#337: This Tiny Molecule Can Tackle Inflammation & Immune Health - Diving into KPV with Nathalie Niddam
In this special solo episode, it's just me, Nathalie Niddam—nutritionist, human potential and epigenetic coach—returning to my roots and diving deep into the world of peptides. Today, I'm shining a spotlight on KPV, a fascinating and often overlooked peptide with powerful anti-inflammatory, antimicrobial, and healing properties. What We Discuss: What are peptides? Clearing up misconceptions ... 00:01:00 KPV explained: structure and origins ... 00:03:00 How KPV works (anti-inflammatory mechanisms) ... 00:05:00 Comparison to Melanotan and tanning ... 00:08:00 KPV benefits: gut, antimicrobial, healing, immune modulation ... 00:09:00 KPV for gut and skin health ... 00:14:00 Neuroprotection and research potential ... 00:18:00 Administration methods: oral, topical, injectable ... 00:19:00 Safety profile and side effects ... 00:22:00 Tracking protocols and the Peptide Pro app ... 00:24:00 Recap and concluding remarks ... 00:30:00 Our Amazing Sponsor: BiOptimizers - MassZymes is the most complete, most potent digestive enzyme with over 102% MORE PROTEASE than the nearest competitor. That's crucial because protein is the most complex macronutrient to break down. Try MassZymes at bioptimizers.com/bionat and enter the coupon code BIONAT to get 10% off your order. More From Nat: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group
23 Mai 32min
#336: Hormone Replenishment, Digestive Rest, & Creatine: A Fresh Approach to Women's Longevity With Cynthia Thurlow
Today, I'm joined by Cynthia Thurlow, a remarkable nurse practitioner, podcast host, and true hormone whisperer who is on a mission to help women thrive through perimenopause and beyond. What We Discuss: Perimenopause, menopause, and longevity connection ... 00:06:09 Hormone misunderstandings and HRT discussion ... 00:07:34 Cynthia's clinical experience and women's health ... 00:07:53 Recognizing hormonal imbalances and PCOS in young women ... 00:12:09 Autoimmunity risks and thyroid issues ... 00:19:55 Lifestyle factors: aging, processed food, and alcohol ... 00:24:02 Fasting, digestive rest, and metabolic flexibility ... 00:35:02 Practical fasting tips for different age groups ... 00:36:38 Diet flexibility and protein-forward meals ... 00:41:26 Meal timing, circadian rhythm, and satiety ... 00:56:04 Muscle loss, strength training, and optimal protein ... 01:00:36 Gut microbiome recovery and dietary diversity ... 01:06:15 Creatine: benefits, dosing, and sourcing ... 01:08:36 Where to find Cynthia and her products ... 01:15:30 Thank You To Our Sponsors: Peptide Pro App: can help manage every part of your peptide protocol. From smart scheduling to real-time dose checklists, note taking, and easy calculations. Listeners receive 50% off for the first month. Visit www.peptidepro.app to download the app and use code NATHALIE50 to get started today. BEAM - These minerals come from humate, a natural substance formed over millions of years as freshwater plants broke down and deposited their nutrients into the soil. Over time, those minerals concentrated into this black, crystalline material that's now one of the most mineral-dense substances on earth. That's what's going into your body—and your cells absorb it within minutes. Visit https://www.beamminerals.com/NAT20 and use code NAT20 for 20% off. Wizard Sciences - Mitoblue - Everything in the formula is there to help you think clearer, move better, and stay resilient—mentally and physically - Methylene Blue, NMN, PQQ, Apigenin and Ginseng. Go to wizardsciences.com and look for MitoBlue. Use code NAT15 at checkout to get 15% off your purchase. Learn more from Cynthia Thurlow: Website Twitter Instagram Facebook LinkedIn Youtube Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group
20 Mai 1h 17min
#335 Unlocking VO2 Max: TIME-Saving Secrets (Why Zone 2 Alone Won't Cut It) | REHIT and Metabolic Health With Ulrich Dempfle
Today, I'm joined by Ulrich Dempfle, the innovative mind behind the CAROL Bike. Ulrich's journey is fascinating—he started as a mechanical engineer in Europe, became a pioneer in hospital AI systems, and is now laser-focused on bringing cutting-edge fitness tech to regular people, like you and me. What we discuss: Zone 2 training: hype, benefits, and limitations ... 00:08:00 VO2 max: definition and importance for longevity ... 00:10:00 The impracticality and issues with Zone 2 for most people ... 00:15:00 Downsides of long-duration steady-state cardio ... 00:18:00 Why strength and mobility also matter ... 00:17:00 Carol Bike and REHIT: efficient fitness for longevity ... 00:31:00 REHIT's proven VO2 max and metabolic improvements ... 00:36:00 Personalization and ease-of-use with Carol Bike ... 00:49:00 Carol Bike's versatility: multiple workouts and app integrations ... 00:57:00 Who Carol Bike is for and safety notes ... 01:10:00 Carol Bike trial info, research, and closing ... 01:12:00 Our Amazing Sponsors: Troscriptions - Blue Cannatine - think of it as a small but mighty brain boost that melts in your mouth. A precise blend of methylene blue, caffeine, CBD, and microdosed nicotine gives me steady energy, focus, and mental clarity without the usual ups and downs. Try it for yourself at troscriptions.com and use code NAT10 for 10% off. Get in the zone and stay there. Timeline: Mitopure®️ is a breakthrough supplement that promotes cellular renewal. It contains Urolithin A, which helps your body clear out damaged mitochondria and create new, efficient ones—giving you more sustainable energy. Timeline is offering 10% off your order of Mitopure now. Go to timeline.com/NAT10. Profound Health - Nature's Marvels have been making bioregulators for over a decade, working directly with Prof. Khavinson, the pioneer of Bioregulator science! They're manufactured in the UK. They're GMP and HACCP certified and FDA-compliant. Whatever your health needs, there's a bioregulator for you. Head to profound-health.com and use code NAT15 for 15% off your first order. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group
16 Mai 1h 16min
#334: Iron Overload | More Common Than You Think - Fatigue, Low Testosterone, Joint Pain, Hair Loss, Gut Issues & More - What To Do About It With Christy Sutton
Today, I sit down with Dr. Christy Sutton, author of The Iron Curse and an expert whose personal journey through her husband's long and confusing health saga opened her eyes to the often-missed danger of hereditary hemochromatosis. What we discuss: Meet Dr. Christy Sutton and Her Personal Story ... 00:06:00 Hemochromatosis: Genetics, Diagnosis, and Mistreatment ... 00:11:00 Multi-Organ Impact of Iron Overload ... 00:33:00 Childhood Hemochromatosis and Clinical Blind Spots ... 00:37:00 A five-year-old's story reveals difficulties in pediatric diagnosis and innovative, non-blood-removal strategies. Symptoms, Infections, and Iron ... 00:47:00 Systemic issues like joint pain, anxiety, dementia, and heightened risk of deadly infections. Managing and Lowering Iron Levels ... 01:01:00 Genetic Roots: Red Hair, Irish Heritage, and Family Risk ... 01:09:00 Key Takeaways and Resources ... 01:17:00 Screening recommendations, where to find Dr. Sutton's work, and closing comments for listeners. Our Amazing Sponsors: Puori: If you want clean, high-quality protein without the mystery contaminants, check out Puori PW1. Receive 20% off a one-time purchase or if you choose the already discounted subscription, you get almost a third off the price! Visit Puori.com/NAT and use my promo code NAT. Young Goose L.A.D.R. Serum - Powered by light-activated DNA repair enzymes, NAD+, and collagen peptides, it reverses damage while you go about your life. Sunlight? Red light therapy? It all helps this serum work smarter, not harder. Visit YoungGoose.com—use code NAT10 to get started, or 5NAT if you're an existing customer. Future-proof your face. Fresh-Pressed Olive Oil Club: As an introduction to his Fresh-Pressed Olive Oil Club, T. J. is willing to send you a full-size $39 bottle of one of the world's finest artisanal olive oils — fresh from the new harvest—for just $1 to help him cover shipping. No commitment to buy anything, now or ever. Go to GetFreshLongevity.com for a free bottle and pay just $1. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group
13 Mai 1h 20min
#333: Keto Myths, Carb Days, and Why Calories Don't Count | Ben Azadi on Breaking the Weight Loss Cycle
Today I'm excited to bring you a conversation with my friend and special guest, Ben Azadi—founder of Keto Kamp and author of Metabolic Freedom. In this episode, Ben and I take on some of the most stubborn myths around metabolism and weight loss, especially the widely held belief that "calories in, calories out" is the key to health. What we discuss: Why calorie-counting fails and metabolic flexibility matters ... 00:03:39 Biggest Loser study and gut health ... 00:11:14 Processed foods, seed oils, and saturated fats explained ... 00:17:07 Keto diet evolution, mistakes, and carb cycling ... 00:26:48 Dr. Pompa's metabolic variation protocols ... 00:37:41 Intermittent fasting pitfalls and how to fast smart ... 00:41:54 Meal frequency and metabolism myths ... 00:45:59 Muscle mass as metabolic health foundation ... 00:47:00 Who benefits—and who doesn't—from keto ... 00:50:12 Hidden blood sugar spikes from "health foods" ... 00:53:23 Ben's top tip: Vitamin G (gratitude) ... 00:55:15 Why weight regain happens after keto—self-image ... 00:58:27 Gender differences in keto response ... 01:01:50 Where to find Ben Azadi and Metabolic Freedom ... 01:03:37 Our Amazing Sponsors: Quantum Upgrade - Imagine plugging yourself into a limitless power source. It's been rigorously tested and shown to improve blood flow, reduce stress, and even boost cellular energy by up to 29%.Try it today at quantumupgrade.io/NAT and start running life, instead of life running you. Use my code NAT15 to get a 15-day free trial on the All-in-One Frequency Bundle. Good through June 1st, 2025 Peptide Pro App: can help manage every part of your peptide protocol. From smart scheduling to real-time dose checklists, note taking, and easy calculations. Listeners receive 50% off for the first month. Visit www.peptidepro.app to download the app and use code NATHALIE50 to get started today. BiOptimizers - MassZymes is the most complete, most potent digestive enzyme with over 102% MORE PROTEASE than the nearest competitor. That's crucial, because protein is the most complex macronutrient to break down. Try MassZymes at bioptimizers.com/bionat and enter the coupon code BIONAT to get 10% off your order. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group
9 Mai 1h 5min
#332: Ben Greenfield Reveals Latest Biohacks, Peptide Routines, and Detox Tips for Longevity
If you've been anywhere near health optimization circles, you already know Ben Greenfield as a NYT bestselling author, former Ironman triathlete, coach, one of the OGs of biohacking. Today, he's my guest on the Longevity podcast. What we discuss: Ben's new home, cold exposure, and microdosing cryotherapy ... 00:06 Writing, updating, and revising "Boundless" ... 00:09 Key updates: Self-quantification, longevity, new detox protocols ... 00:12 High-tech blood filtration and its impact ... 00:15 Daily detox strategies: Lymphatic movement, sauna, exercise ... 00:17 Ben's evolution: From strict keto to Mediterranean-style eating ... 00:21 Genetics, ancestry, and personalized nutrition lessons ... 00:23 Impact of endurance training, hormone and gut issues, recovery via flexible dieting ... 00:27 Addressing high coronary plaque: Statins, PCSK9 inhibitors, supplementation ... 00:35 Tracking heart health non-invasively (CIMT) ... 00:38 Thoughtful, limited use of pharmaceuticals for health ... 00:44 Peptides: Orals, protocols, favorites (BPC-157, TA1, etc.) ... 00:47 GLP-1 agonists: Powerful but require careful dosing ... 00:51 Biohacks gone wrong: Dosing mishaps and psychedelic stories ... 00:55 Ben's three core tips: Family time, naps, and prayer ... 00:58 Our Amazing Sponsors: Wizard Sciences - Mitoblue Everything in the formula is there to help you think clearer, move better, and stay resilient mentally and physically - Methylene Blue, NMN, PQQ, Apigenin and Ginseng. Go to wizardsciences.com and look for MitoBlue. Use code NAT15 at checkout to get 15% off your purchase. Mitolux NEW Second Generation - This second-generation red and near-infrared light therapy panel hits all the marks. Two new wavelengths—810nm and 940nm—target brain performance, deep muscle recovery, and circulation. I use GAMA mode when I want to lock in focus, and Fireplace 2 when I want to wind down. Get a Mitolux BTS2 Sunlamp for 10% off at https://mitolux.com/NAT10, NAT10 will be automatically applied at checkout. LVLUP - Neuro Re-Generate the world's first liposomal triple peptide formula, designed to support mental clarity, focus, and overall brain health. Visit www.lvluphealth.com and use code NAT for 20% off your order. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group
6 Mai 1h 1min
#331: Can Exosomes Wake Up the Body's Dormant Healing Powers? Dr. Ed Park Shares Insights On How Exosomes Can Help Heal Intense Pain, Acute Injury, and More.
In this episode, I dive deep into the transformative world of regenerative medicine with Dr. Ed Park—a leader who has spent nearly two decades pushing the boundaries of aging and healing. Curious about exosomes and how these tiny biological messengers are redefining our ability to recover from injury, illness, and even chronic conditions? You'll love this conversation. What we discuss: Why exosomes? Origins, discovery, and benefits of stem cells ... 00:03:00 How exosomes communicate and trigger healing ... 00:06:00 Exosomes for neurological repair and brain injuries ... 00:10:00 Exosome delivery: IV, targeting, and blood-brain barrier ... 00:12:00 Exosomes in musculoskeletal injuries and healing rates ... 00:18:00 Patient selection, expectations, and placebo effects ... 00:23:00 Exosomes for immune system support and aging ... 00:30:00 Lifestyle pillars alongside regenerative medicine ... 00:32:00 Exosomes in cardiac and nerve repair ... 00:34:00 Provider training, resources, and Dr. Park's practice ... 00:43:00 Closing remarks and medical disclaimer ... 00:45:00 Our Amazing Sponsors: Timeline: Mitopure: is a breakthrough supplement that promotes cellular renewal. It contains Urolithin A, which helps your body clear out damaged mitochondria and create new, efficient ones—giving you more sustainable energy. Timeline is offering 10% off your order of Mitopure now. Go to timeline.com/NAT10. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group
2 Mai 45min
#330: Lose the Bloat, Fix Your GUT: Inside the Microbiome Revolution (Skin, Weight & Longevity Secrets) with Dr William Davis
On this episode of the Longevity Podcast, host Nathalie Niddam is joined by renowned cardiologist and bestselling author Dr. William Davis for a deep dive into the powerful connection between gut health, the microbiome, and vibrant longevity. Dr. Davis—who made waves with his groundbreaking books Wheat Belly and Super Gut—shares his journey from mainstream cardiology to pioneering work on the true drivers behind chronic disease, fat gain, and aging. What we discuss: Meet Dr. William Davis & Wheat Belly origins ... 00:04:00 From cholesterol to calcium scoring ... 00:10:00 Dramatic health wins from removing wheat, grains, sugar ... 00:14:00 Transition to the microbiome & SIBO ... 00:19:00 Modern SIBO causes and prevalence ... 00:24:00 SIBO yogurt strategy and benefits ... 00:31:00 Women's health, pregnancy, and key microbes ... 00:47:00 Actionable gut health tips and food swaps ... 01:03:00 Fermentation: dos and don'ts ... 01:21:00 Where to find Dr. Davis and wrap-up ... 01:23:00 Our Amazing Sponsors: Peptide Pro App: can help manage every part of your peptide protocol. From smart scheduling to real-time dose checklists, note taking, and easy calculations. Listeners receive 50% off for the first month. Visit www.peptidepro.app to download the app and use code NATHALIE50 to get started today. Puori - 21 grams of high-quality whey protein from pasture-raised cows with no hormones, GMOs, or pesticides. Ready to ditch the questionable protein powders? Visit Puori.com/NAT and use my code NAT to get 20% off your first order! Profound Health - Nature's Marvels have been making bioregulators for over a decade, working directly with Prof. Khavinson, the pioneer of Bioregulator science! They're manufactured in the UK. They're GMP and HACCP certified and FDA-compliant. Head to profound-health.com and use code NAT15 for 15% off your first order. Nat's Links: YouTube Channel Join My Membership Community Sign up for My Newsletter Instagram Facebook Group
29 Apr 1h 27min
