Sam Apple | The Connection Between Glucose, Insulin & Cancer KKP: 344

Sam Apple | The Connection Between Glucose, Insulin & Cancer KKP: 344

Today, I am blessed to have here with me Sam Apple. He is on the faculty of the MA in Science Writing and MA in Writing programs at Johns Hopkins. Prior to his arrival at Johns Hopkins, Apple taught creative writing and journalism at the University of Pennsylvania for ten years. He holds a BA in English and Creative Writing from the University of Michigan and an MFA in Creative Nonfiction from Columbia University. Apple is the author of Ravenous American Parent, and Schlepping Through the Alps. He has published short stories, personal essays, satires, and journalistic features on a wide range of topics. In recent years, he has primarily written about science and health. His work has appeared in The New York Times Magazine, The New Yorker, The Atlantic, Wired, The Los Angeles Times, The Financial Times Magazine, ESPN The Magazine, The MIT Technology Review, and McSweeney’s, among many other publications. Schlepping Through the Alps was a finalist for the PEN America Award for a first work of nonfiction. In this episode, Sam talks about the inspiration behind his book Ravenous: Otto Warburg, the Nazis, and the Search for the Cancer-Diet. We dive into Otto Warburg’s work and how the Nazis protected him for his cancer science. Sam explains how sugar can promote cancer growth and what steps you can take to lower your insulin levels. Tune in as we chat about fasting, therapies for cancer, and the importance of exercise. Get Sam’s book here: https://www.amazon.com/Ravenous-Warburg-Search-Cancer-Diet-Connection/dp/1631493159/benazadi-20 Order Keto Flex: http://www.ketoflexbook.com -------------------------------------------------------- / / E P I S O D E S P ON S O R S PureForm Omega Plant Based Oils (Best Alternative to Fish Oil): http://www.purelifescience.com Use ben4 for $4.00 off. Upgraded Formulas Hair Mineral Deficiency Analysis & Supplements: http://www.upgradedformulas.com Use BEN10 at checkout for 10% off your order. Paleo Valley beef sticks, apple cider vinegar complex, organ meat complex & more. Use the coupon code KETOKAMP15 over at https://paleovalley.com/ to receive 15% off your entire order. Text me the words "Podcast" +1 (786) 364-5002 to be added to my contacts list. [00:30] The Inspiration Behind Ravenous: Otto Warburg, the Nazis, and the Search for the Cancer-Diet Read Ravenous: Otto Warburg, the Nazis, and the Search for the Cancer-Diet Connection: https://www.amazon.com/Ravenous-Warburg-Search-Cancer-Diet-Connection/dp/1631493159/benazadi-20 Sam was interested in researching metabolic disease and metabolic health. Plus, Gary Taubes inspired him. Sam was really surprised to learn that that cancer was associated with diabetes, insulin resistance, obesity, and cardiovascular disease. He wanted to dig further on the connection between cancer and metabolic disease. [02:10] The Nazis Protected Warburg For His Cancer Research In 1923, Warburg makes this famous discovery called the Warburg Effect. Cancer cells take up a lot more glucose than other cells and burn it without oxygen; they ferment it, just like microorganisms do. Warburg also has made other discoveries about how cells breathe and use oxygen. He wins the Nobel Prize in 1931. In 1933, the Nazis come along. Despite having a Jewish father and being openly gay, the Nazis protected Warburg because they were interested in his cancer research. [06:50] Warburg’s Studies Started To Disappear After The War After the war, Warburg’s cancer research really starts to disappear. Australia in the 1950s famously discovered the structure of DNA. Eventually, we had a new sort of genetic understanding of cancer where we can now identify specific mutations. So, how cells take up glucose and shift their metabolism was considered irrelevant because of the study of genetics. Warburg’s studies take peoeple back to diet, and there’s a huge bias against taking diet seriously. [12:20] What Sugar Does To Promote Cancer Growth If cancer is about these metabolic shifts inside of a cell, what is it about the way we eat that affects the way a cell eats? In America, one out of three women are diagnosed with cancer within their lifetime. For men, it's about one in two. Cancer is closely linked to obesity. 13 of the deadliest cancers have been solidly linked to obesity. Sam wanted to know if obesity was causing cancer or if something was driving both. Elevated levels of the hormone insulin are responsible for obesity and give microscopic cancers a chance to grow and thrive. What is it about our diet that causes insulin to rise? Sugar! The increase in sugar consumption maps pretty closely to the rise of diabetes, heart disease, and cancer. [19:30] How A Keto Diet That Will Help You Prevent Cancer Sam is a huge believer that keto is a logical way to prevent cancer. The single most important thing you can do to improve your odds for cancer prevention is to keep your insulin levels low. Hyperinsulinemia promotes the growth of cancer. So, it’s important to follow a diet that keeps your insulin levels down. [22:20] Intermittent Fasting Is Another Great Way To Lower Insulin Intermittent fasting is one very successful strategy for keeping insulin down. If you can fast consistently, it seems to work quite effectively on lowering insulin. Fasting can lead to weight loss because it lowers insulin levels in the body. Sam wants to point out that thin people can still have insulin resistance. In some ways, being naturally thin can actually be a disadvantage because you can't store subcutaneous fat. [26:30] How To Optimize Insulin and Glucose Levels To Be Proactive Instead of Reactive You can't outrun a bad diet. However, exercise can help you feel better and make you more inspired to follow a low-carb diet. After workouts, you can be inspired to eat healthily and continue to feel good. Once you understand that sugar is linked to cancer, it should help you ditch it during mealtime. [38:30] Finding Therapies To Target Specific Cancer Mutations When cancer can eat lots of glucose, it's no longer thinking about dying; it's thinking about doing a lot more things. Based on which particular mutation you have, the oncologist will devise a treatment. Unfortunately, targeted therapies to specific mutations haven't been as successful as we would have liked. However, there are some cases where therapies will successfully target mutations. [42:25] The Best Preventative Measures To Preventing Cancer In The Future Eliminate sugar from your diet. Definitely eliminate liquid sugar from your diet. If you are insulin resistant, you need to reduce those insulin levels. Stop smoking. Cut out refined carbohydrates. AND MUCH MORE! Resources from this episode: Check out Sam’s Website: http://samapple.com/ Read Ravenous: Otto Warburg, the Nazis, and the Search for the Cancer-Diet Connection: https://www.amazon.com/Ravenous-Warburg-Search-Cancer-Diet-Connection/dp/1631493159/benazadi-20 Follow Sam Apple Twitter: https://twitter.com/sam_apple1 Instagram: https://www.instagram.com/samapplebooks/ Join theKeto Kamp Academy: https://ketokampacademy.com/7-day-trial-a WatchKeto Kamp on YouTube: https://www.youtube.com/channel/UCUh_MOM621MvpW_HLtfkLyQ Order Keto Flex: http://www.ketoflexbook.com -------------------------------------------------------- / / E P I S O D E S P ON S O R S PureForm Omega Plant Based Oils (Best Alternative to Fish Oil): http://www.purelifescience.com Use ben4 for $4.00 off. Upgraded Formulas Hair Mineral Deficiency Analysis & Supplements: http://www.upgradedformulas.com Use BEN10 at checkout for 10% off your order. Paleo Valley beef sticks, apple cider vinegar complex, organ meat complex & more. Use the coupon code KETOKAMP15 over at https://paleovalley.com/ to receive 15% off your entire order. Text me the words "Podcast" +1 (786) 364-5002 to be added to my contacts list. *Some Links Are Affiliates* // F O L L O W ▸ instagram | @thebenazadi | http://bit.ly/2B1NXKW ▸ facebook | /thebenazadi | http://bit.ly/2BVvvW6 ▸ twitter | @thebenazadi http://bit.ly/2USE0so ▸clubhouse | @thebenazadi Disclaimer: This podcast is for information purposes only. Statements and views expressed on this podcast are not medical advice. This podcast including Ben Azadi disclaim responsibility from any possible adverse effects from the use of information contained herein. Opinions of guests are their own, and this podcast does not accept responsibility of statements made by guests. This podcast does not make any representations or warranties about guests qualifications or credibility. Individuals on this podcast may have a direct or non-direct interest in products or services referred to herein. If you think you have a medical problem, consult a licensed physician.

Episoder(1128)

#1085 The Hidden McDonald’s Ingredient That Acts Like Cigarettes in Your Body — How Seed Oils Destroy Your Gut, Fuel Inflammation, and Trigger Belly Fat With Ben Azadi

#1085 The Hidden McDonald’s Ingredient That Acts Like Cigarettes in Your Body — How Seed Oils Destroy Your Gut, Fuel Inflammation, and Trigger Belly Fat With Ben Azadi

McDonald’s isn’t just unhealthy because of sugar, salt, or calories—the real danger is hidden in the oils and additives they use. In this episode, Ben Azadi reveals the shocking truth about McDonald’s ingredients that silently destroy your gut, fuel chronic inflammation, and lead to stubborn belly fat. You’ll learn how the oils in McDonald’s fries create the same toxic compounds as cigarette smoke, why these bad fats can stay in your body for years, and how other additives in nuggets, buns, and sauces wreak havoc on your gut microbiome and hormones. Ben also shares his go-to fast-food alternative, the exact order he chooses when in a pinch, and the best strategies to detox from these harmful oils and protect your metabolism. 👇Resources Mentioned in This Episode: 📘 Metabolic Freedom (my latest book) – http://www.metabolicfreedombook.com   🛒 Free Keto Camp Blueprint Grocery Shopping Guide → https://bit.ly/45BWqmw  🎤 Check out my Metabolic Freedom Book Tour & Events → http://benazadi.com/events  🔎 Find all of the Metabolic Freedom Sponsorship deals and coupon codes here: https://www.ketokamp.com/sponsorship-deals

21 Aug 15min

#1084 The Hidden Metabolism Blocker After 40 That Doctors Never Mention (And How to Fix It for Rapid Fat Loss) With Ben Azadi

#1084 The Hidden Metabolism Blocker After 40 That Doctors Never Mention (And How to Fix It for Rapid Fat Loss) With Ben Azadi

Struggling with stubborn belly fat after 40? The problem isn’t your diet or lack of willpower—it’s inflamed cell membranes blocking fat-burning hormones, nutrients, and detox pathways. In this episode, Ben Azadi reveals how to repair your metabolism by: Adding phosphatidylcholine-rich foods and supplements to rebuild cell membranes Replenishing minerals and electrolytes to keep cells charged Prioritizing deep delta sleep for overnight fat-burning repair Removing hidden inflammatory triggers like seed oils, refined carbs, toxins, and artificial sweeteners Restoring mitochondrial function with intermittent fasting, HIIT, and targeted superfoods You’ll also learn why calories aren’t the real problem, how to protect your hormones, and the daily habits that can help you finally burn stubborn belly fat. ✔️Free Resource & Links 🔥Download Ben’s FREE ebook: 3 Easy Steps to Lose 10 Pounds in 7 Days → https://bit.ly/4mrbElK  👉Inbody Scale: https://amzn.to/4eDRTUR  👉CoQ10:https://amzn.to/4fBnMh6 👉 PQQ:https://amzn.to/47xS1DG 👉Magnesium glycinate: https://amzn.to/3Ux3AmY 👉Beam Minerals: https://www.beamminerals.com/?oid=1&affid=549  👉Electrolites: http://www.ketokampsalt.com use code AZADI  👉BodyBio: https://bodybio.com/?ref=KETOKAMP  📚Learn more in Ben’s latest book Metabolic Freedom:http://www.metabolicfreedombook.com  👉See Ben’s live event schedule: http://benazadi.com/events  🔎 Find all of the Metabolic Freedom Sponsorship deals and coupon codes here: https://www.ketokamp.com/sponsorship-deals

19 Aug 19min

#1083 The Secret Fat-Burning Hormone Doctors Ignore – Unlock Metabolism & Energy with Dr. Rebecca Warren

#1083 The Secret Fat-Burning Hormone Doctors Ignore – Unlock Metabolism & Energy with Dr. Rebecca Warren

In this episode, Ben Azadi is joined by thyroid expert Dr. Rebecca Warren for a special live masterclass on thyroid health. If you’ve ever struggled with fatigue, stubborn weight, or feeling “off” despite normal lab results, this conversation is for you. Dr. Warren breaks down how thyroid hormones—especially T3—are the real drivers of your metabolism, energy, and weight loss. She explains why standard thyroid tests often miss hidden issues and shares practical strategies you can use to support healthy thyroid function. You’ll also learn how environmental toxins affect your hormones, and why your thyroid, adrenals, and sex hormones are all connected. Through science, personal stories, and clear action steps, this episode offers both clarity and hope for anyone looking to finally get to the root of their metabolic struggles. 🔥 Topics Discussed: Importance of thyroid health in metabolism and overall well-being. Role of the active thyroid hormone T3 in energy production and fat burning. Common issues with standard thyroid testing, particularly the reliance on TSH levels. Interconnectedness of thyroid hormones with adrenal and sex hormones. Symptoms and signs of low T3 hormone, including weight loss resistance and fatigue. Link between thyroid health and insulin resistance or diabetes. Discussion on the prevalence of hypothyroidism and autoimmune thyroid diseases. Environmental factors and toxins contributing to thyroid dysfunction. Lifestyle strategies for optimizing thyroid health, including water quality and mineral support. Importance of comprehensive thyroid testing beyond TSH for accurate diagnosis and treatment. 🔗 Links and Resources: Dr. Warren's Website Dr. Warren on Instagram Dr. Warren on Facebook Dr. Warren on YouTube Dr. Warren's Podcast The Thyroidless Life 📚Learn more in Ben’s latest book Metabolic Freedom:http://www.metabolicfreedombook.com  👉See Ben’s live event schedule: http://benazadi.com/events 🔎 Find all of the Metabolic Freedom Sponsorship deals and coupon codes here: https://www.ketokamp.com/sponsorship-deals

18 Aug 58min

#1082 The Surprising Science of Creatine: How This Simple Powder Melts Fat, Builds Muscle, and Boosts Brain Power With Ben Azadi

#1082 The Surprising Science of Creatine: How This Simple Powder Melts Fat, Builds Muscle, and Boosts Brain Power With Ben Azadi

Ben Azadi breaks down why creatine monohydrate is more than just a gym supplement—it’s a powerhouse for muscle growth, fat loss, brain health, mood, and energy. Learn how creatine works as a “cellular energy buffer” to recharge your mitochondria, improve insulin sensitivity, and boost mental performance, especially under stress or poor sleep. Ben shares: How creatine enhances lean muscle mass and burns more fat at rest Cognitive benefits for memory, focus, and mood His travel protocol to crush jet lag Exact dosages for men, women, and older adults Safety tips, hydration guidance, and the best creatine form to buy Links mentioned: Free Burn Fat eBook: https://bit.ly/4mlkLEp  Speaking tour: http://benazadi.com/events  Ben’s recommended creatine monohydrate powder: https://amzn.to/3Hdcy5Y  🔎 Find all of the Metabolic Freedom Sponsorship deals and coupon codes here: https://www.ketokamp.com/sponsorship-deals

17 Aug 16min

#1081 7-Step Fat-Burning Protocol to Transform Your Body After 40—Without Dieting or Exercise With Ben Azadi

#1081 7-Step Fat-Burning Protocol to Transform Your Body After 40—Without Dieting or Exercise With Ben Azadi

In this episode of the Metabolic Freedom Podcast, Ben Azadi shares a 7-step protocol to burn stubborn fat after 40—without dieting or intense exercise.  You’ll discover how simple daily habits like grounding, walking after meals, boosting oxytocin, and improving sleep can lower inflammation, balance hormones, and reset your metabolism.  Ben also explains why protein and fat—not calorie counting—are key to long-term fat loss, the benefits of morning sunlight for circadian health, and how hydration with electrolytes jumpstarts your day. Backed by science and easy to implement, these strategies help you burn fat naturally at any age. Free eBook →https://bit.ly/45AKul9 Event dates → http://benazadi.com/events  Metabolic Freedom Book → http://www.metabolicfreedombook.com

16 Aug 17min

#1080 How a 72-Hour Fast Melts Belly Fat, Regenerates Stem Cells, and Resets Your Brain – With Ben Azadi

#1080 How a 72-Hour Fast Melts Belly Fat, Regenerates Stem Cells, and Resets Your Brain – With Ben Azadi

In this solo episode, Ben Azadi reveals the science-backed benefits of a 72-hour water fast and why day 3 is the key to burning dangerous visceral fat.  He walks through what happens at every stage of the fast — from increased human growth hormone and ketone production to stem cell regeneration and a dopamine reset.  Ben also shares who should avoid long fasts, how to break a fast correctly, and answers the most common fasting questions. Resources Mentioned: Free 30-day belly fat plan: https://bit.ly/4l5CdLu  Metabolic Freedom Book + Tour Dates: http://benazadi.com/events  Beam Minerals: https://www.beamminerals.com/?oid=1&affid=549 20% off with code “KETOKAMP” Purity Coffee: http://ketokampcoffee.com Use code "KETOKAMP" for 15% off Equip Protein: http://equipfoods.com/benazadi Use code "BENAZADI" for 20% off Kettle & Fire Bone Broth:  https://www.kettleandfire.com/?afmc=ketokamp  use code "KETOKAMP" Fasting Apps: Zero, LIFE 🔎 Find all of the Metabolic Freedom Sponsorship deals and coupon codes here: https://www.ketokamp.com/sponsorship-deals

14 Aug 18min

#1079 The Truth About Cheese: What to Avoid and What to Eat for Fat Loss, Energy, and a Healthier Gut With Ben Azadi

#1079 The Truth About Cheese: What to Avoid and What to Eat for Fat Loss, Energy, and a Healthier Gut With Ben Azadi

Ben breaks down the cheeses that can sabotage your metabolism and the ones that can boost fat burning, lower inflammation, and support gut health. You’ll discover why 75% of people react poorly to certain dairy proteins and lactose, the dangers of processed and low-fat cheeses, and the nutrient-rich, A2 casein cheeses that have been enjoyed for centuries without harm. Highlights: 7 cheeses to avoid: American, ricotta, low-fat/flavored cottage cheese, cream cheese, cow-based mozzarella, brie, and blue cheese. 5 best options: Goat cheese, sheep cheese, aged Parmesan, goat’s milk feta, and organic grass-fed ghee. Why vegan cheese alternatives often harm gut health. The benefits of raw, grass-fed, unpasteurized dairy. How dairy can impact skin health, weight loss, and inflammation. Resources & Links: Free Burn Fat E-Book: https://bit.ly/3V19Gfr  Ben’s events & speaking schedule: http://benazadeh.com/events  🎁  Purchase Ben's new book Metabolic Freedom: http://www.metabolicfreedombook.com  🔎 Find all of the Metabolic Freedom Sponsorship deals and coupon codes here: https://www.ketokamp.com/sponsorship-deals

12 Aug 16min

#1078 The Invisible Stress Destroying Your Metabolism – And How to Stop It Fast with Todd Shipman

#1078 The Invisible Stress Destroying Your Metabolism – And How to Stop It Fast with Todd Shipman

On this episode, Ben Azadi sits down with quantum wellness expert Todd Shipman for a fascinating deep dive into the unseen forces affecting your health—electromagnetic fields (EMFs) and quantum energy. Todd shares his personal journey and reveals how Leela Quantum’s cutting-edge tools, like the Infinity Block and Quantum Upgrade, are designed to shield the body from EMF stress, supercharge your mitochondria, and boost heart rate variability. Think of it as creating a “protective bubble wrap” around your body—helping you feel calmer, more energized, and better equipped to thrive in today’s tech-saturated world. Backed by compelling science and real-world stories, this conversation offers practical ways to protect your health, optimize your metabolism, and live with less stress—even when you’re surrounded by screens and devices. 🔥 Topics Discussed: Impact of electromagnetic fields (EMFs) on human health and metabolism. Role of quantum energy in enhancing mitochondrial function and overall well-being. Protective effects of quantum energy against environmental stressors. Scientific studies supporting the benefits of Leela Quantum products. Mechanisms of ATP production and heart rate variability improvement. Personal experiences and skepticism surrounding quantum wellness. Discussion of innovative quantum wellness products, including EMF-blocking clothing. Techniques for measuring the effects of EMFs and quantum energy on the body. Concept of hormesis and its relation to stress management and health. Customizable quantum energy services for personal and environmental protection. 🔗 Links and Resources: Get Leela Quantum Products Follow Leela on Instagram The Hidden Messages in Water by Masaru Emoto 📍 Ben’s speaking tour & book signings → http://benazadi.com/events  👉 http://metabolicfreedombook.com 🔎 Find all of the Metabolic Freedom Sponsorship deals and coupon codes here: https://www.ketokamp.com/sponsorship-deals

11 Aug 51min

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