#101 - What is Type 2 Inflammation?

#101 - What is Type 2 Inflammation?

What do asthma, eczema, EoE, and nasal polyps have in common? They all stem from Type 2 inflammation!

Type 2 inflammation is a major cause of many allergic and inflammatory conditions, yet it remains widely misunderstood. In this first episode of our four-part series on Type 2 Inflammation, we discuss the basics, unpack its impact on the immune system, explain how it contributes to chronic inflammation in the body, and explain why it matters for treatment and management.

What we cover in our episode about Type 2 Inflammation
  • Understanding Inflammation: Inflammation is your body’s natural defence mechanism, but it can become problematic when it turns chronic.
  • Normal vs. Chronic Inflammation: Not all inflammation is bad! Learn the difference between the body’s normal immune response and long-term chronic inflammation.
  • What Sets Type 2 Inflammation Apart? Unlike other immune responses, Type 2 inflammation involves a specific pathway.
  • Key Players in Type 2 Inflammation: Th2 cells, cytokines (IL-4, IL-5, IL-13), IgE antibodies, and eosinophils.
  • Measuring Type 2 Inflammation: How blood tests can help determine if Type 2 inflammation is contributing to your symptoms.

Want to know more? Type 2 Inflammation Overview – Explains the role of Type 2 inflammation in conditions like asthma and nasal polyps.

This podcast is for informational purposes only and does not substitute for professional medical advice. If you have any medical concerns, always consult with your healthcare provider.

Produced in partnership with The Allergy & Asthma Network. Thanks to Sanofi and Regeneron for sponsoring today’s episode. While they support the show, all opinions are our own, and sponsorship doesn’t influence our content or editorial decisions. Any mention of brands is for informational purposes and not an endorsement.

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Episoder(172)

#170 - When Asthma Peak Week Hits Adults

#170 - When Asthma Peak Week Hits Adults

Most asthma peak week coverage focuses on kids heading back to school. But adults with asthma are just as much at risk, and often don't realize it until they're already in trouble.  Kortney and Dr. Pa...

13 Aug 29min

#169 - What a School Nurse Wants Parents to Know About Asthma Peak Week

#169 - What a School Nurse Wants Parents to Know About Asthma Peak Week

Every September, doctors see a jump in asthma attacks and ER visits. It's called Asthma Peak Week, and it usually hits the third week of September, right when families are settling into their school r...

6 Aug 41min

#168 - Wildfire Smoke and Your Lungs, What You Need to Know

#168 - Wildfire Smoke and Your Lungs, What You Need to Know

Wildfire smoke used to feel like someone else's problem. Now it can show up on air quality alerts hundreds of miles from any actual fire, and for anyone with asthma, that hazy sky can mean real troubl...

30 Jul 23min

#167 - How Is Chronic Rhinosinusitis Without Nasal Polyps Diagnosed and Treated?

#167 - How Is Chronic Rhinosinusitis Without Nasal Polyps Diagnosed and Treated?

Chronic rhinosinusitis without nasal polyps (CRSsNP) is the type that makes up most chronic sinusitis cases. It's often mistaken for allergies, a lingering cold, or migraines, which can delay a proper...

24 Jul 28min

#166 - How Pregnancy and Your Baby's Gut Microbiome Play a Role in Food Allergy Prevention

#166 - How Pregnancy and Your Baby's Gut Microbiome Play a Role in Food Allergy Prevention

Food allergy prevention is something most families think about once a baby starts eating. But the gut microbiome begins developing before birth, and what happens during pregnancy matters for the devel...

16 Jul 21min

#165: Gut Microbiome's Role in Food Allergies

#165: Gut Microbiome's Role in Food Allergies

You have probably heard the word "microbiome", but what does it actually mean for someone living with a food allergy? Dr. Carina Venter, a registered dietitian, joins us to break down the gut’s role i...

9 Jul 35min

#164 - New Chronic Hives Guidelines: A Look at What's Changing

#164 - New Chronic Hives Guidelines: A Look at What's Changing

In this journal club episode, we break down the draft of the Chronic Urticaria Guidelines: 2026 AAAAI/ACAAI Joint Task Force (JTF) on Practice Parameters GRADE- and Institute of Medicine-based recomme...

2 Jul 32min

#163 - Understanding Chronic Spontaneous Urticaria: Hives Demystified

#163 - Understanding Chronic Spontaneous Urticaria: Hives Demystified

Join Kortney and Dr. Payel Gupta as they unpack chronic spontaneous urticaria. Together, they define what hives actually are, explain how CSU is different from an allergic reaction and other types of ...

26 Jun 22min

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