Episode 411: An Encouraging Clinical Trial for Progressive MS with Jason Tardio

Back in Episode #401, we reported promising results from a Phase 2 clinical trial for vidofludimus calcium and its impact on progressive MS. This therapy is being developed by Immunic Therapeutics, and this week, Jason Tardio, Immunic's President and Chief Operating Officer, joins me to share some of the specifics of that clinical trial.

Jason will also shed light on why Immunic believes that vidofludimus calcium goes beyond merely slowing disability, potentially offering vital neuroprotection for MS patients, making it a potential game-changer.

We're also sharing the encouraging results from a study that focused on the efficacy of neural stem cell transplantation as a remyelination therapy.

We'll tell you about a study in the U.K. that measured disability progression among people with MS five years after undergoing autologous hematopoietic stem cell transplantation (aHSCT).

You'll learn about an AI tool that can predict whether someone living with MS is likely to experience progression independent of relapse activity (PIRA) with a high degree of accuracy.

We'll tell you where you can catch the International Progressive MS Alliance webcast featuring a panel of experts discussing the future role of digital tools in MS research.

We'll explain how one of the less publicized aspects of the One Big Beautiful Bill Act will impact future MS care.

And Crush MS is less than two weeks away! We're sharing all the details!

We have a lot to talk about! Are you ready for RealTalk MS??!

This Week: Encouraging results from a clinical trial for progressive MS. :22

How a less-publicized aspect of the One Big Beautiful Bill Act will impact future MS patient care 1:18

A study looked at the efficacy of neural stem cell transplantation as a remyelination therapy 4:31

A study in the U.K. analyzed disability progression among people with MS five years after receiving autologous hematopoietic stem cell therapy (aHSCT) 7:42

Can AI accurately predict who will experience progression independent of relapse activity (PIRA)? 10:45

Don't miss the International Progressive MS Alliance webcast featuring experts discussing the future role of digital tools in MS research 12:40

Are you ready to support MS research while spending the afternoon in a Napa Valley vineyard? Get all the details to attend Crush MS 13:45

Jason Tardio, President and Chief Operating Officer of Immunic Therapeutics, discusses the recent Phase 2 clinical trial for vidofludimus calcium as a therapy for progressive MS 15:03

Share this episode 30:03

Have you downloaded the free RealTalk MS app? 30:23

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LINKS

If your podcast app doesn't allow you to click on these links, you'll find them in the show notes in the RealTalk MS app or at www.RealTalkMS.com

Become an MS Activist
https://nationalmssociety.org/advocacy

STUDY: Remyelination of Chronic Demyelinated Lesions With Directly Induced Neural Stem Cells
https://academic.oup.com/brain/advance-article/doi/10.1093/brain/awaf208/8185601

STUDY: Autologous Haemotopoietic Stem Cell Transplantation in the U.K.: A 20-Year Retrospective Analysis of Activity Haematological Outcomes from the British Society of Blood And Marrow Transplantation and Cellular Therapy
https://onlinelibrary.wiley.com/doi/epdf/10.1111/bjh.20199

STUDY: Deep Learning to Predict Progression Independent of Relapse Activity at a First Demyelinating Event
https://academic.oup.com/braincomms/article/7/4/fcaf243/8185588

WEBCAST: A Discussion From the International Progressive MS Alliance's Digital Tools Workshop
https://msif.org/news/2025/07/08/webcast-digital-tools

EVENT: Crush MS
https://crushms.org

Join the RealTalk MS Facebook Group
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RealTalk MS Episode 411
Guest: Jason Tardio

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