285: CRISPR history, biotech struggles, & a big week for deals

285: CRISPR history, biotech struggles, & a big week for deals

With the first CRISPR-based medicine expected to win FDA approval any minute now, STAT’s Megan Molteni joins us to discuss how we got here and what it means for the future. Then, Bruce Booth from Atlas Venture joins us to discuss what was yet another downbeat year for biotech and whether there’s reason for optimism heading into 2024. To keep up with biotech news throughout the week, here's where you can subscribe to our newsletter, The Readout.

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Episoder(417)

Why two promising heart drugs flopped and what's next

Why two promising heart drugs flopped and what's next

On this week’s episode of “The Readout LOUD”: The pharma industry invested billions of dollars to develop drugs heralded as the next era in the treatment of heart disease — but why did they fail? And ...

10 Sep 30min

411: Capricor's data clash and a fugitive in the C-suite

411: Capricor's data clash and a fugitive in the C-suite

Is the Food and Drug Administration taking inconsistent approaches to Duchenne muscular dystrophy drugs? How will a new batch of drug executives shake up their companies? And why is Adam talking to a ...

30 Jul 36min

410: A father’s mission to save his daughter, and allegations on telehealth GLP-1 prescribing

410: A father’s mission to save his daughter, and allegations on telehealth GLP-1 prescribing

What does it take to develop a therapy for an ultra-rare disease? What are the allegations against a telehealth company that’s partnered with Novo Nordisk? And has a wanted fugitive been posing as a b...

23 Jul 1h 4min

409: Predicting biotech clinical trials & a new Alzheimer's drug controversy

409: Predicting biotech clinical trials & a new Alzheimer's drug controversy

On this week’s episode of "The Readout LOUD": The Kalshi prediction markets are coming for biotech, plus the controversy over an experimental Alzheimer’s disease treatment from Biogen. Kalshi, the ma...

16 Jul 35min

408: Whistleblower takes on health insurance and FDA commissioner candidates

408: Whistleblower takes on health insurance and FDA commissioner candidates

Why does getting family health insurance through a job cost as much as buying a new car? How did a whistleblower take on an insurance contractor? And who might be the new Food and Drug Administration ...

9 Jul 43min

407: The mysterious case of Eli Lilly's obesity drug

407: The mysterious case of Eli Lilly's obesity drug

Who got exclusive access to Eli Lilly's highly anticipated obesity candidate? Why are drugmakers spending so much money on acquisitions? And are hair loss drugs a good investment? We discuss all that...

25 Jun 42min

406: New hope in treating Huntington's disease and a report card on RFK Jr.'s promises

406: New hope in treating Huntington's disease and a report card on RFK Jr.'s promises

This week: New hope for people living with Huntington’s disease, and a report card on RFK Jr.’s effort to remake health in America.  The Food and Drug Administration reversed its opposition to a clos...

18 Jun 36min

405: An obesity drug deep-dive, and peptides move mainstream

405: An obesity drug deep-dive, and peptides move mainstream

Can any of the new obesity medications in development stand out from the pack? Which company just broke records with its IPO? And will the Food and Drug Administration allow greater access to experime...

11 Jun 36min

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