohort study of Veterans Affairs (VA) nursing home residents during 2006 to 2019, researchers identified 13,000 residents who initiated a first or additional antihypertensive medica...

29 Mai 20247min

Episode 295: 294. SGLT2 Inhibitors and Stage 5 CKD

Episode 295: 294. SGLT2 Inhibitors and Stage 5 CKD

SGLT-2 inhibitors have not been evaluated in patients with stage 5 CKD (CKD 5; eGFR, ≤15 mL/minute/1.73 m2). Investigators in Taiwan retrospectively assessed 5 years of outcome data for nearly 48,000 ...

28 Mai 20245min

Episode 294: 293. Should GLP-1 Agonist be Held Prior to Procedure or Surgery?

Episode 294: 293. Should GLP-1 Agonist be Held Prior to Procedure or Surgery?

glucagon-like peptide-1 (GLP-1) receptor agonists can delay gastric emptying, the American Society of Anesthesiologists (ASA) say For patients on daily dosing consider holding GLP-1 agonists on the da...

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Episode 293: 292. An Antibiotic RCT for Community Acquired Pneumonia

Episode 293: 292. An Antibiotic RCT for Community Acquired Pneumonia

But now we have RCT data—278 adults with moderate CAP who were hospitalized (but not in intensive care) to receive either a β-lactam antimicrobial plus clarithromycin or a β-lactam alone. (all patient...

23 Mai 20244min

Episode 292: 291. Does CHATGPT Have a Career In Pathology?

Episode 292: 291. Does CHATGPT Have a Career In Pathology?

AI technology was highly accurate at identifying malignancies and tumor origins — as accurate as senior pathologists, and significantly more accurate than junior pathologists.   Patients with cancer o...

22 Mai 20245min

Episode 291: 290. When Should You Use IV Albumin?

Episode 291: 290. When Should You Use IV Albumin?

HERE IS WHEN IT IS RECOMMENDED TO USE ALBUMIN In patients with cirrhosis and spontaneous bacterial peritonitis, to substantially limit kidney impairment and mortality (low-certainty evidence) THIS IS ...

21 Mai 20246min

Episode 290: 289. Which GLP-1 is the Best Weight Loss Drug?

Episode 290: 289. Which GLP-1 is the Best Weight Loss Drug?

The results for weight loss was  Tirzepatide also known as mounjaro – 8.5 kg  Semaglutide also known as Ozempic -3.1 kg lost Liraglutide aka Victoza – 1.3 kg lostTirzepatide also known as mounjaro – 8...

20 Mai 20245min

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