Sam Apple | The Connection Between Glucose, Insulin & Cancer KKP: 344

Sam Apple | The Connection Between Glucose, Insulin & Cancer KKP: 344

Today, I am blessed to have here with me Sam Apple. He is on the faculty of the MA in Science Writing and MA in Writing programs at Johns Hopkins. Prior to his arrival at Johns Hopkins, Apple taught creative writing and journalism at the University of Pennsylvania for ten years. He holds a BA in English and Creative Writing from the University of Michigan and an MFA in Creative Nonfiction from Columbia University. Apple is the author of Ravenous American Parent, and Schlepping Through the Alps. He has published short stories, personal essays, satires, and journalistic features on a wide range of topics. In recent years, he has primarily written about science and health. His work has appeared in The New York Times Magazine, The New Yorker, The Atlantic, Wired, The Los Angeles Times, The Financial Times Magazine, ESPN The Magazine, The MIT Technology Review, and McSweeney’s, among many other publications. Schlepping Through the Alps was a finalist for the PEN America Award for a first work of nonfiction. In this episode, Sam talks about the inspiration behind his book Ravenous: Otto Warburg, the Nazis, and the Search for the Cancer-Diet. We dive into Otto Warburg’s work and how the Nazis protected him for his cancer science. Sam explains how sugar can promote cancer growth and what steps you can take to lower your insulin levels. Tune in as we chat about fasting, therapies for cancer, and the importance of exercise. Get Sam’s book here: https://www.amazon.com/Ravenous-Warburg-Search-Cancer-Diet-Connection/dp/1631493159/benazadi-20 Order Keto Flex: http://www.ketoflexbook.com -------------------------------------------------------- / / E P I S O D E S P ON S O R S PureForm Omega Plant Based Oils (Best Alternative to Fish Oil): http://www.purelifescience.com Use ben4 for $4.00 off. Upgraded Formulas Hair Mineral Deficiency Analysis & Supplements: http://www.upgradedformulas.com Use BEN10 at checkout for 10% off your order. Paleo Valley beef sticks, apple cider vinegar complex, organ meat complex & more. Use the coupon code KETOKAMP15 over at https://paleovalley.com/ to receive 15% off your entire order. Text me the words "Podcast" +1 (786) 364-5002 to be added to my contacts list. [00:30] The Inspiration Behind Ravenous: Otto Warburg, the Nazis, and the Search for the Cancer-Diet Read Ravenous: Otto Warburg, the Nazis, and the Search for the Cancer-Diet Connection: https://www.amazon.com/Ravenous-Warburg-Search-Cancer-Diet-Connection/dp/1631493159/benazadi-20 Sam was interested in researching metabolic disease and metabolic health. Plus, Gary Taubes inspired him. Sam was really surprised to learn that that cancer was associated with diabetes, insulin resistance, obesity, and cardiovascular disease. He wanted to dig further on the connection between cancer and metabolic disease. [02:10] The Nazis Protected Warburg For His Cancer Research In 1923, Warburg makes this famous discovery called the Warburg Effect. Cancer cells take up a lot more glucose than other cells and burn it without oxygen; they ferment it, just like microorganisms do. Warburg also has made other discoveries about how cells breathe and use oxygen. He wins the Nobel Prize in 1931. In 1933, the Nazis come along. Despite having a Jewish father and being openly gay, the Nazis protected Warburg because they were interested in his cancer research. [06:50] Warburg’s Studies Started To Disappear After The War After the war, Warburg’s cancer research really starts to disappear. Australia in the 1950s famously discovered the structure of DNA. Eventually, we had a new sort of genetic understanding of cancer where we can now identify specific mutations. So, how cells take up glucose and shift their metabolism was considered irrelevant because of the study of genetics. Warburg’s studies take peoeple back to diet, and there’s a huge bias against taking diet seriously. [12:20] What Sugar Does To Promote Cancer Growth If cancer is about these metabolic shifts inside of a cell, what is it about the way we eat that affects the way a cell eats? In America, one out of three women are diagnosed with cancer within their lifetime. For men, it's about one in two. Cancer is closely linked to obesity. 13 of the deadliest cancers have been solidly linked to obesity. Sam wanted to know if obesity was causing cancer or if something was driving both. Elevated levels of the hormone insulin are responsible for obesity and give microscopic cancers a chance to grow and thrive. What is it about our diet that causes insulin to rise? Sugar! The increase in sugar consumption maps pretty closely to the rise of diabetes, heart disease, and cancer. [19:30] How A Keto Diet That Will Help You Prevent Cancer Sam is a huge believer that keto is a logical way to prevent cancer. The single most important thing you can do to improve your odds for cancer prevention is to keep your insulin levels low. Hyperinsulinemia promotes the growth of cancer. So, it’s important to follow a diet that keeps your insulin levels down. [22:20] Intermittent Fasting Is Another Great Way To Lower Insulin Intermittent fasting is one very successful strategy for keeping insulin down. If you can fast consistently, it seems to work quite effectively on lowering insulin. Fasting can lead to weight loss because it lowers insulin levels in the body. Sam wants to point out that thin people can still have insulin resistance. In some ways, being naturally thin can actually be a disadvantage because you can't store subcutaneous fat. [26:30] How To Optimize Insulin and Glucose Levels To Be Proactive Instead of Reactive You can't outrun a bad diet. However, exercise can help you feel better and make you more inspired to follow a low-carb diet. After workouts, you can be inspired to eat healthily and continue to feel good. Once you understand that sugar is linked to cancer, it should help you ditch it during mealtime. [38:30] Finding Therapies To Target Specific Cancer Mutations When cancer can eat lots of glucose, it's no longer thinking about dying; it's thinking about doing a lot more things. Based on which particular mutation you have, the oncologist will devise a treatment. Unfortunately, targeted therapies to specific mutations haven't been as successful as we would have liked. However, there are some cases where therapies will successfully target mutations. [42:25] The Best Preventative Measures To Preventing Cancer In The Future Eliminate sugar from your diet. Definitely eliminate liquid sugar from your diet. If you are insulin resistant, you need to reduce those insulin levels. Stop smoking. Cut out refined carbohydrates. AND MUCH MORE! Resources from this episode: Check out Sam’s Website: http://samapple.com/ Read Ravenous: Otto Warburg, the Nazis, and the Search for the Cancer-Diet Connection: https://www.amazon.com/Ravenous-Warburg-Search-Cancer-Diet-Connection/dp/1631493159/benazadi-20 Follow Sam Apple Twitter: https://twitter.com/sam_apple1 Instagram: https://www.instagram.com/samapplebooks/ Join theKeto Kamp Academy: https://ketokampacademy.com/7-day-trial-a WatchKeto Kamp on YouTube: https://www.youtube.com/channel/UCUh_MOM621MvpW_HLtfkLyQ Order Keto Flex: http://www.ketoflexbook.com -------------------------------------------------------- / / E P I S O D E S P ON S O R S PureForm Omega Plant Based Oils (Best Alternative to Fish Oil): http://www.purelifescience.com Use ben4 for $4.00 off. Upgraded Formulas Hair Mineral Deficiency Analysis & Supplements: http://www.upgradedformulas.com Use BEN10 at checkout for 10% off your order. Paleo Valley beef sticks, apple cider vinegar complex, organ meat complex & more. Use the coupon code KETOKAMP15 over at https://paleovalley.com/ to receive 15% off your entire order. Text me the words "Podcast" +1 (786) 364-5002 to be added to my contacts list. *Some Links Are Affiliates* // F O L L O W ▸ instagram | @thebenazadi | http://bit.ly/2B1NXKW ▸ facebook | /thebenazadi | http://bit.ly/2BVvvW6 ▸ twitter | @thebenazadi http://bit.ly/2USE0so ▸clubhouse | @thebenazadi Disclaimer: This podcast is for information purposes only. Statements and views expressed on this podcast are not medical advice. This podcast including Ben Azadi disclaim responsibility from any possible adverse effects from the use of information contained herein. Opinions of guests are their own, and this podcast does not accept responsibility of statements made by guests. This podcast does not make any representations or warranties about guests qualifications or credibility. Individuals on this podcast may have a direct or non-direct interest in products or services referred to herein. If you think you have a medical problem, consult a licensed physician.

Episoder(1127)

#1116 The 9 Everyday Foods Linked to Cancer, Obesity, and Inflammation That RFK Jr. Wants Banned — And What to Eat Instead With Ben Azadi

#1116 The 9 Everyday Foods Linked to Cancer, Obesity, and Inflammation That RFK Jr. Wants Banned — And What to Eat Instead With Ben Azadi

In this episode of the Metabolic Freedom Podcast, Ben Azadi uncovers the 9 common foods RFK Jr. wants banned—and why they may be fueling cancer, obesity, and chronic disease in America. From low-fat dairy and farmed salmon to microwave popcorn and deli meats, these everyday items are filled with hidden toxins, gut disruptors, and chemicals already banned in other countries. Ben explains what makes these foods dangerous, what safer swaps to choose, and why fixing our food system is the key to Making America Healthy Again. 🔥Free Masterclass with Ben Azadi Want to know exactly what to eat to lower inflammation, melt fat, and reclaim your health? 👉 Reserve your free spot at https://bit.ly/4nYBZaX  🔎 Find all of the Metabolic Freedom Sponsorship deals and coupon codes here: https://www.ketokamp.com/sponsorship-deals

4 Okt 16min

#1115 7 Strange Signs Your Fasting Is Actually Working (Even When It Feels Like It’s Not) With Ben Azadi

#1115 7 Strange Signs Your Fasting Is Actually Working (Even When It Feels Like It’s Not) With Ben Azadi

Fasting can feel uncomfortable—but those strange symptoms you experience are often signs that it’s actually working. In this episode, Ben Azadi shares 7 unusual signals that your body is shifting into fat-burning mode and deep repair, even when it doesn’t feel that way. You’ll learn: Why weight gain, bloating, or skin breakouts may signal detox and healing How brain fog, fatigue, or feeling cold show your mitochondria and hormones are adapting The emotional side of fasting—why irritability or mood swings are part of the process The truth about metallic breath and ketones as proof of fat burning Simple hacks to speed up autophagy and reduce symptoms 💡 Plus: how to break your fast the right way, support detox pathways, and know if you’re truly burning fat. 👉Reserve your free spot in my upcoming Fat Loss Masterclass:  https://bit.ly/3WjvBiE  👉Get your Keto-Mojo ketone + glucose meter here: http://ketokampmachine.com  🔎 Find all of the Metabolic Freedom Sponsorship deals and coupon codes here: https://www.ketokamp.com/sponsorship-deals

2 Okt 18min

#1114 Why America Got Fat on Lies While Japan Stayed Lean and Healthy — The 7 Root Causes You Need to Know With Ben Azadi

#1114 Why America Got Fat on Lies While Japan Stayed Lean and Healthy — The 7 Root Causes You Need to Know With Ben Azadi

In this episode of the Metabolic Freedom Podcast, Ben Azadi reveals the truth behind America’s obesity epidemic and why Japan has managed to stay lean. With obesity rates in the U.S. climbing toward 50%, while Japan’s remain under 5%, the difference isn’t willpower — it’s culture, food quality, and a system designed for profit. Ben uncovers the seven root causes keeping Americans sick — from sugar addiction and portion distortion to toxic seed oils, junk-filled school lunches, and fake convenience foods. You’ll also learn how Japan’s food philosophy, respect for nourishment, and real convenience culture protect them from the same fate. Discover how to take back your health, unsubscribe from the “sick-care” model, and reclaim your energy, confidence, and freedom. 📌 Reserve your spot here: https://bit.ly/4gMLN5z  Support Real Food for Kids 🍎 👉Check out and support the Soul West Foundation, dedicated to bringing real food to U.S. schools: https://www.sol-west.org/ 🔎 Find all of the Metabolic Freedom Sponsorship deals and coupon codes here: https://www.ketokamp.com/sponsorship-deals

30 Sep 15min

#1113 Eat Your Way to Fasting Results – The Incredible Secret to Slowing Aging with Dr. Chris Rhodes

#1113 Eat Your Way to Fasting Results – The Incredible Secret to Slowing Aging with Dr. Chris Rhodes

In this episode of the Metabolic Freedom Podcast, Ben Azadi sits down with Dr. Chris Rhodes, PhD—scientist, CEO of Mimio, and one of the brightest minds in the longevity space. Together, they dive into the fascinating world of fasting and cellular health, unpacking how simple lifestyle choices can literally change the way your body ages. You’ll discover the science of fasting mimetics—supplements designed to give you many of fasting’s benefits without skipping meals—and hear how Dr. Rhodes and his team are pushing the boundaries of anti-aging research. From boosting metabolism and immune function to extending lifespan, the conversation blends cutting-edge science with practical, real-world strategies you can use right away. Along the way, Dr. Rhodes shares clinical results, what makes Mimo’s formulation unique, and his vision for the future of longevity science. The episode wraps with a personal reflection on gratitude and wellness, reminding us that the pursuit of health isn’t just about adding years to your life—it’s about adding life to your years. 🔗 Links and Resources: Get Mimio - benazadi.com/mimio - 20% off your first purchase with Code: Keto Kamp Chris on LinkedIn Chris on Instagram 📖 Grab my bestselling book Metabolic Freedom for free bonuses →http://www.metabolicfreedombook.com

29 Sep 51min

#1112 Doctors Can’t Explain This: The Life-Changing Benefits of Fasting 16 Hours a Day and How It Resets Your Body With Ben Azadi

#1112 Doctors Can’t Explain This: The Life-Changing Benefits of Fasting 16 Hours a Day and How It Resets Your Body With Ben Azadi

In this episode of the Metabolic Freedom Podcast, Ben Azadi reveals what really happens when you fast for 16 hours a day. Forget dieting—this is a full-body reset. You’ll discover: Why cravings fade and visceral fat melts within 30 days How your metabolism shifts into fat-burning mode in 90 days The power of autophagy, human growth hormone, and reduced inflammation What a full year of fasting does for your brain, immune system, and body composition This is the roadmap to metabolic flexibility, better focus, and lasting fat loss. Resources & Links Mentioned: 🔥 Free Fat Loss Masterclass → https://bit.ly/48mviLx  ☕ My go-to coffee: Purity Coffee → http://ketokampcoffee.com  (use code KETOCAMP for 15% off) 📊 Test autophagy with Keto-Mojo → http://ketokampmachine.com  📖 Grab my bestselling book Metabolic Freedom for free bonuses →http://www.metabolicfreedombook.com   🔎 Find all of the Metabolic Freedom Sponsorship deals and coupon codes here: https://www.ketokamp.com/sponsorship-deals

28 Sep 23min

#1111 7 Weird Signs You’re Actually Burning Fat (Even When the Scale Says Otherwise) With Ben Azadi

#1111 7 Weird Signs You’re Actually Burning Fat (Even When the Scale Says Otherwise) With Ben Azadi

Most people quit their fat loss journey too soon because the early signs look like failure. In this episode, Ben Azadi reveals 7 surprising indicators that your metabolism is burning fat, even when the scale goes up. You’ll learn: Why the scale lies and what to track instead. How increased urination, thirst, and even funky breath signal fat burning. What mood swings, bloating, and sleep changes really mean. The role of protein, electrolytes, and gut health in supporting the transition. A bonus tip: why skin tags falling off is a powerful metabolic clue. Ben also shares practical tools like the Keto Kamp Cocktail, binders for detox, magnesium for sleep, and why gratitude (Vitamin G) is your fat-burning ally. 🎯 Key takeaway: These “weird” symptoms aren’t setbacks, they’re proof your body is finally switching to fat-burning mode. ‼️Resources & Links Mentioned‼️ 👉Gut Clear: https://bit.ly/42JpGXO  👉BiOptimizers Magnesium: https://bioptimizers.com/shop/products/masszymes?gl=6722995c3f5d60566a8b4571&coupon=ketokamp10&hbanner=1&vtid=vip-pdp&ptp=1  👉InBody Body Fat Scale: https://amzn.to/4eDRTUR  👉Oura Ring (for sleep tracking): https://amzn.to/46vf69y, https://ouraring.com/discount/6e9615cebf?utm_medium=iac_raf  👉Join Ben’s Free Fat Loss Webinar: https://bit.ly/4pJ5MpP  🔎 Find all of the Metabolic Freedom Sponsorship deals and coupon codes here: https://www.ketokamp.com/sponsorship-deals

27 Sep 16min

#1110 The Truth About Man Boobs: Estrogen, Testosterone, and the Simple Lifestyle Fixes That Work With Ben Azadi

#1110 The Truth About Man Boobs: Estrogen, Testosterone, and the Simple Lifestyle Fixes That Work With Ben Azadi

If you’ve been trying to lose weight but still struggle with stubborn chest fat, this episode is for you. Ben Azadi shares the real reasons behind “man boobs” — and it’s not just about calories. Everyday habits like drinking beer, using plastics, and poor sleep are disrupting your hormones and fueling fat storage. You’ll discover Ben’s proven 5-step protocol to flatten your chest, boost testosterone, and burn fat naturally: Ditch the beer and toxic alcohols. Remove plastics and xenoestrogens. Optimize sleep for testosterone and growth hormone. Focus on compound strength training. Activate brown fat with cold exposure, heat therapy, and sprints. Ben also answers listener questions on safe alcohol choices, estrogen-detox foods, strength training results, and more. 🔥Free Masterclass: 👉 Reserve your free spot at  https://bit.ly/4pAbBWJ  🔎 Find all of the Metabolic Freedom Sponsorship deals and coupon codes here: https://www.ketokamp.com/sponsorship-deals

25 Sep 18min

#1109 Doctors Lied. THIS Is the Real Cause of Belly Fat (Not Sugar or Carbs) - Ben Azadi Keynote

#1109 Doctors Lied. THIS Is the Real Cause of Belly Fat (Not Sugar or Carbs) - Ben Azadi Keynote

FREE Fat Loss Masterclass — Burn Fat Without Dieting (SAVE YOUR SPOT) - https://bit.ly/3IeUBo5 See Ben's upcoming keynote tour here: http://www.benazadi.com/events In this episode, Ben Azadi exposes the truth behind obesity and chronic disease. It’s not sugar — it’s cellular inflammation. Learn why doctors got it wrong, how seed oils stay trapped in your body for years, and why your thoughts and gratitude can literally reshape your DNA. Plus, discover the power of personal responsibility, goal setting, and “Vitamin G” to unlock lasting health and metabolic freedom. 🔎 Find all of the Metabolic Freedom Sponsorship deals and coupon codes here: https://www.ketokamp.com/sponsorship-deals

23 Sep 1h 4min

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