Dementia Researcher Blogs12 Mar 2025

Rahul Sidhu - My PhD: Neurovascular effects of heart disease in Alzheimer's

Rahul Sidhu, narrating a new blog he wrote for the Dementia Researcher website.

Rahul's blog explores his research and the connection between heart disease and Alzheimer's disease, focusing on how vascular dysfunction may accelerate cognitive decline. He explains the importance of neurovascular coupling, the role of tau protein tangles, and how conditions like atherosclerosis impact brain health. Using preclinical models, his research investigates whether impaired blood flow worsens Alzheimer’s progression, highlighting the potential for new treatments that improve vascular health as a way to slow or prevent dementia.

Find the original text, and narration here on our website.

https://www.dementiaresearcher.nihr.ac.uk/blog-my-phd-neurovascular-effects-of-heart-disease-in-alzheimers/

Rahul Sidhu is a PhD student at The University of Sheffield, focusing on the effects of heart disease on dementia in preclinical models of Alzheimer's disease. His research aims to uncover how cardiovascular health influences neurodegenerative conditions, potentially leading to novel therapeutic strategies. Find Rahul on LinkedIn

Enjoy listening? We're always looking for new bloggers, drop us a line. http://www.dementiaresearcher.nihr.ac.uk

This podcast is brought to you in association with Alzheimer's Association, Alzheimer's Research UK, Alzheimer's Society and Race Against Dementia, who we thank for their ongoing support.

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