Unlocking Antibody Development with AI with Dr. Pin-Kuang Lai
BioTalk Unzipped12 Sep 2025

Unlocking Antibody Development with AI with Dr. Pin-Kuang Lai

In this episode of BioTalk Unzipped, hosts Gregory Austin and Dr. Chad Briscoe interview Asst. Professor Pin-Kuang Lai from Stevens Institute of Technology about his keynote speech at AAPS NBC 2025 and the intersection of AI and molecular engineering, particularly in predicting the viscosity of monoclonal antibodies. They discuss the challenges of high concentration formulations, the importance of AI validation, and the future of formulation development. Lai shares insights from his international research journey and collaborations with pharmaceutical companies, as well as opportunities for students interested in this field.

00:00 Preview & Intro

01:58 Deep Viscosity and AI in Antibody Development

04:39 AI Validation and Model Reliability

07:12 International Journey and Collaborative Research

08:42 Future of Formulation Development

10:30 AAPS NBC Experience

11:30 Academic vs. Industry Career Paths

12:31 Collaboration with Pharmaceutical Companies

13:59 Modeling Protein Aggregation Challenges

14:43 Student Engagement and Research Opportunities

15:45 Expanding Applications of Machine Learning

Dr. Pin-Kuang Lai

https://www.linkedin.com/in/pin-kuang-lai/

Stevens Institute of Technology - https://www.stevens.edu/

Dr. Lai’s Publications - https://www.linkedin.com/in/pin-kuang-lai/details/publications/

The DeepViscosity Model - https://devpred.onrender.com/DeepViscosity

Dr. Chad Briscoe

https://www.linkedin.com/in/chadbriscoe/

Celerion - https://www.celerion.com/


Gregory Austin

https://www.linkedin.com/in/gregoryaustin1/

Celerion - https://www.celerion.com/

Episoder(41)

How AI is Helping Diagnose Disease with Chuck Piccirillo

How AI is Helping Diagnose Disease with Chuck Piccirillo

Summary In this conversation, Gregory Austin and Chad Briscoe interview Chuck Piccirillo, CEO of Zealic Health, about his experience in the healthcare industry and the focus on patient-centric soluti...

2 Aug 202438min

Reptiles, Treatments, and Cell-Gene Therapy with Dr. Vick

Reptiles, Treatments, and Cell-Gene Therapy with Dr. Vick

Summary Dr. Andy Vick shares some of the things that surprised him throughout his career and he discusses his passion for reptiles and his experience discussing the pharmaceutical potential of venom w...

15 Jul 202438min

Amyloidosis Exposed: New Hope with Dr. Vick

Amyloidosis Exposed: New Hope with Dr. Vick

Summary Dr. Andy Vick discusses his work at Attralus Therapeutics, a biotech company focused on developing treatments for systemic amyloidosis. He explains the etiology of the disease and how Attralus...

1 Jul 202440min

A Diagnostic Breakthrough for Alzheimer’s with Dr. Jonathon Hill

A Diagnostic Breakthrough for Alzheimer’s with Dr. Jonathon Hill

A Diagnostic Breakthrough for Alzheimer’s Summary In this conversation, Dr. Jonathan Hill discusses his work in nanopore sequencing-based technology and its applications in genetic and epigenetic rese...

1 Jun 202430min

The AI Prescription: Revolutionizing Pharma & Patient Care with Jason Burke

The AI Prescription: Revolutionizing Pharma & Patient Care with Jason Burke

The AI Prescription: Revolutionizing Pharma & Patient Care with Jason Burke Summary In Episode 13, Jason Burke discusses the unique approach of the Duke program in providing real-world healthcare data...

15 Mai 202435min

Unlocking the Future of Healthcare with Organoids, AI, and Quantum Computing with Jason Burke

Unlocking the Future of Healthcare with Organoids, AI, and Quantum Computing with Jason Burke

Summary In this episode of BioTalk Unzipped, the hosts discuss the applications and ethical concerns surrounding organoids, which are 3D cell clusters that mimic the features of full-sized organs. The...

1 Mai 202434min

Breakthrough in Melanoma, Rare Diseases, and Curative Therapies with Scott Schliebner

Breakthrough in Melanoma, Rare Diseases, and Curative Therapies with Scott Schliebner

Summary In this episode, Scott Schliebner discusses the unique challenges and complexities of rare disease trials. He highlights the difficulties in recruiting patients, the multidisciplinary nature o...

15 Apr 202436min

Impact of AI in Rare Disease Trials with Scott Schliebner

Impact of AI in Rare Disease Trials with Scott Schliebner

Impact of AI in Rare Disease Trials with Scott Schliebner Summary In this episode, the hosts welcome Scott Schliebner as their guest and kick off with a charitable act, donating to Rare Givers. They d...

1 Apr 202436min

Populært innen Business og økonomi

lydartikler-fra-aftenposten
stopp-verden
dine-penger-pengeradet
e24-podden
rss-penger-polser-og-politikk
rss-borsmorgen-okonominyhetene
pengepodden-2
finansredaksjonen
utbytte
livet-pa-veien-med-jan-erik-larssen
pengesnakk
stormkast-med-valebrokk-stordalen
okonomiamatorene
morgenkaffen-med-finansavisen
liberal-halvtime
tid-er-penger-en-podcast-med-peter-warren
rss-politisk-preik
lederpodden
rss-pa-konto
rss-fa-makro