Nasal Vaccine for Alzheimer’s Disease Enters Clinical Trial
Dementia Matters20 Jan 2022

Nasal Vaccine for Alzheimer’s Disease Enters Clinical Trial

In November 2021, Brigham and Women’s Hospital in Boston launched the first human trial of a nasal vaccine for Alzheimer’s disease. Nearly 20 years of research went into developing the vaccine, which uses the immune system to clear Alzheimer’s disease-related proteins from the brain. Lead researcher Dr. Howard Weiner joins the podcast to discuss the science behind the vaccine and how it could introduce new ways of treating other neurodegenerative diseases in the future.

Guest: Howard Weiner, MD, professor of neurology, Harvard Medical School, co-director, Ann Romney Center for Neurologic Diseases, Brigham and Women’s Hospital

Episode Topics

How does the vaccine work?

Why would a vaccine be a potentially better approach to treatment than a monoclonal antibody?

Do you think a vaccine could ever be used for prevention reasons instead of treatment?

Why a nasal vaccine versus into the muscle, like the COVID vaccine or flu vaccine?

Show Notes

Learn more about Brigham and Women’s Hospital’s nasal vaccine trial at their press release.

For those interested in participating in the study, you can call the Ann Romney Center for Neurologic Diseases at Brigham and Women's Hospital at 617-723-5588 or email protollinstudy@bwh.harvard.edu.

Watch Dr. Weiner’s film, What is Life?, The Movie, on YouTube.

Learn more about Dr. Weiner’s film, Abe and Phil’s Last Poker Game, on IMDb.

Denne episoden er hentet fra en åpen RSS-feed og er ikke publisert av Podme. Den kan derfor inneholde annonser.

Episoder(242)

How Dementia Caregiving Affects the Spousal Caregiver

How Dementia Caregiving Affects the Spousal Caregiver

Caring for those with dementia represents a major public health challenge, with caregivers, especially spouses, providing long-term, largely unpaid care. With caregiving stress linked to a decline in ...

28 Jul 39min

Managing the Medicine Cabinet: How Prescriptions Impact Cognition and Brain Health as We Age

Managing the Medicine Cabinet: How Prescriptions Impact Cognition and Brain Health as We Age

Prescription medications, over-the-counter drugs and supplements are incredibly common among older adults, yet many of these routine treatments can unexpectedly impact cognitive function and brain hea...

14 Jul 35min

Taking a Deep Dive into Subjective Cognitive Decline

Taking a Deep Dive into Subjective Cognitive Decline

Dr. Jessen returns to the podcast to take a deeper dive into subjective cognitive decline (SCD). Aiming to cover everything relating to SCD, Dr. Jessen shares insights in prognosis, risk factors and h...

7 Jul 17min

Defining Subjective Cognitive Decline

Defining Subjective Cognitive Decline

Subjective cognitive decline (SCD) can be one of the earliest noticeable signs of Alzheimer's disease, yet SCD is not yet fully understood. To help us understand more, Dr. Frank Jessen, an expert in t...

30 Jun 30min

SPRINT to a Healthy Mind: How Blood Pressure Control Affects Brain Health and Dementia Risk

SPRINT to a Healthy Mind: How Blood Pressure Control Affects Brain Health and Dementia Risk

Geriatrician Dr. Mark Supiano joins the podcast to discuss the connection between heart and brain health. Citing multiple clinical trials, he breaks down what these studies and their findings mean for...

18 Jun 40min

Addressing Cochrane’s Review on Amyloid-Targeting Treatments for Alzheimer’s Disease

Addressing Cochrane’s Review on Amyloid-Targeting Treatments for Alzheimer’s Disease

Amyloid-targeting monoclonal antibody treatments have ushered in a new era of Alzheimer’s disease therapies after decades of research and clinical trials. A recent review published by Cochrane, a glob...

4 Jun 44min

What to Expect from ‘When Memory Fades’ with Drs. Art Walaszek and Nathaniel Chin

What to Expect from ‘When Memory Fades’ with Drs. Art Walaszek and Nathaniel Chin

Guest host Dr. Art Walaszek takes over the podcast to interview Dr. Chin about his upcoming book, When Memory Fades. In addition to discussing the importance of dementia research and other clinical to...

19 Mai 32min

New Study Examines the Effects of Food Insecurity on Dementia Risk

New Study Examines the Effects of Food Insecurity on Dementia Risk

The latest Household Food Security report estimated that 13.7% of U.S. households experienced food insecurity in 2024. This lack of access to a nutritious diet can significantly affect health, so how ...

5 Mai 26min

Populært innen Vitenskap

fastlegen
tingenes-tilstand
forskningno
rekommandert
liberal-halvtime
jss
sinnsyn
villmarksliv
abels-tarn
fjellsportpodden
dekodet-2
rss-nysgjerrige-norge
tomprat-med-gunnar-tjomlid
hva-er-greia-med
rss-rekommandert
rss-inn-til-kjernen-med-sunniva-rose
grunnstoffene
mer-enn-hjerne
diagnose
kvinnehelsepodden