Are GLP-1 Drugs "the Greatest Medical Breakthrough of the 21st Century"?

Are GLP-1 Drugs "the Greatest Medical Breakthrough of the 21st Century"?

In the past few years, we've learned that GLP-1 drugs don’t just help with diabetes or increase people’s feelings of fullness to help them lose weight. They have broad effects on substance abuse and behavior. They even seem to help with otherwise incurable illnesses, like Alzheimer's and schizophrenia. This month, a team of scientists studying 2 million patients in the Veterans Affairs medical system found that GLP-1s were associated with “a reduced risk of substance use and psychotic disorders, seizures, neurocognitive disorders (including Alzheimer’s disease and dementia), coagulation disorders (clotting), cardiometabolic disorders (like strokes and heart attacks), infectious illnesses and several respiratory conditions.” Today’s guest is a coauthor on the paper, Ziyad Al-Aly. He is a physician-scientist at Washington University in St. Louis. We talk about his new paper, the steps he took to make sure his findings were trustworthy, why GLP-1 drugs might work so well, what they’re teaching us about the brain and body, how they’re scrambling our sense of where volition begins and where free will ends, and what scientists should do next with the revelation that these drugs have effects that go far beyond obesity and diabetes. If you have questions, observations, or ideas for future episodes, email us at PlainEnglish@Spotify.com. Host: Derek Thompson Guest: Ziyad Al-Aly Producer: Devon Baroldi Links: Al-Aly et al. on the effectiveness and risks of GLP-1 drugs [link] Learn more about your ad choices. Visit podcastchoices.com/adchoices

Episoder(348)

America's Biggest Car Companies Are in Trouble

America's Biggest Car Companies Are in Trouble

Today, the media vibes around electric vehicles are all bad. But if you lift up and take in the big picture, electric vehicles and hybrids are taking over the market. Gas-powered cars are as much in s...

26 Mar 202450min

Should the U.S. Ban TikTok?

Should the U.S. Ban TikTok?

Derek shares his thoughts on the question of the moment in tech and tech politics. If you have questions, observations, or ideas for future episodes, email us at PlainEnglish@Spotify.com.  Host: Derek...

19 Mar 202433min

How Hollywood’s Hit Formula Flopped—and What Could Come Next

How Hollywood’s Hit Formula Flopped—and What Could Come Next

Today, we’re talking about movies, the philosophy of hits in Hollywood, and why we might be at a fascinating inflection point in how the entertainment industry thinks about popularity and prestige. We...

12 Mar 202451min

What Many Economists (and I) Got Wrong About This Economy

What Many Economists (and I) Got Wrong About This Economy

One of my New Year’s resolutions for 2024 was to do more episodes with people who think I'm wrong about something. For example, I've done several episodes about how the U.S. economy is doing much bett...

5 Mar 202429min

Why the "Need for Chaos" Is Eating American Politics

Why the "Need for Chaos" Is Eating American Politics

Today’s episode is about one of the most interesting pieces of research I’ve read in the past year. It's an idea called "need for chaos," and the truth is that I literally cannot stop thinking about i...

1 Mar 202435min

Why Americans Stopped Hanging Out—and Why It Matters

Why Americans Stopped Hanging Out—and Why It Matters

Today’s episode is about the extraordinary decline in face-to-face socializing in America—and the real stakes of the country’s hanging-out crisis. From 2003 to 2022, American adults reduced their aver...

27 Feb 20241h 10min

"We’re Seeing a Fundamental Reorganization of Work in America"

"We’re Seeing a Fundamental Reorganization of Work in America"

Today’s episode is about arguably the most important economic statistic out there: real (or inflation-adjusted) wage growth. For much of the last few years, many people's real wages have declined. But...

23 Feb 202438min

How to Have the Hardest Conversations—in Marriage, Politics, and Life

How to Have the Hardest Conversations—in Marriage, Politics, and Life

Life is a series of conversations. Our relationships, friendships, marriages, breakups, makeups, hirings, promotions, and firings are mostly the story of two people talking. And many of these conversa...

20 Feb 202440min

Populært innen Politikk og nyheter

giver-og-gjengen-vg
aftenpodden-usa
aftenpodden
stopp-verden
forklart
i-retten
popradet
det-store-bildet
fotballpodden-2
nokon-ma-ga
dine-penger-pengeradet
rss-gukild-johaug
bt-dokumentar-2
aftenbla-bla
hanna-de-heldige
rss-ness
frokostshowet-pa-p5
rss-penger-polser-og-politikk
rss-dannet-uten-piano
e24-podden