Moderna and Flagship Pioneering: Noubar Afeyan

Moderna and Flagship Pioneering: Noubar Afeyan

In the field of bio-tech, it can take 10 years and millions of dollars to see if an experimental idea might turn into a life-saving treatment—if it ever does. Noubar Afeyan fully understood those risks when he co-founded Moderna in 2010. He and his colleagues were looking for a way to deploy the messenger RNA molecule to tackle life-threatening diseases. In January of 2020, an urgent opportunity presented itself in the form of a deadly virus that was spreading across the globe. At a breathtaking pace, Moderna produced a prototype for a COVID-19 vaccine, partnered with the NIH to test it, and produced millions of doses, becoming part of the most rapid vaccine roll-out in human history. While Moderna is the best known of Noubar's companies, he has launched many others in the bio-tech space as part of Flagship Pioneering, his multi-billion dollar venture studio. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Episoder(785)

How I Built Resilience: Live with Stewart Butterfield and Steve Holmes

How I Built Resilience: Live with Stewart Butterfield and Steve Holmes

Slack's co-founder Stewart Butterfield wonders what the future of work will look like for his 12 million customers. Springfree Trampoline's co-founder Steve Holmes says the company has seen a 300 percent increase in demand for its products. These conversations are excerpts from our How I Built Resilience series, where Guy talks online with founders and entrepreneurs about how they're navigating these turbulent times.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

9 Mai 202021min

How I Built Resilience: Live with Christina Tosi and Gary Erickson & Kit Crawford

How I Built Resilience: Live with Christina Tosi and Gary Erickson & Kit Crawford

Since March, only five of Milk Bar's 18 locations have been up and running, but founder Christina Tosi tells Guy she is determined to bring the joy of baking to the doorsteps of family, friends, and healthcare workers. Gary Erickson and Kit Crawford have donated more than 3 million Clif Bars to doctors and nurses during the COVID-19 crisis. They tell Guy about the importance of morale when running an essential business during a pandemic. These conversations are excerpts from our How I Built Resilience series, where Guy talks online with founders and entrepreneurs about how they're navigating these turbulent times.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

7 Mai 202029min

Cotopaxi: Davis Smith

Cotopaxi: Davis Smith

By his mid-30's, Davis Smith had co-founded two businesses. The first ended well, but the second was such a disappointment that he wondered if he should even bother trying again. But he did. In 2014, he launched Cotopaxi, an outdoor gear company with two fluffy llamas as mascots and an expressed mission to do good in the world. The brand is now making tens of millions of dollars a year, and Davis hopes that the current pandemic will not slow its ambitions to grow and to give back generously. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

4 Mai 20201h 5min

How I Built Resilience: Live with José Andrés

How I Built Resilience: Live with José Andrés

When chef José Andrés isn't running Michelin-starred restaurants, he's feeding the masses through World Central Kitchen, a nonprofit he founded that brings food to people during humanitarian crises. The COVID-19 crisis has shut down his restaurants indefinitely, but José is busier than ever leading the relief efforts of World Central Kitchen, which has served more than 3 million people to date. José talked to Guy as part of our How I Built Resilience series: weekly online conversations with founders and entrepreneurs about how they're navigating these turbulent times.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

30 Apr 202028min

Fitbit: James Park

Fitbit: James Park

In 2006, James Park had what he describes as a "lightning bolt" moment when he first used a Nintendo Wii. Fascinated by its motion-tracking controller, James wondered if you could take the technology out of the living room and into the streets. Three years later, he and co-founder Eric Friedman launched the Fitbit Tracker, which allowed users to track their steps and compare progress with others. Sales took off, and Fitbit dominated the wearables market until the Apple Watch came along, forcing James and Eric to re-imagine the brand. Today, against a cloudy economic backdrop, James hopes Fitbit can grow into its role as a health and wellness service. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

27 Apr 20201h 4min

How I Built Resilience: Live with Simon Sinek

How I Built Resilience: Live with Simon Sinek

Each week, Guy is hosting online conversations with founders and entrepreneurs about how they're navigating these turbulent times. Today's conversation is with Simon Sinek, whose books about business — including "Start with Why," and "The Infinite Game" — offer guidance to founders that is especially timely right now. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

23 Apr 202019min

Brooklinen: Vicki and Rich Fulop

Brooklinen: Vicki and Rich Fulop

On the first day of their Vegas vacation in 2012, Rich and Vicki Fulop sat down on their hotel bed and immediately had the same thought: "These sheets are really nice!" The fabric was the perfect blend of cool, crisp, and soft, but the sheets turned out to be way too expensive to buy. So, Vicki and Rich wondered if it was possible to make high-end linen at reasonable prices; linen that would appeal to a younger market, "not just our moms." After many stumbles, they built Brooklinen into a $100 million brand, and are hopeful they can withstand today's economic turbulence. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

20 Apr 20201h 9min

How I Built Resilience: Live with David Neeleman and Tristan Walker

How I Built Resilience: Live with David Neeleman and Tristan Walker

Each week, Guy will be hosting brief online conversations with founders and members of the How I Built This community about how they're navigating these uncertain times. This past week, Guy spoke with two former guests: David Neeleman of JetBlue Airways, and Tristan Walker of Walker & Company. David described how Azul Airlines, his Brazil-based company, has been directly impacted by the COVID-19 crisis, and Tristan explained how he's innovating from home. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

16 Apr 202020min

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