Hard: Little Pill, Big Pharma

Hard: Little Pill, Big Pharma

When Dr. Irwin Goldstein started his career in urology in the 1970s, he remembers asking his mentor—an early pioneer in penile implant surgeries—"How the hell does an erection occur in the first place?" His answer: 'We have absolutely no idea,'" Dr. Goldstein recalls. "So I said, okay, well, this is what I'm doing."  In this second episode of our three-part series, Hard, we dive into the medical and scientific advancements that led up to Viagra's FDA approval in 1998. From an unforgettable conference presentation...to an overnight drug study where an unexpected side effect kept popping up...we hear about the strange twists and turns that eventually led to a little blue pill, from some of the people who were there along the way. Plus, we explore the intentionality around the early marketing of Viagra—when former Senate Majority Leader Bob Dole encouraged men to summon the bravery to talk to their doctors—and we hear how that message has shifted over the years. This is the second episode of a three-part series. Listen to the first episode, about the impact of ED and Viagra on relationships, here. And look out for our episode next week, where we meet people for whom Viagra sparked deeper exploration about the meaning of good sex.

Episoder(150)

A Surgical Nurse On Being Essential

A Surgical Nurse On Being Essential

A few days ago we asked to hear from those of you who are essential workers—those of you who can’t stay home right now. We wanted to know what you are thinking about, and what’s helping you. And since...

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If You Can't Isolate, What Do You Need?

If You Can't Isolate, What Do You Need?

Over the last week, we've loved watching many of you use our Pandemic Tool Kit and learning how you're coping with social distancing. But not all of us have the ability to stay home right now. A liste...

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Confessions of a Nashville Power Couple

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In 2014, I talked with musicians Jason Isbell and Amanda Shires⁠ when they were a year into marriage, and two years into Jason's sobriety. But their new life didn't come without its challenges. Jason ...

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What Rockstars And Sober People Already Know About Quarantine

As social distancing becomes the new normal for all of us, it's affecting us in different ways. For a listener we're calling Chloe—who stopped drinking a year and a half ago—it's impacting the way she...

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We Made A Pandemic Tool Kit

We Made A Pandemic Tool Kit

In the past, we've created collaborative spreadsheets with your suggestions for getting through traumatic life events like breakups and pregnancy loss. So when one of our listeners suggested we make a...

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Ben Sinclair Is A Fan Of Endings

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For fans of the HBO series High Maintenance, Ben Sinclair is practically synonymous with “The Guy,” the laid-back New York City weed dealer he plays on the show. And while a lot of the show is inspire...

18 Mar 202026min

Alone Together: A COVID-19 Call-In

Alone Together: A COVID-19 Call-In

Over the last few weeks and days, the COVID-19 pandemic has drastically reshaped many of our lives. For some of us, we're working from home, our kids aren't in school, and we're worried about our own ...

13 Mar 20200s

Why You're Not Having Sex

Why You're Not Having Sex

A 34-year-old listener we’ll call “Marie” emailed us back in 2015. She’d never dated anyone seriously. She'd never been kissed, and she'd never had sex. She wasn't opposed to any of those things. They...

11 Mar 202035min

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